Molecular and Cellular Pharmacology

Research Output

Filter
Article

Functional Effects of a Restrictive-Cardiomyopathy-Linked Cardiac Troponin I Mutation (R145W) in Transgenic Mice

Wen, Y., Xu, Y., Wang, Y., Pinto, J. R., Potter, J. D. & Kerrick, W. G. L., Oct 9 2009, In : Journal of molecular biology. 392, 5, p. 1158-1167 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Fusigenic liposome-mediated DNA transfer into cardiac myocytes

Ellison, K. E., Bishopric, N. H., Webster, K. A., Morishita, R., Gibbons, G. H., Kaneda, Y., Sato, B. & Dzau, V. J., Jul 1996, In : Journal of Molecular and Cellular Cardiology. 28, 7, p. 1385-1399 15 p.

Research output: Contribution to journalArticle

28 Scopus citations

G39, GTP-binding protein from bovine cerebellum. Amino acid sequence and nucleotide sequence of the corresponding cDNA

Ovchinnikov, Y. A., Slepak, V. Z., Pronin, A. N., Shlenskii, A. B., Levina, N. B., Voeikov, V. L., Bystrov, N. S., Severtsova, I. V. & Lipkin, V. M., Jan 1 1987, In : Doklady Biochemistry. 297, 1-6, p. 404-406 3 p.

Research output: Contribution to journalArticle

G39--GTP-sviazyvaiushchiǐ belok iz mozzhechka byka. Aminokislotnaia posledovatel'nost' i nukleotidnaia posledovatel'nost' sootvetstvuiushcheǐ kDNK.

Translated title of the contribution: G39, a GTP-binding protein from the bovine cerebellum. Amino acid sequence and nucleotide sequence of corresponding cDNAOvchinnikov, I. A., Slepak, V. Z., Pronin, A. N., Shlenskiǐ, A. B. & Levina, N. B., Dec 1 1987, In : Doklady Akademii nauk SSSR. 297, 4, p. 1006-1009 4 p.

Research output: Contribution to journalArticle

GABAA receptor subunit mRNA expression in cultured embryonic and adult human dorsal root ganglion neurons

Maddox, F. N., Valeyev, A. Y., Poth, K., Holohean, A. M., Wood, P. M., Davidoff, R. A., Hackman, J. C. & Luetje, C. W., Apr 19 2004, In : Developmental Brain Research. 149, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

GADD45γ: A new vitamin D-regulated gene that is antiproliferative in prostate cancer cells

Flores, O. & Burnstein, K. L., Oct 1 2010, In : Endocrinology. 151, 10, p. 4654-4664 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain

Huang, W., Kazmierczak, K., Zhou, Z., Aguiar-Pulido, V., Narasimhan, G. & Szczesna-Cordary, D., Nov 1 2015, (Accepted/In press) In : Archives of Biochemistry and Biophysics.

Research output: Contribution to journalArticle

5 Scopus citations

General linearized biexponential model for QSAR data showing bilinear-type distribution

Buchwald, P., Nov 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2355-2379 25 p.

Research output: Contribution to journalArticle

27 Scopus citations

Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy

Wang, Y., Pinto, J. R., Solis, R. S., Dweck, D., Liang, J., Diaz-Perez, Z., Ge, Y., Walker, J. W. & Potter, J. D., Jan 13 2012, In : Journal of Biological Chemistry. 287, 3, p. 2156-2167 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury

Dvoriantchikova, G., Ivanov, D., Barakat, D., Grinberg, A., Wen, R., Slepak, V. Z. & Shestopalov, V. I., Feb 23 2012, In : PloS one. 7, 2, e31991.

Research output: Contribution to journalArticle

70 Scopus citations

Genetic dissection of sperm individualization in Drosophila melanogaster

Fabrizio, J. J., Hime, G., Lemmon, S. K. & Bazinet, C., Jun 26 1998, In : Development. 125, 10, p. 1833-1843 11 p.

Research output: Contribution to journalArticle

138 Scopus citations

Genetic elucidation of human hyperosmia to isovaleric acid

Menashe, I., Abaffy, T., Hasin, Y., Goshen, S., Yahalom, V., Luetje, C. W. & Lancet, D., Nov 1 2007, In : PLoS biology. 5, 11, p. 2462-2468 7 p.

Research output: Contribution to journalArticle

131 Scopus citations

Genetic instability of clathrin-deficient strains of Saccharomyces cerevisiae

Lemmon, S. K., Freund, C., Conley, K. & Jones, E. W., Jan 19 1990, In : Genetics. 124, 1, p. 27-38 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites

Parrish, J. Z., Kim, M. D., Lily, Y. J. & Yuh, N. J., Apr 1 2006, In : Genes and Development. 20, 7, p. 820-835 16 p.

