Molecular and Cellular Pharmacology

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General linearized biexponential model for QSAR data showing bilinear-type distribution

Buchwald, P., Nov 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2355-2379 25 p.

Research output: Contribution to journalArticle

27 Scopus citations

Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy

Wang, Y., Pinto, J. R., Solis, R. S., Dweck, D., Liang, J., Diaz-Perez, Z., Ge, Y., Walker, J. W. & Potter, J. D., Jan 13 2012, In : Journal of Biological Chemistry. 287, 3, p. 2156-2167 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury

Dvoriantchikova, G., Ivanov, D., Barakat, D., Grinberg, A., Wen, R., Slepak, V. Z. & Shestopalov, V. I., Feb 23 2012, In : PloS one. 7, 2, e31991.

Research output: Contribution to journalArticle

73 Scopus citations

Genetic elucidation of human hyperosmia to isovaleric acid

Menashe, I., Abaffy, T., Hasin, Y., Goshen, S., Yahalom, V., Luetje, C. W. & Lancet, D., Nov 2007, In : PLoS biology. 5, 11, p. 2462-2468 7 p.

Research output: Contribution to journalArticle

133 Scopus citations

Germinal center-specific protein human germinal center associated lymphoma directly interacts with both myosin and actin and increases the binding of myosin to actin

Lu, X., Kazmierczak, K., Jiang, X., Jones, M., Watt, J., Helfman, D. M., Moore, J. R., Szczesna-Cordary, D. & Lossos, I. S., Jun 1 2011, In : FEBS Journal. 278, 11, p. 1922-1931 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Getting in Touch with the Clathrin Terminal Domain

Lemmon, S. K. & Traub, L. M., Apr 1 2012, In : Traffic. 13, 4, p. 511-519 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Global Deletion of Trp53 Reverts Ovarian Tumor Phenotype of the Germ Cell–Deficient White Spotting Variant (Wv) Mice

Cai, K. Q., Wang, Y., Smith, E. R., Smedberg, J. L., Yang, D. H., Yang, W. L. & Xu, X. X., Jan 1 2015, In : Neoplasia. 17, 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors

Cornacchia, F., Fornoni, A., Plati, A. R., Thomas, A., Wang, Y., Inverardi, L., Striker, L. J. & Striker, G. E., Dec 29 2001, In : Journal of Clinical Investigation. 108, 11, p. 1649-1656 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

Buchwald, P., Feb 1 2008, In : Steroids. 73, 2, p. 193-208 16 p.

Research output: Contribution to journalArticle

31 Scopus citations

Glucose-stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets

Buchwald, P., Tamayo-Garcia, A., Manzoli, V., Tomei, A. A. & Stabler, C., 2017, (Accepted/In press) In : Biotechnology and Bioengineering.

Research output: Contribution to journalArticle

21 Scopus citations

Glycosaminoglycan-dependent and -independent inhibition of neurite outgrowth by agrin

Baerwald-De La Torre, K., Winzen, U., Halfter, W. & Bixby, J. L., Jul 1 2004, In : Journal of neurochemistry. 90, 1, p. 50-61 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Glycosylation within the Cystein loop and six residues near conserved Cys192/Cys193 are determinants of neuronal bungarotoxin sensitivity on the neuronal nicotinic receptor α3 subunit

Luetje, C. W., Maddox, F. N. & Harvey, S. C., Jun 1 1998, In : Molecular Pharmacology. 53, 6, p. 1112-1119 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1

Chan, Y. M., Broder-Fingert, S., Paraschos, S., Lapatto, R., Au, M., Hughes, V., Bianco, S. D. C., Min, L., Plummer, L., Cerrato, F., De Guillebon, A., Wu, I. H., Wahab, F., Dwyer, A., Kirsch, S., Quinton, R., Cheetham, T., Ozata, M., Ten, S., Chanoine, J. P. & 8 others, Pitteloud, N., Martin, K. A., Schiffmann, R., Van Der Kamp, H. J., Nader, S., Hall, J. E., Kaiser, U. B. & Seminara, S. B., Nov 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 11, p. E1771-E1781

Research output: Contribution to journalArticle

43 Scopus citations

Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle

Percival, J. M., Anderson, K. N. E., Huang, P., Adams, M. E. & Froehner, S. C., Mar 1 2010, In : Journal of Clinical Investigation. 120, 3, p. 816-826 11 p.

