Molecular and Cellular Pharmacology

Research Output 1974 2019

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Article
2017
6 Citations (Scopus)
Statistical Models
Signal Transduction
Ligands
2 Citations (Scopus)

Cardiac contractility, motor function, and cross-bridge kinetics in N47K-RLC mutant mice

Wang, L., Kazmierczak, K., Yuan, C. C., Yadav, S., Kawai, M. & Szczesna-Cordary, D., Jun 1 2017, In : FEBS Journal. 284, 12, p. 1897-1913 17 p.

Research output: Contribution to journalArticle

Myosins
pioglitazone
Light
Adenosine Diphosphate
Kinetics
4 Citations (Scopus)

Comprehensive metabolomics study to assess longitudinal biochemical changes and potential early biomarkers in nonobese diabetic mice that progress to diabetes

Buchwald, P., Tamayo-Garcia, A., Ramamoorthy, S., Garcia-Contreras, M., Mendez, A. J. & Ricordi, C., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3873-3890 18 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Metabolomics
Biomarkers
Medical problems
Type 1 Diabetes Mellitus
9 Citations (Scopus)

Defining disease, diagnosis, and translational medicine within a homeostatic perturbation paradigm: The National Institutes of Health undiagnosed diseases program experience

Gall, T., Valkanas, E., Bello, C., Markello, T., Adams, C., Bone, W. P., Brandt, A. J., Brazill, J. M., Carmichael, L., Davids, M., Davis, J., Diaz-Perez, Z., Draper, D., Elson, J., Flynn, E. D., Godfrey, R., Groden, C., Hsieh, C. K., Fischer, R., Golas, G. A. & 31 others, Guzman, J., Huang, Y., Kane, M. S., Lee, E., Li, C., Links, A. E., Maduro, V., Malicdan, M. C. V., Malik, F. S., Nehrebecky, M., Park, J., Pemberton, P., Schaffer, K., Simeonov, D., Sincan, M., Smedley, D., Valivullah, Z., Wahl, C., Washington, N., Wolfe, L. A., Xu, K., Zhu, Y., Gahl, W. A., Tifft, C. J., Toro, C., Adams, D. R., He, M., Robinson, P. N., Haendel, M. A., Zhai, R. G. & Boerkoel, C. F., Jan 1 2017, In : Frontiers in Medicine. 4, MAY, 62.

Research output: Contribution to journalArticle

Open Access
Translational Medical Research
National Institutes of Health (U.S.)
Genetic Association Studies
Patient Care
Genotype
13 Citations (Scopus)

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop

Jagodnik, K. M., Koplev, S., Jenkins, S. L., Ohno-Machado, L., Paten, B., Schuerer, S. C., Dumontier, M., Verborgh, R., Bui, A., Ping, P., McKenna, N. J., Madduri, R., Pillai, A. & Ma'ayan, A., Jul 1 2017, In : Journal of Biomedical Informatics. 71, p. 49-57 9 p.

Research output: Contribution to journalArticle

Biomedical Research
Education
Information Dissemination
Ecosystem
Research Personnel
8 Citations (Scopus)

Drug target ontology to classify and integrate drug discovery data

Lin, Y., Mehta, S., Küçük-McGinty, H., Turner, J. P., Vidovic, D., Forlin, M., Koleti, A., Nguyen, D. T., Jensen, L. J., Guha, R., Mathias, S. L., Ursu, O., Stathias, V., Duan, J., Nabizadeh, N., Chung, C., Mader, C., Visser, U. E., Yang, J. J., Bologa, C. G. & 2 others, Oprea, T. I. & Schuerer, S. C., Nov 9 2017, In : Journal of Biomedical Semantics. 8, 1, 50.

Research output: Contribution to journalArticle

Drug Discovery
Ontology
Pharmaceutical Preparations
Proteins
Genes
61 Citations (Scopus)

Enhanced cardioprotection by human endometrium mesenchymal stem cells driven by exosomal MicroRNA-21

Wang, K., Jiang, Z., Webster, K. A., Chen, J., Hu, H., Zhou, Y., Zhao, J., Wang, L., Wang, Y., Zhong, Z., Ni, C., Li, Q., Xiang, C., Zhang, L., Wu, R., Zhu, W., Yu, H., Hu, X. & Wang, JA., Jan 1 2017, In : Stem cells translational medicine. 6, 1, p. 209-222 14 p.