Research output: Contribution to journalArticle

148 Scopus citations

Germinal center-specific protein human germinal center associated lymphoma directly interacts with both myosin and actin and increases the binding of myosin to actin

Lu, X., Kazmierczak, K., Jiang, X., Jones, M., Watt, J., Helfman, D. M., Moore, J. R., Szczesna-Cordary, D. & Lossos, I. S., Jun 1 2011, In : FEBS Journal. 278, 11, p. 1922-1931 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Getting in Touch with the Clathrin Terminal Domain

Lemmon, S. K. & Traub, L. M., Apr 1 2012, In : Traffic. 13, 4, p. 511-519 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Global Deletion of Trp53 Reverts Ovarian Tumor Phenotype of the Germ Cell–Deficient White Spotting Variant (Wv) Mice

Cai, K. Q., Wang, Y., Smith, E. R., Smedberg, J. L., Yang, D. H., Yang, W. L. & Xu, X., Jan 1 2015, In : Neoplasia. 17, 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors

Cornacchia, F., Fornoni, A., Plati, A. R., Thomas, A., Wang, Y., Inverardi, L., Striker, L. J. & Striker, G. E., Dec 29 2001, In : Journal of Clinical Investigation. 108, 11, p. 1649-1656 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

Buchwald, P., Feb 1 2008, In : Steroids. 73, 2, p. 193-208 16 p.

Research output: Contribution to journalArticle

31 Scopus citations

Glucose-stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets

Buchwald, P., Tamayo-Garcia, A., Manzoli, V., Tomei, A. & Stabler, C. L., 2017, (Accepted/In press) In : Biotechnology and Bioengineering.

Research output: Contribution to journalArticle

17 Scopus citations

Glycosaminoglycan-dependent and -independent inhibition of neurite outgrowth by agrin

Baerwald-De La Torre, K., Winzen, U., Halfter, W. & Bixby, J. L., Jul 1 2004, In : Journal of neurochemistry. 90, 1, p. 50-61 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Glycosylation within the Cystein loop and six residues near conserved Cys192/Cys193 are determinants of neuronal bungarotoxin sensitivity on the neuronal nicotinic receptor α3 subunit

Luetje, C. W., Maddox, F. N. & Harvey, S. C., Jun 1 1998, In : Molecular Pharmacology. 53, 6, p. 1112-1119 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1

Chan, Y. M., Broder-Fingert, S., Paraschos, S., Lapatto, R., Au, M., Hughes, V., Bianco, S. D. C., Min, L., Plummer, L., Cerrato, F., De Guillebon, A., Wu, I. H., Wahab, F., Dwyer, A., Kirsch, S., Quinton, R., Cheetham, T., Ozata, M., Ten, S., Chanoine, J. P. & 8 others, Pitteloud, N., Martin, K. A., Schiffmann, R., Van Der Kamp, H. J., Nader, S., Hall, J. E., Kaiser, U. B. & Seminara, S. B., Nov 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 11, p. E1771-E1781

Research output: Contribution to journalArticle

41 Scopus citations

Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle

Percival, J. M., Anderson, K. N. E., Huang, P., Adams, M. E. & Froehner, S. C., Mar 1 2010, In : Journal of Clinical Investigation. 120, 3, p. 816-826 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

GPCR ontology: Development and application of a G protein-coupled receptor pharmacology knowledge framework

Przydzial, M. J., Bhhatarai, B., Koleti, A., Vempati, U., Schürer, S. C. & Wren, J., Dec 15 2013, In : Bioinformatics. 29, 24, p. 3211-3219 9 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

G-protein inhibition of phospholipase C-β1 in membranes: Role of G-protein βγ subunits

Litosch, I., Jan 1 1996, In : Biochemical Journal. 319, 1, p. 173-178 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

G protein-mediated inhibition of phospholipase C activity in a solubilized membrane preparation

Litosch, I., Sulkholutskaya, I. & Weng, C., Jan 1 1993, In : Journal of Biological Chemistry. 268, 12, p. 8692-8697 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
21 Scopus citations

G-protein βγ subunits antagonize protein kinase C-dependent phosphorylation and inhibition of phospholipase C-β1

Litosch, I., Sep 15 1997, In : Biochemical Journal. 326, 3, p. 701-707 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Growth cone steering by receptor tyrosine phosphatase δ defines a distinct class of guidance cue

Sun, Q. L., Wang, J., Bookman, R. J. & Bixby, J. L., Jan 1 2000, In : Molecular and Cellular Neuroscience. 16, 5, p. 686-695 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine With subacute ischemic cardiomyopathy

Bagno, L. L., Takeuchi, R., Suncion, V. Y., Golpanian, S., Karantalis, V., Wolf, A., Wang, B., Premer, C., Balkan, W. E., Rodriguez, J., Valdes, D., Rosado, M., Block, N. L., Goldstein, P., Morales, A. R., Cai, R. Z., Sha, W., Schally, A. V. & Hare, J., 2015, In : Journal of the American Heart Association. 4, 4, e001464.