Research output: Contribution to journalArticle

91 Scopus citations

GPCR ontology: Development and application of a G protein-coupled receptor pharmacology knowledge framework

Przydzial, M. J., Bhhatarai, B., Koleti, A., Vempati, U., Schürer, S. C. & Wren, J., Dec 15 2013, In : Bioinformatics. 29, 24, p. 3211-3219 9 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

G-protein inhibition of phospholipase C-β1 in membranes: Role of G-protein βγ subunits

Litosch, I., Jan 1 1996, In : Biochemical Journal. 319, 1, p. 173-178 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

G protein-mediated inhibition of phospholipase C activity in a solubilized membrane preparation

Litosch, I., Sulkholutskaya, I. & Weng, C., Jan 1 1993, In : Journal of Biological Chemistry. 268, 12, p. 8692-8697 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
22 Scopus citations

G-protein βγ subunits antagonize protein kinase C-dependent phosphorylation and inhibition of phospholipase C-β1

Litosch, I., Sep 15 1997, In : Biochemical Journal. 326, 3, p. 701-707 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Growth cone pathfinding and filopodial dynamics are mediated separately by Cdc42 activation

Kim, M. D., Kolodziej, P. & Chiba, A., Mar 1 2002, In : Journal of Neuroscience. 22, 5, p. 1794-1806 13 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Growth cone steering by receptor tyrosine phosphatase δ defines a distinct class of guidance cue

Sun, Q. L., Wang, J., Bookman, R. J. & Bixby, J. L., Jan 1 2000, In : Molecular and Cellular Neuroscience. 16, 5, p. 686-695 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine With subacute ischemic cardiomyopathy

Bagno, L. L., Kanashiro-Takeuchi, R. M., Suncion, V. Y., Golpanian, S., Karantalis, V., Wolf, A., Wang, B., Premer, C., Balkan, W., Rodriguez, J., Valdes, D., Rosado, M., Block, N. L., Goldstein, P., Morales, A., Cai, R., Sha, W., Schally, A. V. & Hare, J. M., 2015, In : Journal of the American Heart Association. 4, 4, e001464.

Research output: Contribution to journalArticle

12 Scopus citations

GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation

Penas, C., Mishra, J. K., Wood, S. D., Schuerer, S. C., Roush, W. R. & Ayad, N., Feb 1 2015, In : Cell Cycle. 14, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

GSK3 involvement in amylin signaling in isolated rat soleus muscle

Abaffy, T. & Cooper, G. J. S., Dec 1 2004, In : Peptides. 25, 12, p. 2119-2125 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
11 Scopus citations

Guanine nucleotide and NaF stimulation of phospholipase C activity in rat cerebral-cortical membranes. Studies on substrate specificity

Litosch, I., Jan 1 1987, In : Biochemical Journal. 244, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Guanine nucleotides mediate stimulatory and inhibitory effects on cerebral-cortical membrane phospholipase C activity

Litosch, I., 1989, In : Biochemical Journal. 261, 1, p. 245-251 7 p.

Research output: Contribution to journalArticle

25 Scopus citations
82 Scopus citations

Gβ5-RGS7 inhibits Gαq-mediated signaling via a direct protein-protein interaction

Witherow, D. S., Tovey, S. C., Wang, Q., Willars, G. B. & Slepak, V. Z., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 21307-21313 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex

Karpinsky-Semper, D., Tayou, J., Levay, K., Schuchardt, B. J., Bhat, V., Volmar, C. H., Farooq, A. & Slepak, V. Z., Feb 3 2015, In : Biochemistry. 54, 4, p. 1077-1088 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis

Hu, X., Zhang, L., Jin, J., Zhu, W., Xu, Y., Wu, Y., Wang, Y., Chen, H., Webster, K. A., Chen, H., Yu, H. & Wang, J., Jun 1 2015, In : Stem Cells. 33, 6, p. 1850-1862 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Hepatocyte growth factor and vitamin D cooperatively inhibit androgen-unresponsive prostate cancer cell lines

Qadan, L. R., Perez-Stable, C. M., Schwall, R. H., Burnstein, K. L., Ostenson, R. C., Howard, G. A. & Roos, B. A., Jan 1 2000, In : Endocrinology. 141, 7, p. 2567-2573 7 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Hepatoma-derived growth factor-related protein-3 is a novel angiogenic factor

LeBlanc, M. E., Wang, W., Caberoy, N. B., Chen, X., Guo, F., Alvarado, G., Shen, C., Wang, F., Wang, H., Chen, R., Liu, Z. J., Webster, K. & Li, W., May 21 2015, In : PloS one. 10, 5, e0127904.

Research output: Contribution to journalArticle

11 Scopus citations

Heterogeneity in SDF-1 expression defines the vasculogenic potential of adult cardiac progenitor cells

Rodrigues, C. O., Shehadeh, L. A., Hoosien, M., Otero, V., Chopra, I., Tsinoremas, N. F. & Bishopric, N. H., Aug 24 2011, In : PloS one. 6, 8, e24013.

Research output: Contribution to journalArticle

11 Scopus citations

Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia

Poth, K., Nutter, T. J., Cuevas, J., Parker, M. J., Adams, D. J. & Luetje, C. W., Jan 20 1997, In : Journal of Neuroscience. 17, 2, p. 586-596 11 p.