Research output: Contribution to journalArticle

Endometrium
MicroRNAs
Mesenchymal Stromal Cells
Bone Marrow
Cell- and Tissue-Based Therapy
6 Citations (Scopus)

From flamingo dance to (desirable) drug discovery: A nature-inspired approach

Sánchez-Rodríguez, A., Pérez-Castillo, Y., Schuerer, S. C., Nicolotti, O., Mangiatordi, G. F., Borges, F., Cordeiro, M. N. D. S., Tejera, E., Medina-Franco, J. L. & Cruz-Monteagudo, M., 2017, (Accepted/In press) In : Drug Discovery Today.

Research output: Contribution to journalArticle

Drug Discovery
Therapeutic Uses
Industry
Pharmaceutical Preparations
Machine Learning
1 Citation (Scopus)

Functional and nonfunctional forms of CquiOR91, an odorant selectivity subunit of Culex quinquefasciatus

Hughes, D. T., Pelletier, J., Rahman, S., Chen, S., Leal, W. S. & Luetje, C. W., May 1 2017, In : Chemical Senses. 42, 4, p. 333-341 9 p., bjx011.

Research output: Contribution to journalArticle

Culex
DEET
Odorant Receptors
Alleles
Ligands
3 Citations (Scopus)

Functional characterizations of rare UBA1 variants in X-linked Spinal Muscular Atrophy

Baumbach-Reardon, L., Balak, C. D., Hunter, J. M., Ahearn, M. E., Wiley, D. & D'urso, G., 2017, In : F1000Research. 6, 1636.

Research output: Contribution to journalArticle

Spinal Muscular Atrophy
Ubiquitin
Mutation
Assays
Missense Mutation
16 Citations (Scopus)

Glucose-stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets

Buchwald, P., Tamayo-Garcia, A., Manzoli, V., Tomei, A. & Stabler, C. L., 2017, (Accepted/In press) In : Biotechnology and Bioengineering.

Research output: Contribution to journalArticle

Hydrogel
Insulin
Islets of Langerhans
Hydrogels
Glucose
10 Citations (Scopus)
Muscle Fatigue
Ryanodine Receptor Calcium Release Channel
Muscle Strength
Muscle
Skeletal Muscle
9 Citations (Scopus)

Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice

Yuan, C. C., Kazmierczak, K., Liang, J., Takeuchi, R., Irving, T. C., Gomes, A. V., Wang, Y., Burghardt, T. P. & Szczesna-Cordary, D., Aug 1 2017, In : Cardiovascular Research. 113, 10, p. 1124-1136 13 p.

Research output: Contribution to journalArticle

Restrictive Cardiomyopathy
Ventricular Myosins
Myosin Light Chains
Myosins
Papillary Muscles
3 Citations (Scopus)

Hypoxic Stress Decreases c-Myc Protein Stability in Cardiac Progenitor Cells Inducing Quiescence and Compromising Their Proliferative and Vasculogenic Potential

Bellio, M. A., Pinto, M. T., Florea, V., Barrios, P. A., Taylor, C. N., Brown, A. B., Lamondin, C., Hare, J., Schulman, I. H. & Rodrigues, C. D., Dec 1 2017, In : Scientific Reports. 7, 1, 9702.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-myc
Protein Stability
Stem Cells
Cell Cycle Resting Phase
Cytoprotection
6 Citations (Scopus)

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

Allen, B. K., Mehta, S., Ember, S. W. J., Zhu, J. Y., Schönbrunn, E., Ayad, N. & Schuerer, S. C., Jan 1 2017, In : ACS Omega. 2, 8, p. 4760-4771 12 p.

Research output: Contribution to journalArticle

Open Access
Screening
Ligands
Proteins
Molecular dynamics
Computer simulation
9 Citations (Scopus)

Identification of miRNAs involved in DRG neurite outgrowth and their putative targets

Motti, D., Lerch, J. K., Danzi, M. C., Gans, J. H., Kuo, F., Slepak, T. I., Bixby, J. & Lemmon, V., 2017, (Accepted/In press) In : FEBS Letters.

