Molecular and Cellular Pharmacology

Research Output

Filter
Article
2006

Irreversible aggregation of protein synthesis machinery after focal brain ischemia

Zhang, F., Liu, C. L. & Hu, B. R., Jul 1 2006, In : Journal of neurochemistry. 98, 1, p. 102-112 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Novel function of clathrin light chain in promoting endocytic vesicle formation

Newpher, T. M., Idrissi, F. Z., Geli, M. I. & Lemmon, S. K., Oct 1 2006, In : Molecular biology of the cell. 17, 10, p. 4343-4352 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Performance of two-dimensional Doppler echocardiography for the assessment of infarct size and left ventricular function in rats

Nozawa, E., Kanashiro, R. M., Murad, N., Carvalho, A. C. C., Cravo, S. L. D., Campos, O., Tucci, P. J. F. & Moises, V. A., May 1 2006, In : Brazilian Journal of Medical and Biological Research. 39, 5, p. 687-695 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Pharmacological effects of some newly developed soft anticholinergics and a receptor-binding QSAR study

Mori, N., Buchwald, P., Wu, W. M., Ji, F., Hochhaus, G. & Bodor, N., Feb 1 2006, In : Pharmazie. 61, 2, p. 148-153 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prolonged Ca2+ and Force Transients in Myosin RLC Transgenic Mouse Fibers Expressing Malignant and Benign FHC Mutations

Wang, Y., Xu, Y., Kerrick, W. G. L., Wang, Y., Guzman, G., Diaz-Perez, Z. & Szczesna-Cordary, D., Aug 11 2006, In : Journal of molecular biology. 361, 2, p. 286-299 14 p.

Research output: Contribution to journalArticle

47 Scopus citations
15 Scopus citations

Structural basis for calcium-induced inhibition of rhodopsin kinase by recoverin

Ames, J. B., Levay, K., Wingard, J. N., Lusin, J. D. & Slepak, V. Z., Dec 1 2006, In : Journal of Biological Chemistry. 281, 48, p. 37237-37245 9 p.

Research output: Contribution to journalArticle

74 Scopus citations

Structural determinants for phosphatidic acid regulation of phospholipase C-β1

Ross, E. M., Mateu, D., Gomes, A. V., Arana, C., Tran, T. & Litosch, I., Nov 3 2006, In : Journal of Biological Chemistry. 281, 44, p. 33087-33094 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

The bHLH-PAS protein spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons

Kim, M. D., Lily, Y. J. & Yuh, N. J., Oct 15 2006, In : Genes and Development. 20, 20, p. 2806-2819 14 p.

Research output: Contribution to journalArticle

84 Scopus citations

The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast

Locovei, A. M., Spiga, M. G., Tanaka, K., Murakami, Y. & D'Urso, G., Nov 17 2006, In : Cell Division. 1, 27.

Research output: Contribution to journalArticle

9 Scopus citations
14 Scopus citations

Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptors

Mihalak, K. B., Carroll, F. I. & Luetje, C. W., Aug 28 2006, In : Molecular Pharmacology. 70, 3, p. 801-805 5 p.

Research output: Contribution to journalArticle

412 Scopus citations
53 Scopus citations

γ-Syntrophin scaffolding is spatially and functionally distinct from that of the α/β syntrophins

Alessi, A., Bragg, A. D., Percival, J. M., Yoo, J., Albrecht, D. E., Froehner, S. C. & Adams, M. E., Oct 1 2006, In : Experimental Cell Research. 312, 16, p. 3084-3095 12 p.

Research output: Contribution to journalArticle

28 Scopus citations
2005
45 Scopus citations
21 Scopus citations

Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle

Gounis, M. J., Spiga, M. G., Graham, R. M., Wilson, A., Haliko, S., Lieber, B. B., Wakhloo, A. K. & Webster, K. A., May 1 2005, In : Gene Therapy. 12, 9, p. 762-771 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth

Chen, B. & Bixby, J. L., Feb 26 2005, In : Journal of Neuroscience. 25, 4, p. 880-888 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

A routine electrocardiogram should not be used to determine the size of myocardial infarction in the rat

Bonilha, A. M. M., Saraiva, R. M., Kanashiro, R. M., Portes, L. A., Antonio, E. L. & Tucci, P. J. F., Apr 2005, In : Brazilian Journal of Medical and Biological Research. 38, 4, p. 615-619 5 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform

