Molecular and Cellular Pharmacology

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2005

P-type proton ATPases are involved in intracellular calcium and proton uptake in the plant parasite Phytomonas francai

Miranda, K., Vercesi, A. E., Catisti, R., De Souza, W., Rodrigues, C. O. & Docampo, R., Feb 2005, In : Journal of Eukaryotic Microbiology. 52, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
10 Scopus citations

RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation

Cheng, L., Lemmon, S. & Lemmon, V., Aug 2005, In : Journal of neurochemistry. 94, 4, p. 1102-1110 9 p.

Research output: Contribution to journalArticle

74 Scopus citations

Receptor tyrosine phosphatases guide vertebrate motor axons during development

Stepanek, L., Stoker, A. W., Stoeckli, E. & Bixby, J. L., Apr 13 2005, In : Journal of Neuroscience. 25, 15, p. 3813-3823 11 p.

Research output: Contribution to journalArticle

74 Scopus citations

Synthesis and pharmacological effects of new, N-substituted soft anticholinergics based on glycopyrrolate

Ji, F., Wu, W., Dai, X., Mori, N., Wu, J., Buchwald, P. & Bodor, N., Dec 1 2005, In : Journal of Pharmacy and Pharmacology. 57, 11, p. 1427-1435 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice

Szczesna-Cordary, D., Guzman, G., Zhao, J., Hernandez, O., Wei, J. & Diaz-Perez, Z., Aug 15 2005, In : Journal of Cell Science. 118, 16, p. 3675-3683 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

The miscommunicative cardiac cell: When good proteins go bad

Gomes, A. V., Venkatraman, G. & Potter, J. D., Jan 1 2005, In : Annals of the New York Academy of Sciences. 1047, p. 30-37 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

The presence of a Leu-Gly-Asn repeat-enriched protein (LGN), a putative binding partner of transducin, in ROD photoreceptors

Nair, K. S., Mendez, A., Blumer, J. B., Rosenzweig, D. H. & Slepak, V. Z., Jan 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 1, p. 383-389 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila

Hiesinger, P. R., Fayyazuddin, A., Mehta, S. Q., Rosenmund, T., Schulze, K. L., Zhai, R. G., Verstreken, P., Cao, Y., Zhou, Y., Kunz, J. & Bellen, H. J., May 20 2005, In : Cell. 121, 4, p. 607-620 14 p.

Research output: Contribution to journalArticle

226 Scopus citations

Unified pharmacogenetics-based parent-metabolite pharmacokinetic model incorporating acetylation polymorphism for talampanel in humans

Buchwald, P., Juhász, A., Bell, C., Pátfalusi, M., Howes, J. & Bodor, N., Aug 1 2005, In : Journal of Pharmacokinetics and Pharmacodynamics. 32, 3-4, p. 377-400 24 p.

Research output: Contribution to journalArticle

5 Scopus citations
2004

Acidocalcisomes of Phytomonas françai possess distinct morphological characteristics and contain iron

Miranda, K., Rodrigues, C. O., Hentchel, J., Vercesi, A., Plattner, H., De Souza, W. & Docampo, R., Oct 2004, In : Microscopy and Microanalysis. 10, 5, p. 647-655 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

A New Luciferase Reporter Gene Assay for the Detection of Androgenic and Antiandrogenic Effects Based on a Human Prostate Specific Antigen Promoter and PC3/AR Human Prostate Cancer Cells

Kizu, R., Otsuki, N., Kishida, Y., Toriba, A., Mizokami, A., Burnstein, K. L., Klinge, C. M. & Hayakawa, K., Jan 2004, In : Analytical Sciences. 20, 1, p. 55-59 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

A novel RING-finger-like protein Ini1 is essential for cell cycle progression in fission yeast