Research output: Contribution to journalArticle

Diagnosis-Related Groups
MicroRNAs
Protein Isoforms
Neurites
Neurons
4 Citations (Scopus)

Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit

Kepchia, D., Moliver, S., Chohan, K., Phillips, C. & Luetje, C. W., May 1 2017, In : PLoS One. 12, 5, e0177454.

Research output: Contribution to journalArticle

Odorant Receptors
Insects
antagonists
insects
receptors
4 Citations (Scopus)
Grafts
Scaffolds
Polydimethylsiloxane
Transplants
Islets of Langerhans Transplantation
1 Citation (Scopus)

Loss of c-Kit function impairs arteriogenesis in a mouse model of hindlimb ischemia

Hernandez, D. R., Artiles, A., Duque, J. C., Martinez, L., Pinto, M. T., Webster, K. A., Velazquez, O. C., Vazquez-Padron, R. I. & Soares, R., Jan 1 2017, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journalArticle

Hindlimb
Ischemia
Blood Vessels
Foot
Bone Marrow Transplantation
1 Citation (Scopus)

Mammalian odorant receptor tuning breadth persists across distinct odorant panels

Kepchia, D., Sherman, B., Haddad, R. & Luetje, C. W., Sep 1 2017, In : PLoS One. 12, 9, e0185329.

Research output: Contribution to journalArticle

Odorant Receptors
odor compounds
Tuning
screening
Odors
10 Citations (Scopus)

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Garcia-Contreras, M., Tamayo-Garcia, A., Pappan, K. L., Michelotti, G. A., Stabler, C. L., Ricordi, C. & Buchwald, P., Jun 2 2017, In : Journal of Proteome Research. 16, 6, p. 2294-2306 13 p.

Research output: Contribution to journalArticle

Metabolomics
Islets of Langerhans
Insulin
Inflammation
Glucose
4 Citations (Scopus)

Mutant cycle analysis identifies a ligand interaction site in an odorant receptor of the malaria vector Anopheles gambiae

Rahman, S. & Luetje, C. W., Jan 1 2017, In : Journal of Biological Chemistry. 292, 46, p. 18916-18923 8 p.

Research output: Contribution to journalArticle

Odorant Receptors
Anopheles gambiae
Malaria
Ligands
Insects
16 Citations (Scopus)

Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way

Zhu, J., Lu, K., Zhang, N., Zhao, Y., Ma, Q., Shen, J., Lin, Y., Xiang, P., Tang, Y., Hu, X., Chen, J., Zhu, W., Webster, K. A., Wang, J. & Yu, H., Nov 14 2017, (Accepted/In press) In : Artificial Cells, Nanomedicine and Biotechnology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Exosomes
Sphingomyelin Phosphodiesterase
Cell Hypoxia
Stem cells
MicroRNAs
10 Citations (Scopus)

Nitric Oxide Regulates Skeletal Muscle Fatigue, Fiber Type, Microtubule Organization, and Mitochondrial ATP Synthesis Efficiency Through cGMP-Dependent Mechanisms

Moon, Y., Balke, J. E., Madorma, D., Siegel, M. P., Knowels, G., Brouckaert, P., Buys, E. S., Marcinek, D. J. & Percival, J., Jun 10 2017, In : Antioxidants and Redox Signaling. 26, 17, p. 966-985 20 p.

Research output: Contribution to journalArticle

Muscle Fatigue
Guanylate Cyclase
Skeletal Muscle Fibers
Microtubules
Muscle
5 Citations (Scopus)

Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses

Ong, E., Xie, J., Ni, Z., Liu, Q., Sarntivijai, S., Lin, Y., Cooper, D., Terryn, R., Stathias, V., Chung, C., Schuerer, S. C. & He, Y., Dec 21 2017, In : BMC Bioinformatics. 18, 556.

