Molecular and Cellular Pharmacology

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Functional assay of mammalian and insect olfactory receptors using Xenopus oocytes.

Luetje, C. W., Nichols, A. S., Castro, A. & Sherman, B. L., Oct 4 2013, In : Methods in molecular biology (Clifton, N.J.). 1003, p. 187-202 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

Functional characterization of the two isoforms of troponin C from the arthropod Balanus nubilus

Ashley, C. C., Lea, T. J., Hoar, P. E., Kerrick, W. G. L., Strang, P. F. & Potter, J. D., Dec 1 1991, In : Journal of Muscle Research and Cell Motility. 12, 6, p. 532-542 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Functional characterization of TNNC1 rare variants identified in dilated cardiomyopathy

Pinto, J. R., Siegfried, J. D., Parvatiyar, M. S., Li, D., Norton, N., Jones, M. A., Liang, J., Potter, J. D. & Hershberger, R. E., Oct 30 2011, In : Journal of Biological Chemistry. 286, 39, p. 34404-34412 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Functional characterizations of rare UBA1 variants in X-linked Spinal Muscular Atrophy

Baumbach-Reardon, L., Balak, C. D., Hunter, J. M., Ahearn, M. E., Wiley, D. & D'urso, G., 2017, In : F1000Research. 6, 1636.

Research output: Contribution to journalArticle

5 Scopus citations

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in α-tropomyosin

Chang, A. N., Harada, K., Ackerman, M. J. & Potter, J. D., Oct 7 2005, In : Journal of Biological Chemistry. 280, 40, p. 34343-34349 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice

Wen, Y., Pinto, J. R., Gomes, A. V., Xu, Y., Wang, Y., Wang, Y., Potter, J. D. & Kerrick, W. G. L., Jul 18 2008, In : Journal of Biological Chemistry. 283, 29, p. 20484-20494 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Functional deficits in nNOSμ-deficient skeletal muscle: Myopathy in nNOS knockout mice

Percival, J. M., Anderson, K. N. E., Gregorevic, P., Chamberlain, J. S. & Froehner, S. C., Oct 13 2008, In : PloS one. 3, 10, e3387.

Research output: Contribution to journalArticle

67 Scopus citations

Functional diversity of neuronal nicotinic acetylcholine receptors

Patrick, J., Séquéla, P., Vernino, S., Amador, M., Luetje, C. & Dani, J. A., Jan 1 1993, In : Progress in brain research. 98, C, p. 113-120 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Functional Effects of a Restrictive-Cardiomyopathy-Linked Cardiac Troponin I Mutation (R145W) in Transgenic Mice

Wen, Y., Xu, Y., Wang, Y., Pinto, J. R., Potter, J. D. & Kerrick, W. G. L., Oct 9 2009, In : Journal of molecular biology. 392, 5, p. 1158-1167 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Fusigenic liposome-mediated DNA transfer into cardiac myocytes

Ellison, K. E., Bishopric, N. H., Webster, K. A., Morishita, R., Gibbons, G. H., Kaneda, Y., Sato, B. & Dzau, V. J., Jul 1996, In : Journal of Molecular and Cellular Cardiology. 28, 7, p. 1385-1399 15 p.

Research output: Contribution to journalArticle

28 Scopus citations

GABAA receptor subunit mRNA expression in cultured embryonic and adult human dorsal root ganglion neurons

Maddox, F. N., Valeyev, A. Y., Poth, K., Holohean, A. M., Wood, P. M., Davidoff, R. A., Hackman, J. C. & Luetje, C. W., Apr 19 2004, In : Developmental Brain Research. 149, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

GADD45γ: A new vitamin D-regulated gene that is antiproliferative in prostate cancer cells

Flores, O. & Burnstein, K. L., Oct 2010, In : Endocrinology. 151, 10, p. 4654-4664 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain

Huang, W., Kazmierczak, K., Zhou, Z., Aguiar-Pulido, V., Narasimhan, G. & Szczesna-Cordary, D., Jul 1 2016, In : Archives of Biochemistry and Biophysics. 601, p. 121-132 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

General linearized biexponential model for QSAR data showing bilinear-type distribution

Buchwald, P., Nov 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2355-2379 25 p.

Research output: Contribution to journalArticle

28 Scopus citations

Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy

Wang, Y., Pinto, J. R., Solis, R. S., Dweck, D., Liang, J., Diaz-Perez, Z., Ge, Y., Walker, J. W. & Potter, J. D., Jan 13 2012, In : Journal of Biological Chemistry. 287, 3, p. 2156-2167 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury

Dvoriantchikova, G., Ivanov, D., Barakat, D., Grinberg, A., Wen, R., Slepak, V. Z. & Shestopalov, V. I., Feb 23 2012, In : PloS one. 7, 2, e31991.

