Molecular and Cellular Pharmacology

Research Output

Filter
Article

Hypoxia regulates β-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element

Discher, D. J., Bishopric, N. H., Wu, X., Peterson, C. A. & Webster, K. A., Oct 2 1998, In : Journal of Biological Chemistry. 273, 40, p. 26087-26093 7 p.

Research output: Contribution to journalArticle

142 Scopus citations

Hypoxic Stress Decreases c-Myc Protein Stability in Cardiac Progenitor Cells Inducing Quiescence and Compromising Their Proliferative and Vasculogenic Potential

Bellio, M. A., Pinto, M. T., Florea, V., Barrios, P. A., Taylor, C. N., Brown, A. B., Lamondin, C., Hare, J., Schulman, I. H. & Rodrigues, C. D., Dec 1 2017, In : Scientific Reports. 7, 1, 9702.

Research output: Contribution to journalArticle

4 Scopus citations

Identification and cloning of two putative subunits of DNA polymerase epsilon in fussion yeast

Spiga, M. G. & D'Urso, G., Nov 9 2004, In : Nucleic acids research. 32, 16, p. 4945-4953 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification of an alternatively spliced avian member of the synaptophysin gene family

Bixby, J. L., May 1992, In : Molecular Brain Research. 13, 4, p. 339-348 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Identification of an oncogenic network with prognostic and therapeutic value in prostate cancer

Magani, F., Bray, E. R., Martinez, M. J., Zhao, N., Copello, V. A., Heidman, L., Peacock, S. O., Wiley, D. J., D'Urso, G. & Burnstein, K. L., Aug 2018, In : Molecular Systems Biology. 14, 8, e8202.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

Allen, B. K., Mehta, S., Ember, S. W. J., Zhu, J. Y., Schönbrunn, E., Ayad, N. & Schuerer, S. C., Jan 1 2017, In : ACS Omega. 2, 8, p. 4760-4771 12 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Identification of a truncated form of methionine sulfoxide reductase a expressed in mouse embryonic stem cells

Jia, P., Zhang, C., Jia, Y., Webster, K. A., Huang, X., Kochegarov, A. A., Lemanski, S. L. & Lemanski, L. F., Jun 24 2011, In : Journal of Biomedical Science. 18, 1, 46.

Research output: Contribution to journalArticle

1 Scopus citations

Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library

Gibbons, G. S., Chakraborty, A., Grigsby, S. M., Umeano, A. C., Liao, C., Moukha-Chafiq, O., Pathak, V., Mathew, B., Lee, Y. T., Dou, Y., Schürer, S. C., Reynolds, R. C., Snowden, T. S. & Nikolovska-Coleska, Z., Mar 1 2020, In : European Journal of Medicinal Chemistry. 189, 112023.

Research output: Contribution to journalArticle

Identification of new agonists and antagonists of the insect odorant receptor co-receptor subunit

Chen, S. & Luetje, C. W., May 8 2012, In : PloS one. 7, 5, e36784.

Research output: Contribution to journalArticle

42 Scopus citations

Identification of novel agonists of the integrin CD11b/CD18

Faridi, M. H., Maiguel, D., Barth, C. J., Stoub, D., Day, R., Schürer, S. & Gupta, V., Dec 15 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 24, p. 6902-6906 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors

Everhart, D., Reiller, E., Mirzoian, A., McIntosh, J. M., Malhotra, A. & Luetje, C. W., Aug 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 306, 2, p. 664-670 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening

Bialkowska, A. B., Crisp, M., Bannister, T., He, Y., Chowdhury, S., Schur̈er, S., Chase, P., Spicer, T., Madoux, F., Tian, C., Hodder, P., Zaharevitz, D. & Yang, V. W., Nov 1 2011, In : Molecular cancer therapeutics. 10, 11, p. 2043-2051 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Identification of suppressor of Clathrin deficiency-1 (SCD1) and its connection to Clathrin-mediated endocytosis in Saccharomyces cerevisiae

Moorthy, B. T., Sharma, A., Boettner, D. R., Wilson, T. E. & Lemmon, S. K., Mar 1 2019, In : G3: Genes, Genomes, Genetics. 9, 3, p. 867-877 11 p.

Research output: Contribution to journalArticle

Open Access

Identification of the Gβ5-RGS7 protein complex in the retina

Cabrera, J. L., De Freitas, F., Satpaev, D. K. & Slepak, V. Z., Aug 28 1998, In : Biochemical and biophysical research communications. 249, 3, p. 898-902 5 p.

Research output: Contribution to journalArticle

107 Scopus citations

Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro

Bixby, J. L., Lilien, J. & Reichardt, L. F., 1988, In : Journal of Cell Biology. 107, 1, p. 353-361 9 p.

