Molecular and Cellular Pharmacology

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Central role of brown adipose tissue thyroxine 5’-deiodinase on thyroid hormone-dependent thermogenic response to cold

Carvalho, S. D., Kimura, E. T., Bianco, A. C. & Enrique Silva, J., Apr 1991, In : Endocrinology. 128, 4, p. 2149-2159 11 p.

Research output: Contribution to journalArticle

73 Scopus citations

Challenges in small screening laboratories: Implementing an on-demand laboratory information management system

Lemmon, V. P., Jia, Y., Shi, Y., Holbrook, S. D., Bixby, J. L. & Buchser, W., Nov 1 2011, In : Combinatorial Chemistry and High Throughput Screening. 14, 9, p. 742-748 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
34 Scopus citations

Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells

Peschansky, V. J., Pastori, C., Zeier, Z. R., Motti, D., Wentzel, K., Velmeshev, D., Magistri, M., Bixby, J., Lemmon, V., Silva, J. P. & Wahlestedt, C. R., 2015, In : Frontiers in Genetics. 6, Aug, 263.

Research output: Contribution to journalArticle

14 Scopus citations

Chapter 8 Molecular and cellular stress pathways in ischemic heart disease: Targets for regulated gene therapy

Webster, K. A., Dec 1 2000, In : Cell and Molecular Response to Stress. 1, C, p. 99-112 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Characterisation of a mutant of barnacle troponin C lacking Ca2+- binding sites at positions II and IV

Allhouse, L. D., Guzman, G., Miller, T., Li, Q., Potter, J. D. & Ashley, C. C., Jun 7 1999, In : Pflugers Archiv European Journal of Physiology. 438, 1, p. 30-39 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Characterization of a Goα mutant that binds xanthine nucleotides

Yu, B., Slepak, V. Z. & Simon, M. I., Jul 18 1997, In : Journal of Biological Chemistry. 272, 29, p. 18015-18019 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Characterization of a vacuolar pyrophosphatase in Trypanosoma brucei and its localization to acidocalcisomes

Rodrigues, C. O., Scott, D. A. & Docampo, R., Nov 1 1999, In : Molecular and cellular biology. 19, 11, p. 7712-7723 12 p.

Research output: Contribution to journalArticle

78 Scopus citations

Characterization of ectophosphatase activities in trypanosomatid parasites of plants

Dutra, P. M. L., Rodrigues, C. O., Romeiro, A., Grillo, L. A. M., Dias, F. A., Attias, M., De Souza, W., Lopes, A. H. C. S. & Meyer-Fernandes, J. R., Jan 1 2000, In : Phytopathology. 90, 9, p. 1032-1038 7 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Characterization of isolated acidocalcisomes from Toxoplasma gondii tachyzoites reveals a novel pool of hydrolyzable polyphosphate

Rodrigues, C. O., Ruiz, F. A., Rohloff, P., Scott, D. A. & Moreno, S. N. J., Dec 13 2002, In : Journal of Biological Chemistry. 277, 50, p. 48650-48656 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Characterization of Tescalcin, a Novel EF-Hand Protein with a Single Ca2+-Binding Site: Metal-Binding Properties, Localization in Tissues and Cells, and Effect on Calcineurin

Gutierrez-Ford, C., Levay, K., Gomes, A. V., Perera, E. M., Som, T., Kim, Y. M., Benovic, J. L., Berkovitz, G. D. & Slepak, V. Z., Dec 16 2003, In : Biochemistry. 42, 49, p. 14553-14565 13 p.

Research output: Contribution to journalArticle

47 Scopus citations

Characterization of the Ca2+-regulatory complex of chick embryonic muscles: Polymorphism of tropomyosin in adult and embryonic fibers

Roy, R. K., Potter, J. D. & Sarkar, S., May 3 1976, In : Biochemical and biophysical research communications. 70, 1, p. 28-36 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform

Venkatraman, G., Gomes, A. V., Kerrick, W. G. L. & Potter, J. D., May 6 2005, In : Journal of Biological Chemistry. 280, 18, p. 17584-17592 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

Ince, T., Sousa, A. D., Jones, M. A., Harrell, J. C., Agoston, E. S., Krohn, M., Selfors, L. M., Liu, W., Chen, K., Yong, M., Buchwald, P., Wang, B., Hale, K. S., Cohick, E., Sergent, P., Witt, A., Kozhekbaeva, Z., Gao, S., Agoston, A. T., Merritt, M. A. & 5 others, Foster, R., Rueda, B. R., Crum, C. P., Brugge, J. S. & Mills, G. B., Jun 17 2015, In : Nature Communications. 6, 7419.

Research output: Contribution to journalArticle

73 Scopus citations

Characterization of yeast clathrin and anticlathrin heavy‐chain monoclonal antibodies

Lemmon, S. K., Lemmon, V. P. & Jones, E. W., Apr 1988, In : Journal of cellular biochemistry. 36, 4, p. 329-340 12 p.