Oltra, E., Verde, F., Werner, R. & D'Urso, G., Feb 29 2004, In : Journal of Cell Science. 117, 6, p. 967-974 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Antiandrogenic activity of extracts of diesel exhaust particles emitted from diesel-engine truck under different engine loads and speeds

Okamura, K., Kizu, R., Toriba, A., Murahashi, T., Mizokami, A., Burnstein, K. L., Klinge, C. M. & Hayakawa, K., Feb 15 2004, In : Toxicology. 195, 2-3, p. 243-254 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Cardiac troponin T isoforms affect the Ca2+ sensitivity of force development in the presence of slow skeletal troponin I: Insights into the role of troponin T isoforms in the fetal heart

Gomes, A. V., Venkatraman, G., Davis, J. P., Tikunova, S. B., Engel, P., Solaro, R. J. & Potter, J. D., Nov 26 2004, In : Journal of Biological Chemistry. 279, 48, p. 49579-49587 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Cellular and molecular aspects of familial hypertrophic cardiomyopathy caused by mutations in the cardiac troponin I gene

Gomes, A. V. & Potter, J. D., Aug 1 2004, In : Molecular and Cellular Biochemistry. 263, 1, p. 99-114 16 p.

Research output: Contribution to journalArticle

52 Scopus citations

Chronic cardiac-specific thyrotoxicosis increases myocardial β-adrenergic responsiveness

Carvalho-Bianco, S. D., Kim, B. W., Zhang, J. X., Harney, J. W., Ribeiro, R. S., Gereben, B., Bianco, A. C., Mende, U. & Larsen, P. R., Jul 2004, In : Molecular Endocrinology. 18, 7, p. 1840-1849 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21CIP1 levels in androgen-independent human prostate cancer cells

Knight-Krajewski, S., Welsh, C. F., Liu, Y., Lyons, L. S., Faysal, J. M., Yang, E. S. & Burnstein, K. L., Jul 15 2004, In : Oncogene. 23, 32, p. 5513-5522 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Determinants of Potency on α-Conotoxin MII, a Peptide Antagonist of Neuronal Nicotinic Receptors

Everhart, D., Cartier, G. E., Malhotra, A., Gomes, A. V., McIntosh, J. M. & Luetje, C. W., Mar 16 2004, In : Biochemistry. 43, 10, p. 2732-2737 6 p.

Research output: Contribution to journalArticle

42 Scopus citations

Direct binding of visual arrestin to microtubules determines the differential subcellular localization of its splice variants in rod photoreceptors

Nair, K. S., Hanson, S. M., Kennedy, M. J., Hurley, J. B., Gurevich, V. V. & Slepak, V. Z., Sep 24 2004, In : Journal of Biological Chemistry. 279, 39, p. 41240-41248 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

Endograft technology: A delivery vehicle for intravascular gene therapy

Eton, D., Yu, H., Wang, Y., Raines, J., Striker, G., Livingstone, A. & Baxter, T., May 2004, In : Journal of vascular surgery. 39, 5, p. 1066-1073 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
52 Scopus citations
62 Scopus citations

GABAA receptor subunit mRNA expression in cultured embryonic and adult human dorsal root ganglion neurons

Maddox, F. N., Valeyev, A. Y., Poth, K., Holohean, A. M., Wood, P. M., Davidoff, R. A., Hackman, J. C. & Luetje, C. W., Apr 19 2004, In : Developmental Brain Research. 149, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Glycosaminoglycan-dependent and -independent inhibition of neurite outgrowth by agrin

Baerwald-De La Torre, K., Winzen, U., Halfter, W. & Bixby, J. L., Jul 1 2004, In : Journal of neurochemistry. 90, 1, p. 50-61 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

GSK3 involvement in amylin signaling in isolated rat soleus muscle

Abaffy, T. & Cooper, G. J. S., Dec 1 2004, In : Peptides. 25, 12, p. 2119-2125 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification and cloning of two putative subunits of DNA polymerase epsilon in fussion yeast

