Molecular and Cellular Pharmacology

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2009

Protein tyrosine phosphatase receptor type O regulates development and function of the sensory nervous system

Gonzalez-Brito, M. R. & Bixby, J. L., Nov 1 2009, In : Molecular and Cellular Neuroscience. 42, 4, p. 458-465 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Quantitative assessment of islet cell products: Estimating the accuracy of the existing protocol and accounting for islet size distribution

Buchwald, P., Wang, X., Khan, A., Bernal, A., Fraker, C., Inverardi, L. & Ricordi, C., Dec 1 2009, In : Cell Transplantation. 18, 10-11, p. 1223-1235 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics

Greenberg, M. J., Watt, J. D., Jones, M., Kazmierczak, K., Szczesna-Cordary, D. & Moore, J. R., Jan 1 2009, In : Journal of Molecular and Cellular Cardiology. 46, 1, p. 108-115 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Removal of the cardiac myosin regulatory light chain increases isometric force production

Pant, K., Watt, J., Greenberg, M., Jones, M., Szczesna-Cordary, D. & Moore, J. R., Oct 1 2009, In : FASEB Journal. 23, 10, p. 3571-3580 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Sex-specific impact of aldosterone receptor antagonism on ventricular remodeling and gene expression after myocardial infarction

Kanashiro-Takeuchi, R. M., Heidecker, B., Lamirault, G., Dharamsi, J. W. & Hare, J. M., Jan 1 2009, In : Clinical and Translational Science. 2, 2, p. 134-142 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Small-molecule costimulatory blockade: Organic dye inhibitors of the CD40-CD154 interaction

Margolles-Clark, E., Umland, O., Kenyon, N. S., Ricordi, C. & Buchwald, P., Nov 1 2009, In : Journal of Molecular Medicine. 87, 11, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Suramin inhibits the CD40-CD154 costimulatory interaction: A possible mechanism for immunosuppressive effects

Margolles-Clark, E., Jacques-Silva, M. C., Ganesan, L., Umland, O., Kenyon, N. S., Ricordi, C., Berggren, P-O. Y. & Buchwald, P., Apr 1 2009, In : Biochemical Pharmacology. 77, 7, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Teach, then trust Elizabeth W. Jones (1939-2008): mentor to many.

Connelly, T. D., Lemmon, S. K., Mitchell, A. P. & Woolford, J., Feb 2009, In : Genetics. 181, 2, p. 357-365 9 p.

Research output: Contribution to journalArticle

The Conserved NDR Kinase Orb6 Controls Polarized Cell Growth by Spatial Regulation of the Small GTPase Cdc42

Das, M., Wiley, D. J., Chen, X., Shah, K. & Verde, F., Aug 11 2009, In : Current Biology. 19, 15, p. 1314-1319 6 p.

Research output: Contribution to journalArticle

55 Scopus citations

The F-BAR Protein Syp1 Negatively Regulates WASp-Arp2/3 Complex Activity during Endocytic Patch Formation

Boettner, D. R., D'Agostino, J. L., Torres, O. T., Daugherty-Clarke, K., Uygur, A., Reider, A., Wendland, B., Lemmon, S. K. & Goode, B. L., Dec 15 2009, In : Current Biology. 19, 23, p. 1979-1987 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
35 Scopus citations

The molecular effects of skeletal muscle myosin regulatory light chain phosphorylation

Greenberg, M. J., Mealy, T. R., Watt, J. D., Jones, M., Szczesna-Cordary, D. & Moore, J. R., Aug 2009, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 297, 2, p. R265-R274

Research output: Contribution to journalArticle

48 Scopus citations

The Role of the N-Terminus of the Myosin Essential Light Chain in Cardiac Muscle Contraction

Kazmierczak, K., Xu, Y., Jones, M., Guzman, G., Hernandez, O. M., Kerrick, W. G. L. & Szczesna-Cordary, D., Apr 3 2009, In : Journal of molecular biology. 387, 3, p. 706-725 20 p.

Research output: Contribution to journalArticle

40 Scopus citations
2008

Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation

Yin, L., Locovei, A. M. & D'Urso, G., Oct 2008, In : Molecular biology of the cell. 19, 10, p. 4374-4382 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

A Myc-slug (Snail 2)/Twist regulatory circuit directs vascular development

Rodrigues, C. O., Nerlick, S. T., White, E. L., Cleveland, J. L. & King, M. L., Jun 2008, In : Development. 135, 11, p. 1903-1911 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

A new in vitro model of the glial scar inhibits axon growth

Wanner, I. B., Deik, A., Torres, M., Rosendahl, A., Neary, J. T., Lemmon, V. P. & Bixby, J. L., Dec 1 2008, In : Glia. 56, 15, p. 1691-1709 19 p.