Venkatraman, G., Gomes, A. V., Kerrick, W. G. L. & Potter, J. D., May 6 2005, In : Journal of Biological Chemistry. 280, 18, p. 17584-17592 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Co-translational protein aggregation after transient cerebral ischemia

Liu, C. L., Ge, P., Zhang, F. & Hu, B. R., Sep 5 2005, In : Neuroscience. 134, 4, p. 1273-1284 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: A new intracellular target for matrix metalloproteinase-2

Sawicki, G., Leon, H., Sawicka, J., Sariahmetoglu, M., Schulze, C. J., Scott, P. G., Szczesna-Cordary, D. & Schulz, R., Jul 26 2005, In : Circulation. 112, 4, p. 544-552 9 p.

Research output: Contribution to journalArticle

203 Scopus citations

Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein

Cho, H. M., Rosenblatt, J. D., Kang, Y. S., Iruela-Arispe, M. L., Morrison, S. L., Penichet, M. L., Kwon, Y. G., Kim, T. W., Webster, K. A., Nechustan, H. & Shin, S. U., Jun 1 2005, In : Molecular cancer therapeutics. 4, 6, p. 956-967 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Expanding the range of free calcium regulation in biological solutions

Dweck, D., Reyes-Alfonso, A. & Potter, J. D., Dec 15 2005, In : Analytical Biochemistry. 347, 2, p. 303-315 13 p.

Research output: Contribution to journalArticle

58 Scopus citations

Expression of neuronal markers suggests heterogeneity of chick sympathoadrenal cells prior to invasion of the adrenal anlagen

Ernsberger, U., Esposito, L., Partimo, S., Huber, K., Franke, A., Bixby, J. L., Kalcheim, C. & Unsicker, K., Jan 1 2005, In : Cell and Tissue Research. 319, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers

Hernandez, O. M., Szczesna-Cordary, D., Knollmann, B. C., Miller, T., Bell, M., Zhao, J., Sirenko, S. G., Diaz, Z., Guzman, G., Xu, Y., Wang, Y., Kerrick, W. G. L. & Potter, J. D., Nov 4 2005, In : Journal of Biological Chemistry. 280, 44, p. 37183-37194 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis

Kanai, M., Kume, K., Miyahara, K., Sakai, K., Nakamura, K., Leonhard, K., Wiley, D. J., Verde, F., Toda, T. & Hirata, D., Sep 1 2005, In : EMBO Journal. 24, 17, p. 3012-3025 14 p.

Research output: Contribution to journalArticle

55 Scopus citations

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in α-tropomyosin

Chang, A. N., Harada, K., Ackerman, M. J. & Potter, J. D., Oct 7 2005, In : Journal of Biological Chemistry. 280, 40, p. 34343-34349 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

General linearized biexponential model for QSAR data showing bilinear-type distribution

Buchwald, P., Nov 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2355-2379 25 p.

Research output: Contribution to journalArticle

27 Scopus citations

In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast

Newpher, T. M., Smith, R. P., Lemmon, V. & Lemmon, S. K., Jul 1 2005, In : Developmental Cell. 9, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

139 Scopus citations

Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions

Nair, K. S., Hanson, S. M., Mendez, A., Gurevich, E. V., Kennedy, M. J., Shestopalov, V. I., Vishnivetskiy, S. A., Chen, J., Hurley, J. B., Gurevich, V. V. & Slepak, V. Z., May 19 2005, In : Neuron. 46, 4, p. 555-567 13 p.

Research output: Contribution to journalArticle

143 Scopus citations

Listeria's right-handed helical rocket-tail trajectories: Mechanistic implications for force generation in actin-based motility

Zeile, W. L., Zhang, F., Dickinson, R. B. & Purich, D. L., Feb 1 2005, In : Cell Motility and the Cytoskeleton. 60, 2, p. 121-128 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Modest actomyosin energy conservation increases myocardial postischemic function

Blunt, B. C., Chen, Y., Potter, J. D. & Hofmann, P. A., Mar 1 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 288, 3 57-3, p. H1088-H1096

Research output: Contribution to journalArticle

6 Scopus citations

Motor neurite outgrowth is selectively inhibited by cell surface MuSK and agrin

Dimitropoulou, A. & Bixby, J. L., Feb 2005, In : Molecular and Cellular Neuroscience. 28, 2, p. 292-302 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components

Mehta, S. Q., Hiesinger, P. R., Beronja, S., Zhai, R. G., Schulze, K. L., Verstreken, P., Cao, Y., Zhou, Y., Tepass, U., Crair, M. C. & Bellen, H. J., Apr 21 2005, In : Neuron. 46, 2, p. 219-232 14 p.

