Molecular and Cellular Pharmacology

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2003

The actin-regulating kinase Prk1p negatively regulates Scd5p, a suppressor of clathrin deficiency, in actin organization and endocytosis

Henry, K. R., D'Hondt, K., Chang, J. S., Nix, D. A., Cope, M. J. T. V., Chan, C. S. M., Drubin, D. G. & Lemmon, S., Sep 2 2003, In : Current Biology. 13, 17, p. 1564-1569 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

The kelch repeat protein, Tea1, is a potential substrate target of the p21-activated kinase, Shk1, in the fission yeast, Schizosaccharomyces pombe

Kim, H., Yang, P., Catanuto, P., Verde, F., Lai, H., Du, H., Chang, F. & Marcus, S., Aug 8 2003, In : Journal of Biological Chemistry. 278, 32, p. 30074-30082 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Therapeutic Angiogenesis: A Complex Problem Requiring a Sophisticated Approach

Webster, K. A., Oct 31 2003, In : Cardiovascular Toxicology. 3, 3, p. 283-297 15 p.

Research output: Contribution to journalArticle

22 Scopus citations

Tyrosine Phosphorylation of Rod Cyclic Nucleotide-Gated Channels Switches Off Ca2+/Calmodulin Inhibition

Krajewski, J. L., Luetje, C. W. & Kramer, R. H., Nov 5 2003, In : Journal of Neuroscience. 23, 31, p. 10100-10106 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
111 Scopus citations
2002

25-Hydroxyvitamin D-1α-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer

Whitlatch, L. W., Young, M. V., Schwartz, G. G., Flanagan, J. N., Burnstein, K. L., Lokeshwar, B. L., Rich, E. S., Holick, M. F. & Chen, T. C., Aug 23 2002, In : Journal of Steroid Biochemistry and Molecular Biology. 81, 2, p. 135-140 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress

Dougherty, C. J., Kubasiak, L. A., Prentice, H., Andreka, P., Bishopric, N. & Webster, K. A., Mar 15 2002, In : Biochemical Journal. 362, 3, p. 561-571 11 p.

Research output: Contribution to journalArticle

148 Scopus citations
22 Scopus citations

Barriers to remember: Brain-targeting chemical delivery systems and Alzheimer's disease

Bodor, N. & Buchwald, P., Jul 1 2002, In : Drug Discovery Today. 7, 14, p. 766-774 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Bucindolol displays intrinsic sympathomimetic activity in human myocardium

Andreka, P., Aiyar, N., Olson, L. C., Wei, J., Turner, M. S., Webster, K. A., Ohlstein, E. H. & Bishopric, N., May 21 2002, In : Circulation. 105, 20, p. 2429-2434 6 p.

Research output: Contribution to journalArticle

61 Scopus citations
25 Scopus citations

Effects of pyridine ring substitutions on affinity, efficacy, and subtype selectivity of neuronal nicotinic receptor agonist epibatidine

Avalos, M., Parker, M. J., Maddox, F. N., Ivy Carroll, F. & Luetje, C. W., Sep 1 2002, In : Journal of Pharmacology and Experimental Therapeutics. 302, 3, p. 1246-1252 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Gene and cell therapy for heart disease

Graham, R. M., Bishopric, N. & Webster, K. A., Aug 1 2002, In : IUBMB Life. 54, 2, p. 59-66 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3

Kubasiak, L. A., Hernandez, O. M., Bishopric, N. & Webster, K. A., Oct 1 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 20, p. 12825-12830 6 p.

Research output: Contribution to journalArticle

346 Scopus citations

Modulation of neuronal nicotinic acetylcholine receptors by mercury

Mirzoian, A. & Luetje, C. W., Jul 30 2002, In : Journal of Pharmacology and Experimental Therapeutics. 302, 2, p. 560-567 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Phosphorylation of the regulatory light chains of myosin affects Ca2+ sensitivity of skeletal muscle contraction

Szczesna-Cordary, D., Zhao, J., Jones, M., Zhi, G., Stull, J. & Potter, J. D., Jul 3 2002, In : Journal of Applied Physiology. 92, 4, p. 1661-1670 10 p.

Research output: Contribution to journalArticle

73 Scopus citations

Physicochemical aspects of the enzymatic hydrolysis of carboxylic esters

Buchwald, P. & Bodor, N., Feb 26 2002, In : Pharmazie. 57, 2, p. 87-93 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Preventing apoptosis with thioredoxin: ASK me how

Bishopric, N. & Webster, K. A., Jun 28 2002, In : Circulation Research. 90, 12, p. 1237-1239 3 p.