Research output: Contribution to journalArticle

73 Scopus citations

Genetic elucidation of human hyperosmia to isovaleric acid

Menashe, I., Abaffy, T., Hasin, Y., Goshen, S., Yahalom, V., Luetje, C. W. & Lancet, D., Nov 2007, In : PLoS biology. 5, 11, p. 2462-2468 7 p.

Research output: Contribution to journalArticle

134 Scopus citations

Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites

Parrish, J. Z., Kim, M. D., Lily, Y. J. & Yuh, N. J., Apr 1 2006, In : Genes and Development. 20, 7, p. 820-835 16 p.

Research output: Contribution to journalArticle

150 Scopus citations

Germinal center-specific protein human germinal center associated lymphoma directly interacts with both myosin and actin and increases the binding of myosin to actin

Lu, X., Kazmierczak, K., Jiang, X., Jones, M., Watt, J., Helfman, D. M., Moore, J. R., Szczesna-Cordary, D. & Lossos, I. S., Jun 2011, In : FEBS Journal. 278, 11, p. 1922-1931 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Getting in Touch with the Clathrin Terminal Domain

Lemmon, S. K. & Traub, L. M., Apr 2012, In : Traffic. 13, 4, p. 511-519 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Global Deletion of Trp53 Reverts Ovarian Tumor Phenotype of the Germ Cell–Deficient White Spotting Variant (Wv) Mice

Cai, K. Q., Wang, Y., Smith, E. R., Smedberg, J. L., Yang, D. H., Yang, W. L. & Xu, X. X., Jan 1 2015, In : Neoplasia. 17, 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors

Cornacchia, F., Fornoni, A., Plati, A. R., Thomas, A., Wang, Y., Inverardi, L., Striker, L. J. & Striker, G. E., 2001, In : Journal of Clinical Investigation. 108, 11, p. 1649-1656 8 p.

Research output: Contribution to journalArticle

110 Scopus citations

Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

Buchwald, P., Feb 1 2008, In : Steroids. 73, 2, p. 193-208 16 p.

Research output: Contribution to journalArticle

31 Scopus citations

Glucose-stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets

Buchwald, P., Tamayo-Garcia, A., Manzoli, V., Tomei, A. A. & Stabler, C. L., Jan 2018, In : Biotechnology and Bioengineering. 115, 1, p. 232-245 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Glycosaminoglycan-dependent and -independent inhibition of neurite outgrowth by agrin

Baerwald-De La Torre, K., Winzen, U., Halfter, W. & Bixby, J. L., Jul 1 2004, In : Journal of neurochemistry. 90, 1, p. 50-61 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Glycosylation within the Cystein loop and six residues near conserved Cys192/Cys193 are determinants of neuronal bungarotoxin sensitivity on the neuronal nicotinic receptor α3 subunit

Luetje, C. W., Maddox, F. N. & Harvey, S. C., Jun 1 1998, In : Molecular Pharmacology. 53, 6, p. 1112-1119 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1

Chan, Y. M., Broder-Fingert, S., Paraschos, S., Lapatto, R., Au, M., Hughes, V., Bianco, S. D. C., Min, L., Plummer, L., Cerrato, F., De Guillebon, A., Wu, I. H., Wahab, F., Dwyer, A., Kirsch, S., Quinton, R., Cheetham, T., Ozata, M., Ten, S., Chanoine, J. P. & 8 others, Pitteloud, N., Martin, K. A., Schiffmann, R., Van Der Kamp, H. J., Nader, S., Hall, J. E., Kaiser, U. B. & Seminara, S. B., Nov 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 11, p. E1771-E1781

Research output: Contribution to journalArticle

43 Scopus citations

Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle

Percival, J. M., Anderson, K. N. E., Huang, P., Adams, M. E. & Froehner, S. C., Mar 1 2010, In : Journal of Clinical Investigation. 120, 3, p. 816-826 11 p.

Research output: Contribution to journalArticle

94 Scopus citations

GPCR ontology: Development and application of a G protein-coupled receptor pharmacology knowledge framework

Przydzial, M. J., Bhhatarai, B., Koleti, A., Vempati, U., Schürer, S. C. & Wren, J., Dec 15 2013, In : Bioinformatics. 29, 24, p. 3211-3219 9 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

G-protein inhibition of phospholipase C-β1 in membranes: Role of G-protein βγ subunits

Litosch, I., 1996, In : Biochemical Journal. 319, 1, p. 173-178 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

G protein-mediated inhibition of phospholipase C activity in a solubilized membrane preparation

Litosch, I., Sulkholutskaya, I. & Weng, C., Jan 1 1993, In : Journal of Biological Chemistry. 268, 12, p. 8692-8697 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
22 Scopus citations