Research output: Contribution to journalArticle

29 Scopus citations
18 Scopus citations

Chararacterization of G-protein α subunits in the Gq class: Expression in murine tissues and in stromal and hematopoietic cell lines

Wilkie, T. M., Scherle, P. A., Strathmann, M. P., Slepak, V. Z. & Simon, M. I., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 22, p. 10049-10053 5 p.

Research output: Contribution to journalArticle

Open Access
243 Scopus citations

Charges in the hydrophobic interior of proteins

Isom, D. G., Castañeda, C. A., Cannon, B. R., Velu, P. D. & García-Moreno E, B., Sep 14 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 37, p. 16096-16100 5 p.

Research output: Contribution to journalArticle

126 Scopus citations

Checkpoints in the cell cycle of fission yeast

D'Urso, G. & Nurse, P., Feb 1995, In : Current Opinion in Genetics and Development. 5, 1, p. 12-16 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
29 Scopus citations

Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients

Han, D., Berman, D. M., Willman, M., Buchwald, P., Rothen, D., Kenyon, N. M. & Kenyon, N. S., Dec 1 2010, In : Cell Transplantation. 19, 12, p. 1547-1561 15 p.

Research output: Contribution to journalArticle

10 Scopus citations

Chroman-3-amides as potent Rho kinase inhibitors

Chen, Y. T., Bannister, T. D., Weiser, A., Griffin, E., Lin, L., Ruiz, C., Cameron, M. D., Schürer, S., Duckett, D., Schröter, T., LoGrasso, P. & Feng, Y., Dec 15 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 24, p. 6406-6409 4 p.

Research output: Contribution to journalArticle

40 Scopus citations

Chronic cardiac-specific thyrotoxicosis increases myocardial β-adrenergic responsiveness

Carvalho-Bianco, S. D., Kim, B. W., Zhang, J. X., Harney, J. W., Ribeiro, R. S., Gereben, B., Bianco, A. C., Mende, U. & Larsen, P. R., Jul 1 2004, In : Molecular Endocrinology. 18, 7, p. 1840-1849 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Chronic Membrane Depolarization Regulates the Level of the Guanine Nucleotide Binding Protein Goα in Cultured Neuronal Cells

Luetje, C. W. & Nathanson, N. M., Jun 1988, In : Journal of neurochemistry. 50, 6, p. 1775-1782 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

C-Jun N-terminal kinase (JNK-1) confers protection against brief but not extended ischemia during acute myocardial infarction

Wei, J., Wang, W., Chopra, I., Li, H. F., Dougherty, C. J., Adi, J., Adi, N., Wang, H. & Webster, K. A., Apr 22 2011, In : Journal of Biological Chemistry. 286, 16, p. 13995-14006 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

CJun promotes CNS axon growth

Lerch, J. K., Martínez-Ondaro, Y. R., Bixby, J. L. & Lemmon, V. P., Mar 1 2014, In : Molecular and Cellular Neuroscience. 59, p. 97-105 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

CKit+ cardiac progenitors of neural crest origin

Hatzistergos, K. E., Takeuchi, L. M., Saur, D., Seidler, B., Dymecki, S. M., Mai, J. J., White, I. A., Balkan, W. E., Takeuchi, R., Schally, A. V. & Hare, J., Oct 20 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 42, p. 13051-13056 6 p.

Research output: Contribution to journalArticle

55 Scopus citations

C-kit+ cells isolated from developing kidneys are a novel population of stem cells with regenerative potential

Rangel, E. B., Gomes, S. A., Dulce, R. A., Premer, C., Rodrigues, C. O., Kanashiro-Takeuchi, R. M., Oskouei, B., Carvalho, D. A., Ruiz, P., Reiser, J. & Hare, J. M., Aug 1 2013, In : Stem Cells. 31, 8, p. 1644-1656 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Clathrin: A matter of life or death?

Lemmon, S. K. & Jones, E. W., Dec 1 1988, In : Science. 239, 4842, 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Clathrin functions in the absence of heterotetrameric adaptors and AP180-related proteins in yeast

Huang, K. M., D'Hondt, K., Riezman, H. & Lemmon, S. K., Jul 15 1999, In : EMBO Journal. 18, 14, p. 3897-3908 12 p.

Research output: Contribution to journalArticle

104 Scopus citations

Clathrin functions in the absence of the terminal domain binding site for adaptor-associated clathrin-box motifs

Collette, J. R., Chi, R. J., Boettner, D. R., Fernandez-Golbano, I. M., Plemel, R., Merz, A. J., Geli, M. I., Traub, L. M. & Lemmon, S. K., Jul 15 2009, In : Molecular biology of the cell. 20, 14, p. 3401-3413 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast

Newpher, T. M. & Lemmon, S. K., May 1 2006, In : Traffic. 7, 5, p. 574-588 15 p.

Research output: Contribution to journalArticle

47 Scopus citations

Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin

Boettner, D. R., Friesen, H., Andrews, B. & Lemmon, S. K., Oct 1 2011, In : Molecular biology of the cell. 22, 19, p. 3699-3714 16 p.