Research output: Contribution to journalArticle

106 Scopus citations

Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force development

Gomes, A. V., Liang, J. & Potter, J. D., Sep 2 2005, In : Journal of Biological Chemistry. 280, 35, p. 30909-30915 7 p.

Research output: Contribution to journalArticle

79 Scopus citations

Neuronal pentraxin with chromo domain (NPCD) is a novel class of protein expressed in multiple neuronal domains

Chen, B. & Bixby, J. L., Jan 24 2005, In : Journal of Comparative Neurology. 481, 4, p. 391-402 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics

Wu, W. M., Buchwald, P., Mori, N., Ji, F., Wu, J. X. & Bodor, N., Dec 1 2005, In : Pharmaceutical Research. 22, 12, p. 2035-2044 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Prospective exploration of synthetically feasible, medicinally relevant chemical space

Schürer, S. C., Tyagi, P. & Muskal, S. M., Mar 1 2005, In : Journal of Chemical Information and Modeling. 45, 2, p. 239-248 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

P-type proton ATPases are involved in intracellular calcium and proton uptake in the plant parasite Phytomonas francai

Miranda, K., Vercesi, A. E., Catisti, R., De Souza, W., Rodrigues, C. O. & Docampo, R., Feb 1 2005, In : Journal of Eukaryotic Microbiology. 52, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
10 Scopus citations

RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation

Cheng, L., Lemmon, S. & Lemmon, V., Aug 1 2005, In : Journal of neurochemistry. 94, 4, p. 1102-1110 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Receptor tyrosine phosphatases guide vertebrate motor axons during development

Stepanek, L., Stoker, A. W., Stoeckli, E. & Bixby, J. L., Apr 13 2005, In : Journal of Neuroscience. 25, 15, p. 3813-3823 11 p.

Research output: Contribution to journalArticle

74 Scopus citations

Synthesis and pharmacological effects of new, N-substituted soft anticholinergics based on glycopyrrolate

Ji, F., Wu, W., Dai, X., Mori, N., Wu, J., Buchwald, P. & Bodor, N., Dec 1 2005, In : Journal of Pharmacy and Pharmacology. 57, 11, p. 1427-1435 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice

Szczesna-Cordary, D., Guzman, G., Zhao, J., Hernandez, O., Wei, J. & Diaz-Perez, Z., Aug 15 2005, In : Journal of Cell Science. 118, 16, p. 3675-3683 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

The miscommunicative cardiac cell: When good proteins go bad

Gomes, A. V., Venkatraman, G. & Potter, J. D., Jan 1 2005, In : Annals of the New York Academy of Sciences. 1047, p. 30-37 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

The presence of a Leu-Gly-Asn repeat-enriched protein (LGN), a putative binding partner of transducin, in ROD photoreceptors

Nair, K. S., Mendez, A., Blumer, J. B., Rosenzweig, D. H. & Slepak, V. Z., Jan 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 1, p. 383-389 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila

Hiesinger, P. R., Fayyazuddin, A., Mehta, S. Q., Rosenmund, T., Schulze, K. L., Zhai, R. G., Verstreken, P., Cao, Y., Zhou, Y., Kunz, J. & Bellen, H. J., May 20 2005, In : Cell. 121, 4, p. 607-620 14 p.

Research output: Contribution to journalArticle

220 Scopus citations

Unified pharmacogenetics-based parent-metabolite pharmacokinetic model incorporating acetylation polymorphism for talampanel in humans

Buchwald, P., Juhász, A., Bell, C., Pátfalusi, M., Howes, J. & Bodor, N., Aug 1 2005, In : Journal of Pharmacokinetics and Pharmacodynamics. 32, 3-4, p. 377-400 24 p.

Research output: Contribution to journalArticle

5 Scopus citations
2004

Acidocalcisomes of Phytomonas françai possess distinct morphological characteristics and contain iron

Miranda, K., Rodrigues, C. O., Hentchel, J., Vercesi, A., Plattner, H., De Souza, W. & Docampo, R., Oct 1 2004, In : Microscopy and Microanalysis. 10, 5, p. 647-655 9 p.

Research output: Contribution to journalArticle

20 Scopus citations