Spiga, M. G. & D'Urso, G., 2004, In : Nucleic acids research. 32, 16, p. 4945-4953 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Metabolic properties of phosphonate esters

Somogyi, G., Buchwald, P. & Bodor, N., May 1 2004, In : Pharmazie. 59, 5, p. 378-381 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mice with Targeted Disruption of the Dio2 Gene Have Cold-Induced Overexpression of the Uncoupling Protein 1 Gene but Fail to Increase Brown Adipose Tissue Lipogenesis and Adaptive Thermogenesis

Christoffolete, M. A., Linardi, C. C. G., De Jesus, L., Ebina, K. N., Carvalho, S. D., Ribeiro, M. O., Rabelo, R., Curcio, C., Martins, L., Kimura, E. T. & Bianco, A. C., Mar 1 2004, In : Diabetes. 53, 3, p. 577-584 8 p.

Research output: Contribution to journalArticle

143 Scopus citations

Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation

Dougherty, C. J., Kubasiak, L. A., Frazier, D. P., Li, H., Xiong, W. C., Bishopric, N. H. & Webster, K. A., Jul 1 2004, In : FASEB Journal. 18, 10, p. 1060-1070 11 p.

Research output: Contribution to journalArticle

83 Scopus citations

Molecular and cellular aspects of troponin cardiomyopathies

Gomes, A. V. & Potter, J. D., Jan 1 2004, In : Annals of the New York Academy of Sciences. 1015, p. 214-224 11 p.

Research output: Contribution to journalArticle

84 Scopus citations

Nitric oxide and promotion of cardiac myocyte apoptosis

Andréka, P., Tran, T., Webster, K. A. & Bishopric, N. H., Aug 1 2004, In : Molecular and Cellular Biochemistry. 263, 1, p. 35-53 19 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pancreatic cancer cells express 25-hydroxyvitamin D-1α-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3

Schwartz, G. G., Eads, D., Rao, A., Cramer, S. D., Willingham, M. C., Chen, T. C., Jamieson, D. P., Wang, L., Burnstein, K. L., Holick, M. F. & Koumenis, C., Jun 1 2004, In : Carcinogenesis. 25, 6, p. 1015-1026 12 p.

Research output: Contribution to journalArticle

88 Scopus citations

Regulation of a formin complex by the microtubule plus end protein tea1p

Feierbach, B., Verde, F. & Chang, F., Jun 7 2004, In : Journal of Cell Biology. 165, 5, p. 697-707 11 p.

Research output: Contribution to journalArticle

97 Scopus citations

Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels

Turner, M. S., Haywood, G. A., Andreka, P., You, L., Martin, P. E., Evans, W. H., Webster, K. A. & Bishopric, N. H., Oct 1 2004, In : Circulation research. 95, 7, p. 726-733 8 p.

Research output: Contribution to journalArticle

62 Scopus citations

Soft glucocorticoid design: Structural elements and physicochemical parameters determining receptor-binding affinity

Buchwald, P. & Bodor, N., May 1 2004, In : Pharmazie. 59, 5, p. 396-404 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Targeting of a Tropomyosin Isoform to Short Microfilaments Associated with the Golgi Complex

Percival, J. M., Hughes, J. A. I., Brown, D. L., Schevzov, G., Heimann, K., Vrhovski, B., Bryce, N., Stow, J. L. & Gunning, P. W., Jan 2004, In : Molecular biology of the cell. 15, 1, p. 268-280 13 p.