Research output: Contribution to journalArticle

30 Scopus citations

Clathrin requirement for normal growth of yeast

Lemmon, S. K. & Jones, E. W., Jan 1 1987, In : Science. 238, 4826, p. 504-509 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Clinical and functional Characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy

Hershberger, R. E., Pinto, J. R., Parks, S. B., Kushner, J. D., Li, D., Ludwigsen, S., Cowan, J., Morales, A., Parvatiyar, M. S. & Potter, J. D., Aug 1 2009, In : Circulation: Cardiovascular Genetics. 2, 4, p. 306-313 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

CLO: The cell line ontology

Sarntivijai, S., Lin, Y., Xiang, Z., Meehan, T. F., Diehl, A. D., Vempati, U. D., Schürer, S. C., Pang, C., Malone, J., Parkinson, H., Liu, Y., Takatsuki, T., Saijo, K., Masuya, H., Nakamura, Y., Brush, M. H., Haendel, M. A., Zheng, J., Stoeckert, C. J., Peters, B. & 5 others, Mungall, C. J., Carey, T. E., States, D. J., Athey, B. D. & He, Y., Aug 13 2014, In : Journal of Biomedical Semantics. 5, 1, 37.

Research output: Contribution to journalArticle

44 Scopus citations

c-Myc Is Essential to Prevent Endothelial Pro-Inflammatory Senescent Phenotype

Florea, V., Bhagavatula, N., Simovic, G., Macedo, F. Y., Fock, R. A. & Rodrigues, C. O., Sep 6 2013, In : PloS one. 8, 9, e73146.

Research output: Contribution to journalArticle

13 Scopus citations

Coactivator MYST1 regulates nuclear factor-κB and androgen receptor functions during proliferation of prostate cancer cells

Jaganathan, A., Chaurasia, P., Xiao, G. Q., Philizaire, M., Lv, X., Yao, S., Burnstein, K. L., Liu, D. P., Levine, A. C. & Mujtaba, S., Jun 2014, In : Molecular Endocrinology. 28, 6, p. 872-885 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Cognitive and motor abilities in preschool hydrocephalics

Thompson, N. M., Chapieski, L., Miner, M. E., Fletcher, J. M., Landry, S. H. & Bixby, J., Jan 1 1991, In : Journal of Clinical and Experimental Neuropsychology. 13, 2, p. 245-258 14 p.

Research output: Contribution to journalArticle

37 Scopus citations
9 Scopus citations

Comparative analysis of volatile metabolomics signals from melanoma and benign skin: A pilot study

Abaffy, T., Möller, M. G., Riemer, D. D., Milikowski, C. & DeFazio, R. A., Oct 1 2013, In : Metabolomics. 9, 5, p. 998-1008 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II)

Schröter, T., Minond, D., Weiser, A., Dao, C., Habel, J., Spicer, T., Chase, P., Baillargeon, P., Scampavia, L., Schürer, S., Chung, C., Mader, C., Southern, M., Tsinoremas, N., LoGrasso, P. & Hodder, P., Feb 1 2008, In : Journal of Biomolecular Screening. 13, 1, p. 17-28 12 p.

Research output: Contribution to journalArticle

35 Scopus citations
25 Scopus citations

Complexes of the G protein subunit Gβ5 with the regulators of G protein signaling RGS7 and RGS9. Characterization in native tissues and in transfected cells

Witherow, D. S., Wang, Q., Levay, K., Cabrera, J. L., Chen, J., Willars, G. B. & Slepak, V. Z., Aug 11 2000, In : Journal of Biological Chemistry. 275, 32, p. 24872-24880 9 p.

Research output: Contribution to journalArticle

123 Scopus citations

Comprehensive metabolomics study to assess longitudinal biochemical changes and potential early biomarkers in nonobese diabetic mice that progress to diabetes

Buchwald, P., Tamayo-Garcia, A., Ramamoorthy, S., Garcia-Contreras, M., Mendez, A. J. & Ricordi, C., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3873-3890 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

Computational modeling of substrate specificity and catalysis of the β-secretase (BACE1) enzyme

Barman, A., Schürer, S. & Prabhakar, R., May 24 2011, In : Biochemistry. 50, 20, p. 4337-4349 13 p.

Research output: Contribution to journalArticle

38 Scopus citations
Open Access

Conformational changes of F-actin in myosin-free ghost single fibre induced by either phosphorylated or dephosphorylated heavy meromyosin

Kâkol, I., Borovikov, Y. S., Szczêsna, D., Kirillina, V. P. & Levitsky, D. I., May 27 1987, In : Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 913, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Conserved rules govern genetic interaction degree across species

Koch, E. N., Costanzo, M., Bellay, J., Deshpande, R., Chatfield-Reed, K., Chua, G., D'Urso, G., Andrews, B. J., Boone, C. & Myers, C. L., Jul 2 2012, In : Genome biology. 13, 7, R57.

Research output: Contribution to journalArticle

28 Scopus citations

Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice

Yuan, C. C., Muthu, P., Kazmierczak, K., Liang, J., Huang, W., Irving, T. C., Takeuchi, R., Hare, J. & Szczesna-Cordary, D., Jul 28 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 30, p. E4138-E4146

Research output: Contribution to journalArticle

36 Scopus citations