Research output: Contribution to journalArticle

Libraries
Signature
Cells
Cell Line
Line
40 Citations (Scopus)

Opposing Functions of Microglial and Macrophagic TNFR2 in the Pathogenesis of Experimental Autoimmune Encephalomyelitis

Gao, H., Danzi, M. C., Choi, C. S., Taherian, M., Dalby-Hansen, C., Ellman, D. G., Madsen, P. M., Bixby, J., Lemmon, V., Lambertsen, K. L. & Brambilla, R., Jan 3 2017, In : Cell Reports. 18, 1, p. 198-212 15 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Tumor Necrosis Factor Receptors
Chemical activation
Monocytes
Macrophages
6 Citations (Scopus)

Pathogenic role and therapeutic potential of pleiotrophin in mouse models of ocular vascular disease

Wang, W., LeBlanc, M. E., Chen, X., Chen, P., Ji, Y., Brewer, M., Tian, H., Spring, S. R., Webster, K. A. & Li, W., Apr 26 2017, (Accepted/In press) In : Angiogenesis. p. 1-14 14 p.

Research output: Contribution to journalArticle

Eye Diseases
Vascular Diseases
Diabetic Retinopathy
Retinopathy of Prematurity
Macular Degeneration
49 Citations (Scopus)

Pharos: Collating protein information to shed light on the druggable genome

Nguyen, D. T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., Liu, G., Ma'ayan, A., Mandava, G., Mani, S., Mehta, S., Overington, J., Patel, J., Rouillard, A. D., Schuerer, S. C., Sheils, T. & 10 others, Simeonov, A., Sklar, L. A., Southall, N., Ursu, O., Vidovic, D., Waller, A., Yang, J., Jadhav, A., Oprea, T. I. & Guha, R., Jan 1 2017, In : Nucleic Acids Research. 45, D1, p. D995-D1002

Research output: Contribution to journalArticle

Knowledge Management
Genome
Databases
Proteins
Knowledge Bases
5 Citations (Scopus)
GTP-Binding Protein Regulators
Muscarinic M3 Receptors
Insulin
RGS Proteins
Cholinergic Agonists
13 Citations (Scopus)

Resealable, optically accessible, PDMS-free fluidic platform for ex vivo interrogation of pancreatic islets

Lenguito, G., Chaimov, D., Weitz, J. R., Rodriguez Diaz, R., Rawal, S. A. K., Tamayo-Garcia, A., Caicedo-Vierkant, D. A., Stabler, C. L., Buchwald, P. & Agarwal, A., 2017, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 17, 5, p. 772-781 10 p.

Research output: Contribution to journalArticle

Fluidics
Islets of Langerhans
Optogenetics
Perfusion
Insulin
34 Citations (Scopus)

Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting

Luo, J., Attard, G., Balk, S. P., Bevan, C., Burnstein, K. L., Cato, L., Cherkasov, A., De Bono, J. S., Dong, Y., Gao, A. C., Gleave, M., Heemers, H., Kanayama, M., Kittler, R., Lang, J. M., Lee, R. J., Logothetis, C. J., Matusik, R., Plymate, S., Sawyers, C. L. & 7 others, Selth, L. A., Soule, H., Tilley, W., Weigel, N. L., Zoubeidi, A., Dehm, S. M. & Raj, G. V., Jan 1 2017, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Castration
Therapeutics
Hematologic Tests
8 Citations (Scopus)

Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction

Chen, J., Song, Y., Bojadzic, D., Tamayo-Garcia, A., Landin, A. M., Blomberg, B. B. & Buchwald, P., Nov 9 2017, In : Journal of Medicinal Chemistry. 60, 21, p. 8906-8922 17 p.

Research output: Contribution to journalArticle

CD40 Ligand
Proteins
T-Lymphocytes
Isoantigens
Immunomodulation
15 Citations (Scopus)

Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome

Li, C., Brazill, J. M., Liu, S., Bello, C., Zhu, Y., Morimoto, M., Cascio, L., Pauly, R., Diaz-Perez, Z., Malicdan, M. C. V., Wang, H., Boccuto, L., Schwartz, C. E., Gahl, W. A., Boerkoel, C. F. & Zhai, R. G., Dec 1 2017, In : Nature Communications. 8, 1, 1257.