Research output: Contribution to journalArticle

Open Access
356 Scopus citations

III. Hormonal regulation of phosphatidylinositol breakdown

Fain, J. N., Lin, S. H., Litosch, I. & Wallace, M., May 2 1983, In : Life Sciences. 32, 18, p. 2055-2067 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Impact of familial hypertrophic cardiomyopathy-linked mutations in the NH2 terminus of the RLC on β-myosin cross-bridge mechanics

Farman, G. P., Muthu, P., Kazmierczak, K., Szczesna-Cordary, D. & Moore, J. R., Dec 15 2014, In : Journal of applied physiology (Bethesda, Md. : 1985). 117, 12, p. 1471-1477 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Impaired CXCR4 expression and cell engraftment of bone marrow-derived cells from aged atherogenic mice

Xu, Q., Wang, JA., He, J., Zhou, M., Adi, J., Webster, K. A. & Yu, H., Nov 1 2011, In : Atherosclerosis. 219, 1, p. 92-99 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
Open Access
3 Scopus citations

Incidence of heart failure in infarcted rats that die spontaneously

Flumignan, R. L. G., Kanashiro, R. M., Saraiva, R. M., Portes, L. A., Antonio, E. L., Ishigai, M. M. S. & Tucci, P. J. F., Oct 2006, In : Brazilian Journal of Medical and Biological Research. 39, 10, p. 1323-1328 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Increased expression of cyclin B1 sensitizes prostate cancer cells to apoptosis induced by chemotherapy

Gomez, L. A., De Las Pozas, A., Reiner, T., Burnstein, K. & Perez-Stable, C., May 1 2007, In : Molecular cancer therapeutics. 6, 5, p. 1534-1543 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Induction and nuclear accumulation of Fos and Jun proto-oncogenes in hypoxic cardiac myocytes

Webster, K. A., Discher, D. J. & Bishopric, N. H., Jan 1 1993, In : Journal of Biological Chemistry. 268, 22, p. 16852-16858 7 p.

Research output: Contribution to journalArticle

190 Scopus citations

Inflammasome activation induces pyroptosis in the retina exposed to ocular hypertension injury

Pronin, A., Pham, D., An, W., Dvoriantchikova, G., Reshetnikova, G., Qiao, J., Kozhekbaeva, Z., Reiser, A. E., Slepak, V. Z. & Shestopalov, V. I., Feb 12 2019, In : Frontiers in Molecular Neuroscience. 12, 36.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Influence of diet on visceral adipose remodeling in NONcNZO10 mice with polygenic susceptibility for type 2 diabetes

Adi, N. C., Adi, J. N., Cesar, L., Agatston, A. S., Kurlansky, P. & Webster, K. A., Oct 1 2012, In : Obesity. 20, 10, p. 2142-2146 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Influence of the N-acetylation polymorphism on the metabolism of talampanel: An investigation in fasted and fed subjects genotyped for NAT2 variants

Buchwald, P., Juhász, A., Bell, C., Pátfalusi, M., Kovács, P., Hochhaus, G., Howes, J. & Bodor, N., Feb 1 2006, In : Pharmazie. 61, 2, p. 125-134 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Inhibition of androgen receptor transcriptional activity as a novel mechanism of action of arsenic

Rosenblatt, A. E. & Burnstein, K. L., Mar 1 2009, In : Molecular Endocrinology. 23, 3, p. 412-421 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit

Kepchia, D., Moliver, S., Chohan, K., Phillips, C. & Luetje, C. W., May 1 2017, In : PLoS One. 12, 5, e0177454.

Research output: Contribution to journalArticle

4 Scopus citations

Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids

Vang, T., Xie, Y., Liu, W. H., Vidović, D., Liu, Y., Wu, S., Smith, D. H., Rinderspacher, A., Chung, C., Gong, G., Mustelin, T., Landry, D. W., Rickert, R. C., Schürer, S. C., Deng, S. X. & Tautz, L., Jan 27 2011, In : Journal of Medicinal Chemistry. 54, 2, p. 562-571 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Inhibition of p53 function prevents renin-angiotensin system activation and stretch-mediated myocyte apoptosis

Leri, A., Fiordaliso, F., Setoguchi, M., Limana, F., Bishopric, N. H., Kajstura, J., Webster, K. & Anversa, P., Jan 1 2000, In : American Journal of Pathology. 157, 3, p. 843-857 15 p.

