Molecular and Cellular Pharmacology

Research Output

Filter
Article
2006

Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast

Newpher, T. M. & Lemmon, S. K., May 2006, In : Traffic. 7, 5, p. 574-588 15 p.

Research output: Contribution to journalArticle

47 Scopus citations

Cortical recruitment and nuclear-cytoplasmic shuttling of Scd5p, a protein phosphatase-1-targeting protein involved in actin organization and endocytosis

Chang, J. S., Henry, K., Geli, M. I. & Lemmon, S. K., Jan 2006, In : Molecular biology of the cell. 17, 1, p. 251-262 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Determinants of zinc potentiation on the α4 subunit of neuronal nicotinic receptors

Hsiao, B., Mihalak, K. B., Repicky, S. E., Everhart, D., Mederos, A. H., Malhotra, A. & Luetje, C. W., Jan 2006, In : Molecular Pharmacology. 69, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Determinants of α-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor β subunit

Shiembob, D. L., Roberts, R. L., Luetje, C. W. & McIntosh, J. M., Sep 19 2006, In : Biochemistry. 45, 37, p. 11200-11207 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Differences in the glucocorticoid to the progesterone receptor selectivity of inhaled glucocorticoids

Issar, M., Sahasranaman, S., Buchwald, P. & Hochhaus, G., Mar 1 2006, In : European Respiratory Journal. 27, 3, p. 511-516 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
14 Scopus citations

Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts - Role of myofilament Ca2+ sensitivity increase

Sirenko, S. G., Potter, J. D. & Knollmann, B. C., Aug 1 2006, In : Journal of Physiology. 575, 1, p. 201-213 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Diltiazem treatment prevents diastolic heart failure in mice with familial hypertrophic cardiomyopathy

Westermann, D., Knollmann, B. C., Steendijk, P., Rutschow, S., Riad, A., Pauschinger, M., Potter, J. D., Schultheiss, H. P. & Tschöpe, C., Mar 1 2006, In : European Journal of Heart Failure. 8, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

Zhai, R. G., Cao, Y., Hiesinger, P. R., Zhou, Y., Mehta, S. Q., Schulze, K. L., Verstreken, P. & Bellen, H. J., Dec 2006, In : PLoS biology. 4, 12, p. 2336-2348 13 p.

Research output: Contribution to journalArticle

127 Scopus citations

E22K mutation of RLC that causes familial hypertrophic cardiomyopathy in heterozygous mouse myocardium: Effect on cross-bridge kinetics

Dumka, D., Talent, J., Akopova, I., Guzman, G., Szczesna-Cordary, D. & Borejdo, J., Nov 24 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 291, 5, p. H2098-H2106

Research output: Contribution to journalArticle

9 Scopus citations

Functional analysis of a mammalian odorant receptor subfamily

Abaffy, T., Matsunami, H. & Luetje, C. W., Jun 1 2006, In : Journal of neurochemistry. 97, 5, p. 1506-1518 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites

Parrish, J. Z., Kim, M. D., Lily, Y. J. & Yuh, N. J., Apr 1 2006, In : Genes and Development. 20, 7, p. 820-835 16 p.

Research output: Contribution to journalArticle

150 Scopus citations

Hydration of the folding transition state ensemble of a protein

Brun, L., Isom, D. G., Velu, P., García-Moreno, B. & Royer, C. A., Mar 21 2006, In : Biochemistry. 45, 11, p. 3473-3480 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Incidence of heart failure in infarcted rats that die spontaneously

Flumignan, R. L. G., Kanashiro, R. M., Saraiva, R. M., Portes, L. A., Antonio, E. L., Ishigai, M. M. S. & Tucci, P. J. F., Oct 2006, In : Brazilian Journal of Medical and Biological Research. 39, 10, p. 1323-1328 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Influence of the N-acetylation polymorphism on the metabolism of talampanel: An investigation in fasted and fed subjects genotyped for NAT2 variants

Buchwald, P., Juhász, A., Bell, C., Pátfalusi, M., Kovács, P., Hochhaus, G., Howes, J. & Bodor, N., Feb 1 2006, In : Pharmazie. 61, 2, p. 125-134 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Irreversible aggregation of protein synthesis machinery after focal brain ischemia

