Molecular and Cellular Pharmacology

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2008

Troponin and cardiomyopathy

Chang, A. N., Parvatiyar, M. S. & Potter, J. D., Apr 25 2008, In : Biochemical and biophysical research communications. 369, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
42 Scopus citations

Zinc potentiates neuronal nicotinic receptors by increasing burst duration

Hsiao, B., Mihalak, K. B., Magleby, K. L. & Luetje, C. W., Feb 1 2008, In : Journal of neurophysiology. 99, 2, p. 999-1007 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2007

A general bilinear model to describe growth or decline time profiles

Buchwald, P., Jan 1 2007, In : Mathematical Biosciences. 205, 1, p. 108-136 29 p.

Research output: Contribution to journalArticle

27 Scopus citations

A honey bee odorant receptor for the queen substance 9-oxo-2-decenoic acid

Wanner, K. W., Nichols, A. S., Walden, K. K. O., Brockmann, A., Luetje, C. W. & Robertson, H. M., Sep 4 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 36, p. 14383-14388 6 p.

Research output: Contribution to journalArticle

125 Scopus citations

Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their Activity

Hanson, S. M., Cleghorn, W. M., Francis, D. J., Vishnivetskiy, S. A., Raman, D., Song, X., Nair, K. S., Slepak, V. Z., Klug, C. S. & Gurevich, V. V., Apr 27 2007, In : Journal of molecular biology. 368, 2, p. 375-387 13 p.

Research output: Contribution to journalArticle

83 Scopus citations

Coping with cyclic oxygen availability: Evolutionary aspects

Flück, M., Webster, K. A., Graham, J., Giomi, F., Gerlach, F. & Schmitz, A., Oct 1 2007, In : Integrative and comparative biology. 47, 4, p. 524-531 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Fast skeletal muscle regulatory light chain is required for fast and slow skeletal muscle development

Wang, Y., Szczesna-Cordary, D., Craig, R., Diaz-Perez, Z., Guzman, G., Miller, T. & Potter, J. D., Jul 2007, In : FASEB Journal. 21, 9, p. 2205-2214 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

From critters to cancers: Bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

Hoogewijs, D., Terwilliger, N. B., Webster, K. A., Powell-Coffman, J. A., Tokishita, S., Yamagata, H., Hankeln, T., Burmester, T., Rytknen, K. T., Nikinmaa, M., Abele, D., Heise, K., Lucassen, M., Fandrey, J., Maxwell, P. H., Phlman, S. & Gorr, T. A., Oct 1 2007, In : Integrative and comparative biology. 47, 4, p. 552-577 26 p.

Research output: Contribution to journalArticle

19 Scopus citations

Genetic elucidation of human hyperosmia to isovaleric acid

Menashe, I., Abaffy, T., Hasin, Y., Goshen, S., Yahalom, V., Luetje, C. W. & Lancet, D., Nov 1 2007, In : PLoS biology. 5, 11, p. 2462-2468 7 p.

Research output: Contribution to journalArticle

131 Scopus citations

Increased expression of cyclin B1 sensitizes prostate cancer cells to apoptosis induced by chemotherapy

Gomez, L. A., De Las Pozas, A., Reiner, T., Burnstein, K. & Perez-Stable, C., May 1 2007, In : Molecular cancer therapeutics. 6, 5, p. 1534-1543 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Intramolecular interaction between the DEP domain of RGS7 and the Gβ5 subunit

Narayanan, V., Sandiford, S. L., Wang, Q., Keren-Raifman, T., Levay, K. & Slepak, V. Z., Jun 12 2007, In : Biochemistry. 46, 23, p. 6859-6870 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Involvement of endoplasmic reticulum stress in a novel Classic Galactosemia model

Slepak, T. I., Tang, M., Slepak, V. Z. & Lai, K., Sep 1 2007, In : Molecular Genetics and Metabolism. 92, 1-2, p. 78-87 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Jun kinase delays caspase-9 activation by interaction with the apoptosome