Research output: Contribution to journalArticle

73 Scopus citations

Variation in the antiandrogenic activity of diesel exhaust particulates emitted under different engine loads

Okamura, K., Kizu, R., Hayakawa, K., Toriba, A., Mizokami, A., Burnstein, K. L., Klinge, C. M. & Kato, S., Aug 1 2004, In : Polycyclic Aromatic Compounds. 24, 4-5, p. 743-757 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
2003

Adenylyl cyclase expression and modulation of cAMP in rat taste cells

Abaffy, T., Trubey, K. R. & Chaudhari, N., Jun 1 2003, In : American Journal of Physiology - Cell Physiology. 284, 6 53-6, p. C1420-C1428

Research output: Contribution to journalArticle

43 Scopus citations

Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells

Kizu, R., Okamura, K., Toriba, A., Mizokami, A., Burnstein, K. L., Klinge, C. M. & Hayakawa, K., Dec 1 2003, In : Toxicological Sciences. 76, 2, p. 299-309 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

A role of aryl hydrocarbon receptor in the antiandrogenic effects of polycyclic aromatic hydrocarbons in LNCaP human prostate carcinoma cells

Kizu, R., Okamura, K., Toriba, A., Kakishima, H., Mizokami, A., Burnstein, K. L. & Hayakawa, K., Jun 1 2003, In : Archives of Toxicology. 77, 6, p. 335-343 9 p.

Research output: Contribution to journalArticle

89 Scopus citations

Characterization of Tescalcin, a Novel EF-Hand Protein with a Single Ca2+-Binding Site: Metal-Binding Properties, Localization in Tissues and Cells, and Effect on Calcineurin

Gutierrez-Ford, C., Levay, K., Gomes, A. V., Perera, E. M., Som, T., Kim, Y. M., Benovic, J. L., Berkovitz, G. D. & Slepak, V. Z., Dec 16 2003, In : Biochemistry. 42, 49, p. 14553-14565 13 p.

Research output: Contribution to journalArticle

49 Scopus citations

Control of Cell Polarity in Fission Yeast by Association of Orb6p Kinase with the Highly Conserved Protein Methyltransferase Skb1p

Wiley, D. J., Marcus, S., D'Urso, G. & Verde, F., Jul 4 2003, In : Journal of Biological Chemistry. 278, 27, p. 25256-25263 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Different Functional Properties of Troponin T Mutants that Cause Dilated Cardiomyopathy

Venkatraman, G., Harada, K., Gomes, A. V., Kerrick, W. G. L. & Potter, J. D., Oct 24 2003, In : Journal of Biological Chemistry. 278, 43, p. 41670-41676 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Direct, differential-equation-based in-vitro-in-vivo correlation (IVIVC) method

Buchwald, P., Apr 1 2003, In : Journal of Pharmacy and Pharmacology. 55, 4, p. 495-504 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Evaluation of vitamin D analogs as therapeutic agents for prostate cancer.

Chen, T. C., Holick, M. F., Lokeshwar, B. L., Burnstein, K. L. & Schwartz, G. G., 2003, In : Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer. 164, p. 273-288 16 p.

Research output: Contribution to journalArticle

31 Scopus citations

Expression of PTPRO during mouse development suggests involvement in axonogenesis and differentiation of NT-3 and NGF-dependent neurons

Beltran, P. J., Bixby, J. L. & Masters, B. A., Feb 17 2003, In : Journal of Comparative Neurology. 456, 4, p. 384-395 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling

Knollmann, B. C., Kirchhof, P., Sirenko, S. G., Degen, H., Greene, A. E., Schober, T., Mackow, J. C., Fabritz, L., Potter, J. D. & Morad, M., Mar 7 2003, In : Circulation research. 92, 4, p. 428-436 9 p.

Research output: Contribution to journalArticle

111 Scopus citations

Gβ5-RGS7 inhibits Gαq-mediated signaling via a direct protein-protein interaction

Witherow, D. S., Tovey, S. C., Wang, Q., Willars, G. B. & Slepak, V. Z., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 21307-21313 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors

Everhart, D., Reiller, E., Mirzoian, A., McIntosh, J. M., Malhotra, A. & Luetje, C. W., Aug 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 306, 2, p. 664-670 7 p.

Research output: Contribution to journalArticle

31 Scopus citations