Zhang, F., Liu, C. L. & Hu, B. R., Jul 1 2006, In : Journal of neurochemistry. 98, 1, p. 102-112 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Novel function of clathrin light chain in promoting endocytic vesicle formation

Newpher, T. M., Idrissi, F. Z., Geli, M. I. & Lemmon, S. K., Oct 2006, In : Molecular biology of the cell. 17, 10, p. 4343-4352 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Performance of two-dimensional Doppler echocardiography for the assessment of infarct size and left ventricular function in rats

Nozawa, E., Kanashiro, R. M., Murad, N., Carvalho, A. C. C., Cravo, S. L. D., Campos, O., Tucci, P. J. F. & Moises, V. A., May 2006, In : Brazilian Journal of Medical and Biological Research. 39, 5, p. 687-695 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Pharmacological effects of some newly developed soft anticholinergics and a receptor-binding QSAR study

Mori, N., Buchwald, P., Wu, W. M., Ji, F., Hochhaus, G. & Bodor, N., Feb 1 2006, In : Pharmazie. 61, 2, p. 148-153 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prolonged Ca2+ and Force Transients in Myosin RLC Transgenic Mouse Fibers Expressing Malignant and Benign FHC Mutations

Wang, Y., Xu, Y., Kerrick, W. G. L., Wang, Y., Guzman, G., Diaz-Perez, Z. & Szczesna-Cordary, D., Aug 11 2006, In : Journal of molecular biology. 361, 2, p. 286-299 14 p.

Research output: Contribution to journalArticle

47 Scopus citations
16 Scopus citations

Structural basis for calcium-induced inhibition of rhodopsin kinase by recoverin

Ames, J. B., Levay, K., Wingard, J. N., Lusin, J. D. & Slepak, V. Z., Dec 1 2006, In : Journal of Biological Chemistry. 281, 48, p. 37237-37245 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Structural determinants for phosphatidic acid regulation of phospholipase C-β1

Ross, E. M., Mateu, D., Gomes, A. V., Arana, C., Tran, T. & Litosch, I., Nov 3 2006, In : Journal of Biological Chemistry. 281, 44, p. 33087-33094 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

The bHLH-PAS protein spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons

Kim, M. D., Lily, Y. J. & Yuh, N. J., Oct 15 2006, In : Genes and Development. 20, 20, p. 2806-2819 14 p.

Research output: Contribution to journalArticle

85 Scopus citations

The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast

Locovei, A. M., Spiga, M. G., Tanaka, K., Murakami, Y. & D'Urso, G., Nov 17 2006, In : Cell Division. 1, 27.

Research output: Contribution to journalArticle

10 Scopus citations
15 Scopus citations

Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptors

Mihalak, K. B., Carroll, F. I. & Luetje, C. W., Aug 28 2006, In : Molecular Pharmacology. 70, 3, p. 801-805 5 p.

Research output: Contribution to journalArticle

427 Scopus citations
54 Scopus citations
2005
45 Scopus citations
22 Scopus citations

Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle

Gounis, M. J., Spiga, M. G., Graham, R. M., Wilson, A., Haliko, S., Lieber, B. B., Wakhloo, A. K. & Webster, K. A., May 1 2005, In : Gene Therapy. 12, 9, p. 762-771 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth

Chen, B. & Bixby, J. L., Feb 26 2005, In : Journal of Neuroscience. 25, 4, p. 880-888 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform

Venkatraman, G., Gomes, A. V., Kerrick, W. G. L. & Potter, J. D., May 6 2005, In : Journal of Biological Chemistry. 280, 18, p. 17584-17592 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Co-translational protein aggregation after transient cerebral ischemia

Liu, C. L., Ge, P., Zhang, F. & Hu, B. R., Sep 5 2005, In : Neuroscience. 134, 4, p. 1273-1284 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: A new intracellular target for matrix metalloproteinase-2

Sawicki, G., Leon, H., Sawicka, J., Sariahmetoglu, M., Schulze, C. J., Scott, P. G., Szczesna-Cordary, D. & Schulz, R., Jul 26 2005, In : Circulation. 112, 4, p. 544-552 9 p.