Research output: Contribution to journalArticle

17 Scopus citations

SHP-2 mediates target-regulated axonal termination and NGF-dependent neurite growth in sympathetic neurons

Chen, B., Hammonds-Odie, L., Perron, J., Masters, B. A. & Bixby, J., Dec 1 2002, In : Developmental Biology. 252, 2, p. 170-187 18 p.

Research output: Contribution to journalArticle

14 Scopus citations

Signal-dependent translocation of transducin, RGS9-1-Gβ5L complex, and arrestin to detergent-resistant membrane rafts in photoreceptors

Nair, K. S., Balasubramanian, N. & Slepak, V. Z., Mar 5 2002, In : Current Biology. 12, 5, p. 421-425 5 p.

Research output: Contribution to journalArticle

93 Scopus citations

Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats

Hausmann, O. N., Hu, W. H., Keren-Raifman, T., Witherow, D. S., Wang, Q., Levay, K., Frydel, B., Slepak, V. Z. & Bethea, J. R., Dec 31 2002, In : European Journal of Neuroscience. 15, 4, p. 602-612 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Theoretical insights into the formation, structure, and energetics of some cyclodextrin complexes

Bodor, N. & Buchwald, P., Dec 1 2002, In : Journal of Inclusion Phenomena. 44, 1-4, p. 9-14 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

The role of troponin in the Ca(2+)-regulation of skeletal muscle contraction.

Szczesna-Cordary, D. & Potter, J. D., Mar 14 2002, In : Results and Problems in Cell Differentiation. 36, p. 171-190 20 p.

Research output: Contribution to journalArticle

12 Scopus citations

The role of troponins in muscle contraction

Gomes, A. V., Potter, J. D. & Szczesna-Cordary, D., Dec 1 2002, In : IUBMB Life. 54, 6, p. 323-333 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

Vitamin D-mediated growth inhibition of an androgen-ablated LNCaP cell line model of human prostate cancer

Yang, E. S., Maiorino, C. A., Roos, B. A., Knight, S. R. & Burnstein, K. L., Jan 15 2002, In : Molecular and Cellular Endocrinology. 186, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

36 Scopus citations
2001

Abnormal Contractile Function in Transgenic Mice Expressing a Familial Hypertrophic Cardiomyopathy-linked Troponin T (I79N) Mutation

Miller, T., Szczesna-Cordary, D., Housmans, P. R., Zhao, J., De Freitas, F., Gomes, A. V., Culbreath, L., McCue, J., Wang, Y., Xu, Y., Kerrick, W. G. & Potter, J. D., Feb 9 2001, In : Journal of Biological Chemistry. 276, 6, p. 3743-3755 13 p.

Research output: Contribution to journalArticle

91 Scopus citations

Attempts of ranking in a series of synthetic nonpsychotropic cannabinoids.

Pop, E. & Buchwald, P., Jan 1 2001, In : SAR and QSAR in Environmental Research. 12, 1-2, p. 113-127 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

BMP growth factors and Phox2 transcription factors can induce synaptotagmin I and neurexin I during sympathetic neuron development

Patzke, H., Reissmann, E., Stanke, M., Bixby, J. & Ernsberger, U., Oct 11 2001, In : Mechanisms of Development. 108, 1-2, p. 149-159 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cell polarity: A tale of two Ts

Verde, F., Aug 7 2001, In : Current Biology. 11, 15

Research output: Contribution to journalArticle

6 Scopus citations

Control of Cardiac-specific Transcription by p300 through Myocyte Enhancer Factor-2D

Slepak, T. I., Webster, K. A., Zang, J., Prentice, H., O'Dowd, A., Hicks, M. N. & Bishopric, N., Mar 9 2001, In : Journal of Biological Chemistry. 276, 10, p. 7575-7585 11 p.

Research output: Contribution to journalArticle

57 Scopus citations

CRYP-2/cPTPRO is a neurite inhibitory repulsive guidance cue for retinal neurons in vitro

Stepanek, L., Sun, Q. L., Wang, J., Wang, C. & Bixby, J., Aug 20 2001, In : Journal of Cell Biology. 154, 4, p. 867-878 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis

Andreka, P., Zang, J., Dougherty, C., Slepak, T. I., Webster, K. A. & Bishopric, N., Feb 16 2001, In : Circulation Research. 88, 3, p. 305-312 8 p.