Tran, T. H., Andreka, P., Rodrigues, C. O., Webster, K. A. & Bishopric, N. H., Jul 13 2007, In : Journal of Biological Chemistry. 282, 28, p. 20340-20350 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene

Bianco, S. D. C., Peng, J. B., Takanaga, H., Suzuki, Y., Crescenzi, A., Kos, C. H., Zhuang, L., Freeman, M. R., Gouveia, C. H. A., Wu, J., Luo, H., Mauro, T., Brown, E. M. & Hediger, M. A., Feb 1 2007, In : Journal of Bone and Mineral Research. 22, 2, p. 274-285 12 p.

Research output: Contribution to journalArticle

193 Scopus citations

Myocyte deficiency as a target in the treatment of cardiomyopathy

Rodrigues, C. O., Shehadeh, L. A., Webster, K. A. & Bishopric, N. H., Sep 1 2007, In : Progress in Pediatric Cardiology. 23, 1-2, p. 49-59 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients

Szczesna-Cordary, D., Jones, M., Moore, J. R., Watt, J., Kerrick, W. G. L., Xu, Y., Wang, Y., Wagg, C. & Lopaschuk, G. D., Dec 1 2007, In : FASEB Journal. 21, 14, p. 3974-3985 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Novel, cell-penetrating molecular transporters with flexible backbones and permanently charged side-chains

Bodor, N., Tóth-Sarudy, É., Holm, T., Pallagi, I., Vass, E., Buchwald, P. & Langel, Ü., Aug 1 2007, In : Journal of Pharmacy and Pharmacology. 59, 8, p. 1065-1076 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Parvalbumin isoforms differentially accelerate cardiac myocyte relaxation kinetics in an animal model of diastolic dysfunction

Rodenbaugh, D. W., Wang, W., Davis, J., Edwards, T., Potter, J. D. & Metzger, J. M., Sep 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 293, 3, p. H1705-H1713

Research output: Contribution to journalArticle

16 Scopus citations

PKC-α and TAK-1 are intermediates in the activation of c-Jun NH 2-terminal kinase by hypoxia-reoxygenation

Frazier, D. P., Wilson, A., Dougherty, C. J., Li, H., Bishopric, N. H. & Webster, K. A., Apr 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 4, p. H1675-H1684

Research output: Contribution to journalArticle

25 Scopus citations

rAAV6-Microdystrophin rescues aberrant Golgi complex organization in mdx skeletal muscles

Percival, J. M., Gregorevic, P., Odom, G. L., Banks, G. B., Chamberlain, J. S. & Froehner, S. C., Oct 1 2007, In : Traffic. 8, 10, p. 1424-1439 16 p.

Research output: Contribution to journalArticle

37 Scopus citations

Rats with high left ventricular end-diastolic pressure can be identified by Doppler echocardiography one week after myocardial infarction

Saraiva, R. M., Kanashiro-Takeuchi, R. M., Antonio, E. L., Campos, O., Tucci, P. J. F. & Moisés, V. A., Nov 1 2007, In : Brazilian Journal of Medical and Biological Research. 40, 11, p. 1557-1565 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Regulation of Bnip3 death pathways by calcium, phosphorylation, and hypoxia-reoxygenation

Graham, R. M., Thompson, J. W., Wei, J., Bishopric, N. H. & Webster, K. A., Sep 1 2007, In : Antioxidants and Redox Signaling. 9, 9, p. 1309-1315 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Regulation of cell diameter, For3p localization, and cell symmetry by fission yeast Rho-GAP Rga4p

Das, M., Wiley, D. J., Medina, S., Vincent, H. A., Larrea, M., Oriolo, A. & Verde, F., Jun 1 2007, In : Molecular biology of the cell. 18, 6, p. 2090-2101 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Subunit dissociation and diffusion determine the subcellular localization of rod and cone transducins