Research output: Contribution to journalArticle

207 Scopus citations

Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein

Cho, H. M., Rosenblatt, J. D., Kang, Y. S., Iruela-Arispe, M. L., Morrison, S. L., Penichet, M. L., Kwon, Y. G., Kim, T. W., Webster, K. A., Nechustan, H. & Shin, S. U., Jun 1 2005, In : Molecular cancer therapeutics. 4, 6, p. 956-967 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Expanding the range of free calcium regulation in biological solutions

Dweck, D., Reyes-Alfonso, A. & Potter, J. D., Dec 15 2005, In : Analytical Biochemistry. 347, 2, p. 303-315 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

Expression of neuronal markers suggests heterogeneity of chick sympathoadrenal cells prior to invasion of the adrenal anlagen

Ernsberger, U., Esposito, L., Partimo, S., Huber, K., Franke, A., Bixby, J. L., Kalcheim, C. & Unsicker, K., Jan 1 2005, In : Cell and Tissue Research. 319, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers

Hernandez, O. M., Szczesna-Cordary, D., Knollmann, B. C., Miller, T., Bell, M., Zhao, J., Sirenko, S. G., Diaz, Z., Guzman, G., Xu, Y., Wang, Y., Kerrick, W. G. L. & Potter, J. D., Nov 4 2005, In : Journal of Biological Chemistry. 280, 44, p. 37183-37194 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis

Kanai, M., Kume, K., Miyahara, K., Sakai, K., Nakamura, K., Leonhard, K., Wiley, D. J., Verde, F., Toda, T. & Hirata, D., Sep 2005, In : EMBO Journal. 24, 17, p. 3012-3025 14 p.

Research output: Contribution to journalArticle

55 Scopus citations

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in α-tropomyosin

Chang, A. N., Harada, K., Ackerman, M. J. & Potter, J. D., Oct 7 2005, In : Journal of Biological Chemistry. 280, 40, p. 34343-34349 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

General linearized biexponential model for QSAR data showing bilinear-type distribution

Buchwald, P., Nov 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2355-2379 25 p.

Research output: Contribution to journalArticle

28 Scopus citations

In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast

Newpher, T. M., Smith, R. P., Lemmon, V. & Lemmon, S. K., Jul 1 2005, In : Developmental Cell. 9, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

143 Scopus citations

Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions

Nair, K. S., Hanson, S. M., Mendez, A., Gurevich, E. V., Kennedy, M. J., Shestopalov, V. I., Vishnivetskiy, S. A., Chen, J., Hurley, J. B., Gurevich, V. V. & Slepak, V. Z., May 19 2005, In : Neuron. 46, 4, p. 555-567 13 p.

Research output: Contribution to journalArticle

143 Scopus citations

Modest actomyosin energy conservation increases myocardial postischemic function

Blunt, B. C., Chen, Y., Potter, J. D. & Hofmann, P. A., Mar 1 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 288, 3 57-3, p. H1088-H1096

Research output: Contribution to journalArticle

6 Scopus citations

Motor neurite outgrowth is selectively inhibited by cell surface MuSK and agrin

Dimitropoulou, A. & Bixby, J. L., Feb 2005, In : Molecular and Cellular Neuroscience. 28, 2, p. 292-302 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components

Mehta, S. Q., Hiesinger, P. R., Beronja, S., Zhai, R. G., Schulze, K. L., Verstreken, P., Cao, Y., Zhou, Y., Tepass, U., Crair, M. C. & Bellen, H. J., Apr 21 2005, In : Neuron. 46, 2, p. 219-232 14 p.

Research output: Contribution to journalArticle

108 Scopus citations

Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force development

Gomes, A. V., Liang, J. & Potter, J. D., Sep 2 2005, In : Journal of Biological Chemistry. 280, 35, p. 30909-30915 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Neuronal pentraxin with chromo domain (NPCD) is a novel class of protein expressed in multiple neuronal domains

Chen, B. & Bixby, J. L., Jan 24 2005, In : Journal of Comparative Neurology. 481, 4, p. 391-402 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics

Wu, W. M., Buchwald, P., Mori, N., Ji, F., Wu, J. X. & Bodor, N., Dec 1 2005, In : Pharmaceutical Research. 22, 12, p. 2035-2044 10 p.

Research output: Contribution to journalArticle

7 Scopus citations