Research output: Contribution to journalArticle

Spermine Synthase
Oxidative stress
Polyamines
Oxidative Stress
causes
5 Citations (Scopus)

Stability and function of a putative microtubule-organizing center in the human parasite Toxoplasma gondii

Leung, J. M., He, Y., Zhang, F., Hwang, Y. C., Nagayasu, E., Liu, J., Murray, J. M. & Hu, K., May 15 2017, In : Molecular Biology of the Cell. 28, 10, p. 1361-1378 18 p.

Research output: Contribution to journalArticle

Microtubule-Organizing Center
Toxoplasma
Microtubules
Parasites
Toxoplasmosis
5 Citations (Scopus)

Stress increases peripheral axon growth and regeneration through glucocorticoid receptor-dependent transcriptional programs

Lerch, J. K., Alexander, J. K., Madalena, K. M., Motti, D., Quach, T., Dhamija, A., Zha, A., Gensel, J. C., Marketon, J. W., Lemmon, V., Bixby, J. & Popovich, P. G., Jul 1 2017, In : eNeuro. 4, 4, e0246-17.2017.

Research output: Contribution to journalArticle

Glucocorticoid Receptors
Axons
Regeneration
Spinal Ganglia
Sensory Receptor Cells
12 Citations (Scopus)

Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia

Reiter, J., Drummond, S., Sammour, I., Huang, J., Florea, V., Dornas, P., Hare, J., Rodrigues, C. D. & Young, K., Jul 12 2017, In : Respiratory Research. 18, 1, 137.

Research output: Contribution to journalArticle

Bronchopulmonary Dysplasia
Mesenchymal Stromal Cells
Rodentia
Lung
Hyperoxia
1 Citation (Scopus)

Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

Ondachi, P. W., Castro, A. H., Sherman, B., Luetje, C. W., Damaj, M. I., Mascarella, S. W., Navarro, H. A. & Carroll, F. I., Jan 18 2017, In : ACS Chemical Neuroscience. 8, 1, p. 115-127 13 p.

Research output: Contribution to journalArticle

Hypothermia
epibatidine
Nicotinic Receptors
Nicotine
Assays
12 Citations (Scopus)

Systemic QSAR and phenotypic virtual screening: Chasing butterflies in drug discovery

Cruz-Monteagudo, M., Schuerer, S. C., Tejera, E., Pérez-Castillo, Y., Medina-Franco, J. L., Sánchez-Rodríguez, A. & Borges, F., 2017, (Accepted/In press) In : Drug Discovery Today.

Research output: Contribution to journalArticle

Butterflies
Quantitative Structure-Activity Relationship
Drug Discovery
Systems Biology
Neuroprotective Agents
7 Citations (Scopus)

Targeting AR variant–coactivator interactions to exploit prostate cancer vulnerabilities

Magani, F., Peacock, S. O., Rice, M. A., Martinez, M. J., Greene, A. M., Magani, P. S., Lyles, R., Weitz, J. R. & Burnstein, K. L., Nov 1 2017, In : Molecular Cancer Research. 15, 11, p. 1469-1480 12 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Androgen Receptors
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
6 Citations (Scopus)

Teaching an old drug new tricks: Agonism, antagonism, and biased signaling of pilocarpine through M3 muscarinic acetylcholine receptor

Pronin, A. N., Wang, Q. & Slepak, V. Z., Nov 1 2017, In : Molecular Pharmacology. 92, 5, p. 601-612 12 p.

Research output: Contribution to journalArticle

Pilocarpine
Muscarinic Receptors
Teaching
Carbachol
Pharmaceutical Preparations
25 Citations (Scopus)

The mTOR substrate S6 kinase 1 (S6K1) is a negative regulator of axon regeneration and a potential drug target for central nervous system injury

Al-Ali, H., Ding, Y., Slepak, T., Wu, W., Sun, Y., Martinez, Y., Xu, X. M., Lemmon, V. & Bixby, J., Jul 26 2017, In : Journal of Neuroscience. 37, 30, p. 7079-7095 17 p.