Rosenzweig, D. H., Saidas Nair, K., Wei, J., Wang, Q., Garwin, G., Saari, J. C., Chen, C. K., Smrcka, A. V., Swaroop, A., Lem, J., Hurley, J. B. & Slepak, V. Z., May 16 2007, In : Journal of Neuroscience. 27, 20, p. 5484-5494 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expression

Levay, K. & Slepak, V. Z., Sep 4 2007, In : Journal of Clinical Investigation. 117, 9, p. 2672-2683 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model

Layman, H., Spiga, M. G., Brooks, T., Pham, S., Webster, K. A. & Andreopoulos, F. M., Jun 1 2007, In : Biomaterials. 28, 16, p. 2646-2654 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

The molecular basis for ligand specificity in a mouse olfactory receptor: A network of functionally important residues

Abaffy, T., Malhotra, A. & Luetje, C. W., Jan 12 2007, In : Journal of Biological Chemistry. 282, 2, p. 1216-1224 9 p.

Research output: Contribution to journalArticle

78 Scopus citations

The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation

Da-Silva, W. S., Harney, J. W., Kim, B. W., Li, J., Bianco, S. D. C., Crescenzi, A., Christoffolete, M. A., Huang, S. A. & Bianco, A. C., Mar 1 2007, In : Diabetes. 56, 3, p. 767-776 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

Triadins modulate intracellular Ca2+ homeostasis but are not essential for excitation-contraction coupling in skeletal muscle

Shen, X., Franzini-Armstrong, C., Lopez, J. R., Jones, L. R., Kobayashi, Y. M., Wang, Y., Kerrick, W. G. L., Caswell, A. H., Potter, J. D., Miller, T., Allen, P. D. & Perez, C. F., Dec 28 2007, In : Journal of Biological Chemistry. 282, 52, p. 37864-37874 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Vi -value analysis: A pressure-based method for mapping the folding transition state ensemble of proteins

Mitra, L., Hata, K., Kono, R., Maeno, A., Isom, D., Rouget, J. B., Winter, R., Akasaka, K., García-Moreno, B. & Royer, C. A., Nov 21 2007, In : Journal of the American Chemical Society. 129, 46, p. 14108-14109 2 p.

Research output: Contribution to journalArticle

28 Scopus citations
2006

96-Well electroporation method for transfection of mammalian central neurons

Buchser, W. J., Pardinas, J. R., Shi, Y., Bixby, J. L. & Lemmon, V. P., Nov 1 2006, In : BioTechniques. 41, 5, p. 619-624 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Acidosis regulates the stability, hydrophobicity, and activity of the BH3-only protein Bnip3

Frazier, D. P., Wilson, A., Graham, R. M., Thompson, J. W., Bishopric, N. H. & Webster, K. A., Sep 1 2006, In : Antioxidants and Redox Signaling. 8, 9-10, p. 1625-1634 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Activity-Independent Prespecification of Synaptic Partners in the Visual Map of Drosophila

Hiesinger, P. R., Zhai, R. G., Zhou, Y., Koh, T. W., Mehta, S. Q., Schulze, K. L., Cao, Y., Verstreken, P., Clandinin, T. R., Fischbach, K. F., Meinertzhagen, I. A. & Bellen, H. J., Sep 19 2006, In : Current Biology. 16, 18, p. 1835-1843 9 p.

Research output: Contribution to journalArticle

67 Scopus citations

Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast

Newpher, T. M. & Lemmon, S. K., May 1 2006, In : Traffic. 7, 5, p. 574-588 15 p.