Research output: Contribution to journalArticle

103 Scopus citations

A novel angiographic methodology for the quantification of angiogenesis

Gounis, M. J., Lieber, B. B., Webster, K. A. & Wakhloo, A. K., Mar 1 2008, In : IEEE Transactions on Biomedical Engineering. 55, 3, p. 996-1003 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin

Pinto, J. R., Parvatiyar, M. S., Jones, M. A., Liang, J. & Potter, J. D., Jan 25 2008, In : Journal of Biological Chemistry. 283, 4, p. 2156-2166 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Bot1p is required for mitochondrial translation, respiratory function, and normal cell morphology in the fission yeast Schizosaccharomyces pombe

Wiley, D. J., Catanuto, P., Fontanesi, F., Rios, C., Sanchez, N., Barrientos, A. & Verde, F., Apr 1 2008, In : Eukaryotic Cell. 7, 4, p. 619-629 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Brief report: A GPR54-activating mutation in a patient with central precocious puberty

Teles, M. G., Bianco, S. D. C., Brito, V. N., Trarbach, E. B., Kuohung, W., Xu, S., Seminara, S. B., Mendonca, B. B., Kaiser, U. B. & Latronico, A. C., Feb 14 2008, In : New England Journal of Medicine. 358, 7, p. 709-715 7 p.

Research output: Contribution to journalArticle

347 Scopus citations

Cardiac troponin T forms a tetramer in vitro

Lounes, K. C., Demeler, B., Anderson, D. E., Gomes, A. W., Potter, J. D., Nassar, R. & Anderson, P. A. W., Feb 19 2008, In : Biochemistry. 47, 7, p. 1970-1976 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
34 Scopus citations

Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II)

Schröter, T., Minond, D., Weiser, A., Dao, C., Habel, J., Spicer, T., Chase, P., Baillargeon, P., Scampavia, L., Schürer, S., Chung, C., Mader, C., Southern, M., Tsinoremas, N., LoGrasso, P. & Hodder, P., Feb 2008, In : Journal of Biomolecular Screening. 13, 1, p. 17-28 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

EST express: PHP/MySQL based automated annotation of ESTs from expression libraries

Smith, R. P., Buchser, W. J., Lemmon, M. B., Pardinas, J. R., Bixby, J. L. & Lemmon, V. P., Apr 10 2008, In : BMC Bioinformatics. 9, 186.

Research output: Contribution to journalArticle

3 Scopus citations

Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice

Wen, Y., Pinto, J. R., Gomes, A. V., Xu, Y., Wang, Y., Wang, Y., Potter, J. D. & Kerrick, W. G. L., Jul 18 2008, In : Journal of Biological Chemistry. 283, 29, p. 20484-20494 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Functional deficits in nNOSμ-deficient skeletal muscle: Myopathy in nNOS knockout mice

Percival, J. M., Anderson, K. N. E., Gregorevic, P., Chamberlain, J. S. & Froehner, S. C., Oct 13 2008, In : PloS one. 3, 10, e3387.

Research output: Contribution to journalArticle

66 Scopus citations

Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

Buchwald, P., Feb 1 2008, In : Steroids. 73, 2, p. 193-208 16 p.

Research output: Contribution to journalArticle

31 Scopus citations

High-throughput screening for human galactokinase inhibitors

Wierenga, K. J., Lai, K., Buchwald, P. & Tang, M., Aug 1 2008, In : Journal of Biomolecular Screening. 13, 5, p. 415-423 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

High tolerance for ionizable residues in the hydrophobic interior of proteins

Isom, D. G., Cannon, B. R., Castañeda, C. A., Robinson, A. & García-Moreno E., B., Nov 18 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 46, p. 17784-17788 5 p.

Research output: Contribution to journalArticle

106 Scopus citations

Ligand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancer

Lyons, L. S., Rao, S., Balkan, W., Faysal, J., Maiorino, C. A. & Burnstein, K. L., Mar 1 2008, In : Molecular Endocrinology. 22, 3, p. 597-608 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C

Landstrom, A. P., Parvatiyar, M. S., Pinto, J. R., Marquardt, M. L., Bos, J. M., Tester, D. J., Ommen, S. R., Potter, J. D. & Ackerman, M. J., Aug 1 2008, In : Journal of Molecular and Cellular Cardiology. 45, 2, p. 281-288 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

MsrA protects cardiac myocytes against hypoxia/reoxygenation induced cell death

Prentice, H. M., Moench, I. A., Rickaway, Z. T., Dougherty, C. J., Webster, K. A. & Weissbach, H., Feb 15 2008, In : Biochemical and biophysical research communications. 366, 3, p. 775-778 4 p.

Research output: Contribution to journalArticle

45 Scopus citations

Myofilament Ca2+ sensitization causes susceptibility to cardiac arrhythmia in mice

Baudenbacher, F., Schober, T., Pinto, J. R., Sidorov, V. Y., Hilliard, F., Solaro, R. J., Potter, J. D. & Knollmann, B. C., Dec 1 2008, In : Journal of Clinical Investigation. 118, 12, p. 3893-3903 11 p.

Research output: Contribution to journalArticle

158 Scopus citations

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration

Zhai, R. G., Zhang, F., Hiesinger, P. R., Cao, Y., Haueter, C. M. & Bellen, H. J., Apr 17 2008, In : Nature. 452, 7189, p. 887-891 5 p.