Research output: Contribution to journalArticle

Ribosomal Protein S6 Kinases
Nervous System Trauma
Axons
Regeneration
Pharmaceutical Preparations
8 Citations (Scopus)

Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer

Samaranayake, G. J., Troccoli, C. I., Huynh, M., Lyles, R. D. Z., Kage, K., Win, A., Lakshmanan, V., Kwon, D., Ban, Y., Chen, X., Zarco, E. R., Jorda, M., Burnstein, K. L. & Rai, P., Dec 1 2017, In : Nature Communications. 8, 1, 1204.

Research output: Contribution to journalArticle

Thioredoxins
vulnerability
Castration
Androgen Receptors
Oxidation-Reduction
5 Citations (Scopus)

TIN-X: target importance and novelty explorer

Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., Schuerer, S. C., Jensen, L. J., Sklar, L. A., Bologa, C. G. & Oprea, T. I., Aug 15 2017, In : Bioinformatics (Oxford, England). 33, 16, p. 2601-2603 3 p.

Research output: Contribution to journalArticle

Proteins
Protein
Receptor
Target
G-Protein-Coupled Receptor Kinases
2016
10 Citations (Scopus)

Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging

Ruetenik, A. L., Ocampo, A., Ruan, K., Zhu, Y., Li, C., Zhai, R. G. & Barrientos, A., Aug 1 2016, In : Microbial Cell. 3, 8, p. 338-351 14 p.

Research output: Contribution to journalArticle

Open Access
Oxidative Phosphorylation
Diptera
Yeast
Toxicity
Aging of materials
6 Citations (Scopus)

Auxilin facilitates membrane traffic in the early secretory pathway

Ding, J., Segarra, V. A., Chen, S., Cai, H., Lemmon, S. & Ferro-Novick, S., Jan 1 2016, In : Molecular Biology of the Cell. 27, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Auxilins
Coat Protein Complex I
Secretory Pathway
Membranes
Clathrin-Coated Vesicles

Building concordant ontologies for drug discovery

Küçük-McGinty, H., Mehta, S., Lin, Y., Nabizadeh, N., Stathias, V., Vidovic, D., Koleti, A., Mader, C., Duan, J., Visser, U. E. & Schuerer, S. C., 2016, In : CEUR Workshop Proceedings. 1747

Research output: Contribution to journalArticle

Ontology
Bioassay
Drug Discovery
Genes
5 Citations (Scopus)

Cell length growth patterns in fission yeast reveal a novel size control mechanism operating in late G2 phase

Horváth, A., Rácz-Mónus, A., Buchwald, P. & Sveiczer, Á., Sep 1 2016, In : Biology of the Cell. 108, 9, p. 259-277 19 p.

Research output: Contribution to journalArticle

Schizosaccharomyces
G2 Phase
Growth
Cell Size
Saccharomycetales
2 Citations (Scopus)

Creating a chimeric clathrin heavy chain that functions independently of yeast clathrin light chain

Boettner, D. R., Segarra, V. A., Moorthy, B. T., de León, N., Creagh, J., Collette, J. R., Malhotra, A. & Lemmon, S., Jul 1 2016, In : Traffic. 17, 7, p. 754-768 15 p.

Research output: Contribution to journalArticle

Clathrin Light Chains
Clathrin Heavy Chains
Clathrin
Yeast
trans-Golgi Network
5 Citations (Scopus)

Dose-escalation study of octanoic acid in patients with essential tremor

Voller, B., Lines, E., McCrossin, G., Tinaz, S., Lungu, C., Grimes, G., Starling, J., Potti, G., Buchwald, P., Haubenberger, D. & Hallett, M., Apr 1 2016, In : Journal of Clinical Investigation. 126, 4, p. 1451-1457 7 p.

Research output: Contribution to journalArticle

Essential Tremor
Tremor
Maximum Tolerated Dose
Pharmacokinetics
1-Octanol
5 Citations (Scopus)

Edelfosine promotes apoptosis in androgen-deprived prostate tumors by increasing atf3 and inhibiting androgen receptor activity

Udayakumar, T., Stoyanova, R., Shareef, M. M., Mu, Z., Philip, S., Burnstein, K. L. & Pollack, A., Jun 1 2016, In : Molecular Cancer Therapeutics. 15, 6, p. 1353-1363 11 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Prostate
Activating Transcription Factor 3
Apoptosis