Research output: Contribution to journalArticle

47 Scopus citations

Cortical recruitment and nuclear-cytoplasmic shuttling of Scd5p, a protein phosphatase-1-targeting protein involved in actin organization and endocytosis

Chang, J. S., Henry, K., Geli, M. I. & Lemmon, S. K., Jan 1 2006, In : Molecular biology of the cell. 17, 1, p. 251-262 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Determinants of zinc potentiation on the α4 subunit of neuronal nicotinic receptors

Hsiao, B., Mihalak, K. B., Repicky, S. E., Everhart, D., Mederos, A. H., Malhotra, A. & Luetje, C. W., Jan 1 2006, In : Molecular Pharmacology. 69, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Determinants of α-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor β subunit

Shiembob, D. L., Roberts, R. L., Luetje, C. W. & McIntosh, J. M., Sep 19 2006, In : Biochemistry. 45, 37, p. 11200-11207 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Differences in the glucocorticoid to the progesterone receptor selectivity of inhaled glucocorticoids

Issar, M., Sahasranaman, S., Buchwald, P. & Hochhaus, G., Mar 1 2006, In : European Respiratory Journal. 27, 3, p. 511-516 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
13 Scopus citations

Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts - Role of myofilament Ca2+ sensitivity increase

Sirenko, S. G., Potter, J. D. & Knollmann, B. C., Aug 1 2006, In : Journal of Physiology. 575, 1, p. 201-213 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Diltiazem treatment prevents diastolic heart failure in mice with familial hypertrophic cardiomyopathy

Westermann, D., Knollmann, B. C., Steendijk, P., Rutschow, S., Riad, A., Pauschinger, M., Potter, J. D., Schultheiss, H. P. & Tschöpe, C., Mar 1 2006, In : European Journal of Heart Failure. 8, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

Zhai, R. G., Cao, Y., Hiesinger, P. R., Zhou, Y., Mehta, S. Q., Schulze, K. L., Verstreken, P. & Bellen, H. J., Dec 1 2006, In : PLoS biology. 4, 12, p. 2336-2348 13 p.

Research output: Contribution to journalArticle

124 Scopus citations

E22K mutation of RLC that causes familial hypertrophic cardiomyopathy in heterozygous mouse myocardium: Effect on cross-bridge kinetics

Dumka, D., Talent, J., Akopova, I., Guzman, G., Szczesna-Cordary, D. & Borejdo, J., Nov 24 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 291, 5, p. H2098-H2106

Research output: Contribution to journalArticle

9 Scopus citations

Functional analysis of a mammalian odorant receptor subfamily

Abaffy, T., Matsunami, H. & Luetje, C. W., Jun 1 2006, In : Journal of neurochemistry. 97, 5, p. 1506-1518 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites

Parrish, J. Z., Kim, M. D., Lily, Y. J. & Yuh, N. J., Apr 1 2006, In : Genes and Development. 20, 7, p. 820-835 16 p.

Research output: Contribution to journalArticle

148 Scopus citations

Hydration of the folding transition state ensemble of a protein

Brun, L., Isom, D. G., Velu, P., García-Moreno, B. & Royer, C. A., Mar 21 2006, In : Biochemistry. 45, 11, p. 3473-3480 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Immediate functional effects of left ventricular reduction: A Doppler echocardiographic study in the rat

Kanashiro, R. M., Saraiva, R. M., Alberta, A., Antonio, E. L., Moisés, V. A. & Tucci, P. J. F., Mar 1 2006, In : Journal of cardiac failure. 12, 2, p. 163-169 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Incidence of heart failure in infarcted rats that die spontaneously

Flumignan, R. L. G., Kanashiro, R. M., Saraiva, R. M., Portes, L. A., Antonio, E. L., Ishigai, M. M. S. & Tucci, P. J. F., Oct 1 2006, In : Brazilian Journal of Medical and Biological Research. 39, 10, p. 1323-1328 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Influence of the N-acetylation polymorphism on the metabolism of talampanel: An investigation in fasted and fed subjects genotyped for NAT2 variants

Buchwald, P., Juhász, A., Bell, C., Pátfalusi, M., Kovács, P., Hochhaus, G., Howes, J. & Bodor, N., Feb 1 2006, In : Pharmazie. 61, 2, p. 125-134 10 p.

Research output: Contribution to journalArticle

5 Scopus citations