Research output: Contribution to journalArticle

62 Scopus citations

Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer

Rosenblatt, A. E., Garcia, M. I., Lyons, L., Xie, Y., Maiorino, C., Désiré, L., Slingerland, J. & Burnstein, K. L., Apr 2011, In : Endocrine-related cancer. 18, 2, p. 207-219 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Inhibition of the vacuolar ATPase induces Bnip3-dependent death of cancer cells and a reduction in tumor burden and metastasis

Graham, R. M., Thompson, J. W. & Webster, K. A., 2014, In : Oncotarget. 5, 5, p. 1162-1173 12 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Inhibition of tyrosine phosphorylation potentiates substrate‐induced neurite growth

Bixby, J. L. & Jhabvala, P., Jul 1992, In : Journal of Neurobiology. 23, 5, p. 468-480 13 p.

Research output: Contribution to journalArticle

76 Scopus citations

Inhibitory regulation of phospholipase C-β1 by a G protein dependent mechanism

Litosch, I., Dec 1 1996, In : FASEB Journal. 10, 6, p. A1253

Research output: Contribution to journalArticle

Inotropic Stimulation Induces Cardiac Dysfunction in Transgenic Mice Expressing a Troponin T (I79N) Mutation Linked to Familial Hypertrophic Cardiomyopathy

Knollmann, B. C., Blatt, S. A., Horton, K., De Freitas, F., Miller, T., Bell, M., Housmans, P. R., Weissman, N. J., Morad, M. & Potter, J. D., Mar 30 2001, In : Journal of Biological Chemistry. 276, 13, p. 10039-10048 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing

Kumar, A., Birnbaum, M. D., Moorthy, B. T., Singh, J., Palovcak, A., Patel, D. M. & Zhang, F., Jul 24 2019, In : BMC genomics. 20, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Instability of a multiple copy enhancer in plasmid vectors: Practical considerations

Discher, D. J., Bishopric, N. H., Hernandez, O. M. & Webster, K. A., 1999, In : BioTechniques. 26, 6, p. 1026-1030 5 p.

Research output: Contribution to journalArticle

Open Access

Institutional open access funds: Now is the time

Eckman, C. D. & Weil, B. T., May 2010, In : PLoS biology. 8, 5

Research output: Contribution to journalArticle

12 Scopus citations

Insulin resistance of denervated rat muscle: A model for impaired receptor-function coupling

Burant, C. F., Lemmon, S. K., Treutelaar, M. K. & Buse, M. G., 1984, In : American Journal of Physiology - Endocrinology and Metabolism. 10, 5, p. E657-E666

Research output: Contribution to journalArticle

74 Scopus citations
13 Scopus citations

Interaction of Calmodulin with Skeletal Muscle Myosin Light Chain Kinase

Crouch, T. H., Holroyde, M. J., Collins, J. H., Solaro, R. J. & Potter, J. D., Oct 1981, In : Biochemistry. 20, 22, p. 6318-6325 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
15 Scopus citations

Interaction of retinal guanylate cyclase with the α subunit of transducin: Potential role in transducin localization

Rosenweig, D. H., Nair, S. K., Levay, K., Peshenko, I., Crabb, J. W., Dizhoor, A. M. & Slepak, V. Z., Feb 1 2009, In : Biochemical Journal. 417, 3, p. 803-812 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Interaction of rhodopsin kinase with recoverin and calmodulin

Satpaev, D. K., Levay, K. & Zslepak, V., Dec 1 1998, In : FASEB Journal. 12, 8, p. A1438

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
87 Scopus citations

Intramolecular interaction between the DEP domain of RGS7 and the Gβ5 subunit

Narayanan, V., Sandiford, S. L., Wang, Q., Keren-Raifman, T., Levay, K. & Slepak, V. Z., Jun 12 2007, In : Biochemistry. 46, 23, p. 6859-6870 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Investigating the role of Ca2+-binding site IV in barnacle troponin C

Allhouse, L. D., Li, Q., Guzman, G., Miller, T., Lipscomb, S., Potter, J. D. & Ashley, C. C., Jan 1 2000, In : Pflugers Archiv European Journal of Physiology. 439, 5, p. 600-609 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Investigation of a genetically engineered mutant of barnacle troponin C containing a central helix deletion

Allhouse, L. D., Miller, T., Li, Q., Guzman, G., Potter, J. D., Mandveno, A. & Ashley, C. C., Jan 1 1999, In : Pflugers Archiv European Journal of Physiology. 439, 1-2, p. 67-75 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Invited review: Pathophysiology of cardiac muscle contraction and relaxation as a result of alterations in thin filament regulation

Hernandez, O. M., Housmans, P. R. & Potter, J. D., Jan 1 2001, In : Journal of applied physiology. 90, 3, p. 1125-1136 12 p.

Research output: Contribution to journalArticle

57 Scopus citations