Research output: Contribution to journalArticle

112 Scopus citations

Determinants of agonist binding affinity on neuronal nicotinic receptor β subunits

Parker, M. J., Harvey, S. C. & Luetje, C. W., Oct 9 2001, In : Journal of Pharmacology and Experimental Therapeutics. 299, 1, p. 385-391 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Expression levels of RGS7 and RGS4 proteins determine the mode of regulation of the G protein-activated K+ channel and control regulation of RGS7 by Gβ5

Keren-Raifman, T., Bera, A. K., Zveig, D., Peleg, S., Witherow, D. S., Slepak, V. Z. & Dascal, N., Mar 9 2001, In : FEBS Letters. 492, 1-2, p. 20-28 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Expression of RFG/ELE1α/ARA70 in normal and malignant prostatic epithelial cell cultures and lines: Regulation by methylation and sex steroids

Tekur, S., Lau, K. M., Long, J., Burnstein, K. L. & Ho, S. M., Feb 19 2001, In : Molecular Carcinogenesis. 30, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Familial Hypertrophic Cardiomyopathy Mutations in the Regulatory Light Chains of Myosin Affect their Structure, Ca2+ Binding, and Phosphorylation

Szczesna-Cordary, D., Ghosh, D., Li, Q., Gomes, A. V., Guzman, G., Arana, C., Zhi, G., Stull, J. T. & Potter, J. D., Mar 9 2001, In : Journal of Biological Chemistry. 276, 10, p. 7086-7092 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors

Cornacchia, F., Fornoni, A., Plati, A. R., Thomas, A., Wang, Y., Inverardi, L. A., Striker, L. J. & Striker, G. E., Dec 29 2001, In : Journal of Clinical Investigation. 108, 11, p. 1649-1656 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

Ligands and signaling through receptor-type tyrosine phosphatases

Bixby, J., Sep 12 2001, In : IUBMB Life. 51, 3, p. 157-163 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP

Yamashita, K., Discher, D. J., Hu, J., Bishopric, N. & Webster, K. A., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 12645-12653 9 p.

Research output: Contribution to journalArticle

261 Scopus citations

Oxidation of zinc finger transcription factors: Physiological consequences

Webster, K. A., Prentice, H. & Bishopric, N., Sep 6 2001, In : Antioxidants and Redox Signaling. 3, 4, p. 535-548 14 p.

Research output: Contribution to journalArticle

107 Scopus citations

Phosphorylation of the regulator of G protein signaling RGS9-1 by protein kinase a is a potential mechanism of light- and Ca2+-mediated regulation of G protein function in photoreceptors

Balasubramanian, N., Levay, K., Keren-Raifman, T., Faurobert, E. & Slepak, V. Z., Oct 23 2001, In : Biochemistry. 40, 42, p. 12619-12627 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Reperfusion-activated Akt kinase prevents apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1

Yamashita, K., Kajstura, J., Discher, D. J., Wasserlauf, B. J., Bishopric, N., Anversa, P. & Webster, K. A., Mar 30 2001, In : Circulation Research. 88, 6, p. 609-614 6 p.

Research output: Contribution to journalArticle

122 Scopus citations
86 Scopus citations
31 Scopus citations

Subunit-dependent modulation of neuronal nicotinic receptors by zinc

Hsiao, B., Dweck, D. & Luetje, C. W., Mar 15 2001, In : Journal of Neuroscience. 21, 6, p. 1848-1856 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

The androgen receptor (AR) amino-terminus imposes androgen-specific regulation of AR gene expression via an exonic enhancer

Grad, J. M., Lyons, L. S., Robins, D. M. & Burnstein, K. L., Mar 20 2001, In : Endocrinology. 142, 3, p. 1107-1116 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

The Highly Conserved Protein Methyltransferase, Skb1, Is a Mediator of Hyperosmotic Stress Response in the Fission Yeast Schizosaccharomyces pombe

Bao, S., Qyang, Y., Yang, P., Kim, H., Du, H., Bartholomeusz, G., Henkel, J., Pimental, R., Verde, F. & Marcus, S., May 4 2001, In : Journal of Biological Chemistry. 276, 18, p. 14549-14552 4 p.

Research output: Contribution to journalArticle

34 Scopus citations

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

De Jesus, L. A., Carvalho, S. D., Ribeiro, M. O., Schneider, M., Kim, S. W., Harney, J. W., Larsen, P. R. & Bianco, A. C., Dec 13 2001, In : Journal of Clinical Investigation. 108, 9, p. 1379-1385 7 p.

Research output: Contribution to journalArticle

316 Scopus citations

Thyroid hormone-sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform-specific

Ribeiro, M. O., Carvalho, S. D., Schultz, J. J., Chiellini, G., Scanlan, T. S., Bianco, A. C. & Brent, G. A., Jul 24 2001, In : Journal of Clinical Investigation. 108, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

190 Scopus citations

Type 2 iodothyronine deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis

Pachucki, J., Hopkins, J., Peeters, R., Tu, H., Carvalho, S. D., Kaulbach, H., Dale Abel, E., Wondisford, F. E., Ingwall, J. S. & Reed Larsen, P., Mar 12 2001, In : Endocrinology. 142, 1, p. 13-20 8 p.

Research output: Contribution to journalArticle

54 Scopus citations