G-protein βγ subunits antagonize protein kinase C-dependent phosphorylation and inhibition of phospholipase C-β1

Litosch, I., Sep 15 1997, In : Biochemical Journal. 326, 3, p. 701-707 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Growth cone pathfinding and filopodial dynamics are mediated separately by Cdc42 activation

Kim, M. D., Kolodziej, P. & Chiba, A., Mar 1 2002, In : Journal of Neuroscience. 22, 5, p. 1794-1806 13 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Growth cone steering by receptor tyrosine phosphatase δ defines a distinct class of guidance cue

Sun, Q. L., Wang, J., Bookman, R. J. & Bixby, J. L., Jan 1 2000, In : Molecular and Cellular Neuroscience. 16, 5, p. 686-695 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine With subacute ischemic cardiomyopathy

Bagno, L. L., Kanashiro-Takeuchi, R. M., Suncion, V. Y., Golpanian, S., Karantalis, V., Wolf, A., Wang, B., Premer, C., Balkan, W., Rodriguez, J., Valdes, D., Rosado, M., Block, N. L., Goldstein, P., Morales, A., Cai, R. Z., Sha, W., Schally, A. V. & Hare, J. M., 2015, In : Journal of the American Heart Association. 4, 4, e001464.

Research output: Contribution to journalArticle

12 Scopus citations

GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation

Penas, C., Mishra, J. K., Wood, S. D., Schürer, S. C., Roush, W. R. & Ayad, N. G., Feb 1 2015, In : Cell Cycle. 14, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

GSK3 involvement in amylin signaling in isolated rat soleus muscle

Abaffy, T. & Cooper, G. J. S., Dec 1 2004, In : Peptides. 25, 12, p. 2119-2125 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
11 Scopus citations
61 Scopus citations

Guanine nucleotides mediate stimulatory and inhibitory effects on cerebral-cortical membrane phospholipase C activity

Litosch, I., 1989, In : Biochemical Journal. 261, 1, p. 245-251 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Gα16, a G protein α subunit specifically expressed in hematopoietic cells

Amatruda, T. T., Steele, D. A., Slepak, V. Z. & Simon, M. I., 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 13, p. 5587-5591 5 p.

Research output: Contribution to journalArticle

Open Access
228 Scopus citations
82 Scopus citations

Gβ5-RGS7 inhibits Gαq-mediated signaling via a direct protein-protein interaction

Witherow, D. S., Tovey, S. C., Wang, Q., Willars, G. B. & Slepak, V. Z., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 21307-21313 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

H6, a novel hederagenin derivative, reverses multidrug resistance in vitro and in vivo

Yang, Y., Guan, D., Lei, L., Lu, J., Liu, J. Q., Yang, G., Yan, C., Zhai, R., Tian, J., Bi, Y., Fu, F. & Wang, H., Feb 15 2018, In : Toxicology and Applied Pharmacology. 341, p. 98-105 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex

Karpinsky-Semper, D., Tayou, J., Levay, K., Schuchardt, B. J., Bhat, V., Volmar, C. H., Farooq, A. & Slepak, V. Z., Feb 3 2015, In : Biochemistry. 54, 4, p. 1077-1088 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis

Hu, X., Zhang, L., Jin, J., Zhu, W., Xu, Y., Wu, Y., Wang, Y., Chen, H., Webster, K. A., Chen, H., Yu, H. & Wang, J., Jun 1 2015, In : Stem Cells. 33, 6, p. 1850-1862 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Hepatocyte growth factor and vitamin D cooperatively inhibit androgen-unresponsive prostate cancer cell lines

Qadan, L. R., Perez-Stable, C. M., Schwall, R. H., Burnstein, K. L., Ostenson, R. C., Howard, G. A. & Roos, B. A., Jan 1 2000, In : Endocrinology. 141, 7, p. 2567-2573 7 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Hepatoma-derived growth factor-related protein-3 is a novel angiogenic factor

LeBlanc, M. E., Wang, W., Caberoy, N. B., Chen, X., Guo, F., Alvarado, G., Shen, C., Wang, F., Wang, H., Chen, R., Liu, Z. J., Webster, K. & Li, W., May 21 2015, In : PloS one. 10, 5, e0127904.

Research output: Contribution to journalArticle

11 Scopus citations

Heterogeneity in SDF-1 expression defines the vasculogenic potential of adult cardiac progenitor cells

Rodrigues, C. O., Shehadeh, L. A., Hoosien, M., Otero, V., Chopra, I., Tsinoremas, N. F. & Bishopric, N. H., Aug 24 2011, In : PloS one. 6, 8, e24013.

Research output: Contribution to journalArticle

11 Scopus citations