Research output: Contribution to journalArticle

12 Scopus citations

GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation

Penas, C., Mishra, J. K., Wood, S. D., Schuerer, S. C., Roush, W. R. & Ayad, N., Feb 1 2015, In : Cell Cycle. 14, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

GSK3 involvement in amylin signaling in isolated rat soleus muscle

Abaffy, T. & Cooper, G. J. S., Dec 1 2004, In : Peptides. 25, 12, p. 2119-2125 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
10 Scopus citations

Guanine nucleotide and NaF stimulation of phospholipase C activity in rat cerebral-cortical membranes. Studies on substrate specificity

Litosch, I., Jan 1 1987, In : Biochemical Journal. 244, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Guanine nucleotides mediate stimulatory and inhibitory effects on cerebral-cortical membrane phospholipase C activity

Litosch, I., Jan 1 1989, In : Biochemical Journal. 261, 1, p. 245-251 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Gα16, a G protein α subunit specifically expressed in hematopoietic cells

Amatruda, T. T., Steele, D. A., Slepak, V. Z. & Simon, M. I., Sep 4 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 13, p. 5587-5591 5 p.

Research output: Contribution to journalArticle

Open Access
226 Scopus citations
82 Scopus citations

Gβ5-RGS7 inhibits Gαq-mediated signaling via a direct protein-protein interaction

Witherow, D. S., Tovey, S. C., Wang, Q., Willars, G. B. & Slepak, V. Z., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 21307-21313 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex

Karpinsky-Semper, D., Tayou, J., Levay, K., Schuchardt, B. J., Bhat, V., Volmar, C. H., Farooq, A. & Slepak, V. Z., Feb 3 2015, In : Biochemistry. 54, 4, p. 1077-1088 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis

Hu, X., Zhang, L., Jin, J., Zhu, W., Xu, Y., Wu, Y., Wang, Y., Chen, H., Webster, K. A., Chen, H., Yu, H. & Wang, J., Jun 1 2015, In : Stem Cells. 33, 6, p. 1850-1862 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Hepatocyte growth factor and vitamin D cooperatively inhibit androgen-unresponsive prostate cancer cell lines

Qadan, L. R., Perez-Stable, C. M., Schwall, R. H., Burnstein, K. L., Ostenson, R. C., Howard, G. A. & Roos, B. A., Jan 1 2000, In : Endocrinology. 141, 7, p. 2567-2573 7 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Hepatoma-derived growth factor-related protein-3 is a novel angiogenic factor

LeBlanc, M. E., Wang, W., Caberoy, N. B., Chen, X., Guo, F., Alvarado, G., Shen, C., Wang, F., Wang, H., Chen, R., Liu, Z-J., Webster, K. A. & Li, W., May 21 2015, In : PLoS One. 10, 5, e0127904.

Research output: Contribution to journalArticle

10 Scopus citations

Heterogeneity in SDF-1 expression defines the vasculogenic potential of adult cardiac progenitor cells

Rodrigues, C. O., Shehadeh, L. A., Hoosien, M., Otero, V., Chopra, I., Tsinoremas, N. F. & Bishopric, N. H., Aug 24 2011, In : PloS one. 6, 8, e24013.

Research output: Contribution to journalArticle

11 Scopus citations

Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia

Poth, K., Nutter, T. J., Cuevas, J., Parker, M. J., Adams, D. J. & Luetje, C. W., Jan 20 1997, In : Journal of Neuroscience. 17, 2, p. 586-596 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

High-content analysis of proapoptotic EphA4 dependence receptor functions using small-molecule libraries

Nelersa, C. M., Barreras, H., Runko, E., Ricard, J., Shi, Y., Glass, S. J., Bixby, J. L., Lemmon, V. P. & Liebl, D. J., Jul 1 2012, In : Journal of Biomolecular Screening. 17, 6, p. 785-795 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

High content screening of cortical neurons identifies novel regulators of axon growth

Blackmore, M. G., Moore, D. L., Smith, R. P., Goldberg, J. L., Bixby, J. L. & Lemmon, V. P., May 1 2010, In : Molecular and Cellular Neuroscience. 44, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

74 Scopus citations

High quality, small molecule-activity datasets for kinase research [version 1; referees: 2 approved]

Sharma, R., Schuerer, S. C. & Muskal, S. M., 2016, In : F1000Research. 5, 1366.

Research output: Contribution to journalArticle

5 Scopus citations

High quality, small molecule-activity datasets for kinase research [version 2; referees: 2 approved]

Sharma, R., Schuerer, S. C. & Muskal, S. M., 2016, In : F1000Research. 5, 1366.

Research output: Contribution to journalArticle

1 Scopus citations

High-throughput screening based identification of small molecule antagonists of integrin CD11b/CD18 ligand binding

Faridi, M. H., Maiguel, D., Brown, B. T., Suyama, E., Barth, C. J., Hedrick, M., Vasile, S., Sergienko, E., Schürer, S. & Gupta, V., Mar 26 2010, In : Biochemical and biophysical research communications. 394, 1, p. 194-199 6 p.

Research output: Contribution to journalArticle

3 Scopus citations