Research output: Contribution to journalArticle

90 Scopus citations

High-content analysis of proapoptotic EphA4 dependence receptor functions using small-molecule libraries

Nelersa, C. M., Barreras, H., Runko, E., Ricard, J., Shi, Y., Glass, S. J., Bixby, J. L., Lemmon, V. P. & Liebl, D. J., Jul 2012, In : Journal of Biomolecular Screening. 17, 6, p. 785-795 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

High content screening of cortical neurons identifies novel regulators of axon growth

Blackmore, M. G., Moore, D. L., Smith, R. P., Goldberg, J. L., Bixby, J. L. & Lemmon, V. P., May 1 2010, In : Molecular and Cellular Neuroscience. 44, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

High quality, small molecule-activity datasets for kinase research [version 1; referees: 2 approved]

Sharma, R., Schuerer, S. C. & Muskal, S. M., 2016, In : F1000Research. 5, 1366.

Research output: Contribution to journalArticle

High quality, small molecule-activity datasets for kinase research [version 2; referees: 2 approved]

Sharma, R., Schuerer, S. C. & Muskal, S. M., 2016, In : F1000Research. 5, 1366.

Research output: Contribution to journalArticle

3 Scopus citations

High-throughput screening based identification of small molecule antagonists of integrin CD11b/CD18 ligand binding

Faridi, M. H., Maiguel, D., Brown, B. T., Suyama, E., Barth, C. J., Hedrick, M., Vasile, S., Sergienko, E., Schürer, S. & Gupta, V., Mar 26 2010, In : Biochemical and biophysical research communications. 394, 1, p. 194-199 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

High-throughput screening for human galactokinase inhibitors

Wierenga, K. J., Lai, K., Buchwald, P. & Tang, M., Aug 1 2008, In : Journal of Biomolecular Screening. 13, 5, p. 415-423 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

High tolerance for ionizable residues in the hydrophobic interior of proteins

Isom, D. G., Cannon, B. R., Castañeda, C. A., Robinson, A. & García-Moreno E., B., Nov 18 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 46, p. 17784-17788 5 p.

Research output: Contribution to journalArticle

106 Scopus citations

Hormonal Activation of Phosphoinositide Breakdown in the Presence of Guanine Nucleotides Using a Cell-Free System from Blowfly Salivary Glands

Fain, J. N. & Litosch, I., Jan 1987, In : Methods in enzymology. 141, C, p. 255-261 7 p.

Research output: Contribution to journalArticle

Hormonal regulation of malic enzyme and glucose-6-phosphate dehydrogenase in brown adipose tissue

Carvalho, S. D., Negrao, N. & Bianco, A. C., Jan 1 1993, In : American Journal of Physiology - Endocrinology and Metabolism. 264, 6 27-6, p. E874-E881

Research output: Contribution to journalArticle

28 Scopus citations

Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells

Almaça, J., Molina, J., Menegaz, D., Pronin, A. N., Tamayo, A., Slepak, V., Berggren, P-O. Y. & Caicedo, A., Dec 20 2016, In : Cell Reports. 17, 12, p. 3281-3291 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Human endometrial stem cells confer enhanced myocardial salvage and regeneration by paracrine mechanisms

Jiang, Z., Hu, X., Yu, H., Xu, Y., Wang, L., Chen, H., Chen, H., Wu, R., Zhang, Z., Xiang, C., Webster, K. A. & Wang, J. A., Oct 2013, In : Journal of Cellular and Molecular Medicine. 17, 10, p. 1247-1260 14 p.

Research output: Contribution to journalArticle

37 Scopus citations

Hydrophobic interaction between the monomer of mitochondrial malate dehydrogenase and phospholipid membranes.

Webster, K. A., Freeman, K. B. & Ohki, S., Jan 15 1980, In : The Biochemical journal. 186, 1, p. 227-233 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hyperactivated Stat3 boosts axon regeneration in the CNS

Mehta, S. T., Luo, X., Park, K. K., Bixby, J. L. & Lemmon, V. P., Jun 1 2016, In : Experimental neurology. 280, p. 115-120 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice

Yuan, C. C., Kazmierczak, K., Liang, J., Takeuchi, R., Irving, T. C., Gomes, A. V., Wang, Y., Burghardt, T. P. & Szczesna-Cordary, D., Aug 1 2017, In : Cardiovascular Research. 113, 10, p. 1124-1136 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice

Huang, W., Liang, J., Kazmierczak, K., Muthu, P., Duggal, D., Farman, G. P., Sorensen, L., Pozios, I., Abraham, T. P., Moore, J. R., Borejdo, J. & Szczesna-Cordary, D., Sep 2014, In : Journal of Molecular and Cellular Cardiology. 74, p. 318-329 12 p.

Research output: Contribution to journalArticle

18 Scopus citations