Research output: Contribution to journalArticle

143 Scopus citations

Pharmacokinetics of the sequential metabolites of loteprednol etabonate in rats

Wu, W. M., Huang, F., Lee, Y., Buchwald, P. & Bodor, N., Mar 1 2008, In : Journal of Pharmacy and Pharmacology. 60, 3, p. 291-297 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gβ5 complexes in brain

Grabowska, D., Jayaraman, M., Kaltenbronn, K. M., Sandiford, S. L., Wang, Q., Jenkins, S., Slepak, V. Z., Smith, Y. & Blumer, K. J., Feb 19 2008, In : Neuroscience. 151, 4, p. 969-982 14 p.

Research output: Contribution to journalArticle

32 Scopus citations

Proteomics in Trypanosoma cruzi- Localization of novel proteins to various organelles

Ferella, M., Nilsson, D., Darban, H., Rodrigues, C., Bontempi, E. J., Docampo, R. & Andersson, B., Jul 1 2008, In : Proteomics. 8, 13, p. 2735-2749 15 p.

Research output: Contribution to journalArticle

52 Scopus citations

Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300

Wei, J. Q., Shehadeh, L. A., Mitrani, J. M., Pessanha, M., Slepak, T. I., Webster, K. A. & Bishopric, N. H., Aug 26 2008, In : Circulation. 118, 9, p. 934-946 13 p.

Research output: Contribution to journalArticle

79 Scopus citations

Retrometabolic drug design: Principles and recent developments

Bodor, N. & Buchwald, P., Aug 1 2008, In : Pure and Applied Chemistry. 80, 8, p. 1669-1682 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Robust hypoxia-selective regulation of a retinal pigment epithelium-specific adeno-associated virus vector

Dougherty, C. J., Smith, G. W., Dorey, C. K., Prentice, H. M., Webster, K. A. & Blanks, J. C., Mar 7 2008, In : Molecular vision. 14, p. 471-480 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Schizosaccharomyces pombe Orc5 plays multiple roles in the maintenance of genome stability throughout the cell cycle

Kato, H., Matsunaga, F., Miyazaki, S., Yin, L., D'Urso, G., Tanaka, K. & Murakami, Y., Apr 15 2008, In : Cell Cycle. 7, 8, p. 1083-1094 12 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Soft corticosteroids for local immunosuppression: Exploring the possibility for the use of loteprednol etabonate for islet transplantation

Bocca, N., Pileggi, A., Molano, R. D., Marzorati, S., Wu, W., Bodor, N., Ricordi, C. & Buchwald, P., Mar 1 2008, In : Pharmazie. 63, 3, p. 226-232 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Stereoisomers of N-substituted soft anticholinergics and their zwitterionic metabolite based on glycopyrrolate - Syntheses and pharmacological evaluations

Wu, W. M., Wu, J., Mori, N., Buchwald, P. & Bodor, N., Mar 1 2008, In : Pharmazie. 63, 3, p. 200-209 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Troponin and cardiomyopathy

Chang, A. N., Parvatiyar, M. S. & Potter, J. D., Apr 25 2008, In : Biochemical and biophysical research communications. 369, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Zinc potentiates neuronal nicotinic receptors by increasing burst duration

Hsiao, B., Mihalak, K. B., Magleby, K. L. & Luetje, C. W., Feb 1 2008, In : Journal of neurophysiology. 99, 2, p. 999-1007 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2007

A general bilinear model to describe growth or decline time profiles

Buchwald, P., Jan 1 2007, In : Mathematical Biosciences. 205, 1, p. 108-136 29 p.

Research output: Contribution to journalArticle

27 Scopus citations

A honey bee odorant receptor for the queen substance 9-oxo-2-decenoic acid

Wanner, K. W., Nichols, A. S., Walden, K. K. O., Brockmann, A., Luetje, C. W. & Robertson, H. M., Sep 4 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 36, p. 14383-14388 6 p.

Research output: Contribution to journalArticle

131 Scopus citations

Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their Activity

Hanson, S. M., Cleghorn, W. M., Francis, D. J., Vishnivetskiy, S. A., Raman, D., Song, X., Nair, K. S., Slepak, V. Z., Klug, C. S. & Gurevich, V. V., Apr 27 2007, In : Journal of molecular biology. 368, 2, p. 375-387 13 p.

Research output: Contribution to journalArticle

88 Scopus citations

Coping with cyclic oxygen availability: Evolutionary aspects

Flück, M., Webster, K. A., Graham, J., Giomi, F., Gerlach, F. & Schmitz, A., Oct 1 2007, In : Integrative and comparative biology. 47, 4, p. 524-531 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Fast skeletal muscle regulatory light chain is required for fast and slow skeletal muscle development

Wang, Y., Szczesna-Cordary, D., Craig, R., Diaz-Perez, Z., Guzman, G., Miller, T. & Potter, J. D., Jul 2007, In : FASEB Journal. 21, 9, p. 2205-2214 10 p.

Research output: Contribution to journalArticle

17 Scopus citations