Molecular and Cellular Pharmacology

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Single cardiac ventricular myosins are autonomous motors

Wang, Y., Yuan, C. C., Kazmierczak, K., Szczesna-Cordary, D. & Burghardt, T. P., Jan 1 2018, In : Open Biology. 4, 8, 170240.

Research output: Contribution to journalArticle

8 Scopus citations

Single molecule detection approach to muscle study: kinetics of a single cross-bridge during contraction of muscle.

Borejdo, J., Szczesna-Cordary, D., Muthu, P., Metticolla, P., Luchowski, R., Gryczynski, Z. & Gryczynski, I., Sep 11 2012, In : Methods in molecular biology (Clifton, N.J.). 875, p. 311-334 24 p.

Research output: Contribution to journalArticle

6 Scopus citations

Single molecule kinetics in the familial hypertrophic cardiomyopathy D166V mutant mouse heart

Muthu, P., Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., Szczesna-Cordary, D. & Borejdo, J., May 1 2010, In : Journal of Molecular and Cellular Cardiology. 48, 5, p. 989-998 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
14 Scopus citations

Slow-twitch skeletal muscle defects accompany cardiac dysfunction in transgenic mice with a mutation in the myosin regulatory light chain

Kazmierczak, K., Liang, J., Yuan, C. C., Yadav, S., Sitbon, Y. H., Walz, K., Ma, W., Irving, T. C., Cheah, J. X., Gomes, A. V. & Szczesna-Cordary, D., Mar 1 2019, In : FASEB Journal. 33, 3, p. 3152-3166 15 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Small-molecule costimulatory blockade: Organic dye inhibitors of the CD40-CD154 interaction

Margolles-Clark, E., Umland, O., Kenyon, N. S., Ricordi, C. & Buchwald, P., Nov 1 2009, In : Journal of Molecular Medicine. 87, 11, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction

Chen, J., Song, Y., Bojadzic, D., Tamayo-Garcia, A., Landin, A. M., Blomberg, B. B. & Buchwald, P., Nov 9 2017, In : Journal of Medicinal Chemistry. 60, 21, p. 8906-8922 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease

Maiguel, D., Faridi, M. H., Wei, C., Kuwano, Y., Balla, K. M., Hernandez, D., Barth, C. J., Lugo, G., Donnelly, M., Nayer, A., Moita, L. F., Schürer, S., Traver, D., Ruiz, P., Vazquez-Padron, R. I., Ley, K., Reiser, J. & Gupta, V., Sep 6 2011, In : Science Signaling. 4, 189

Research output: Contribution to journalArticle

57 Scopus citations

Small-molecule modulators of the OX40OX40 ligand co-stimulatory proteinprotein interaction

Song, Y., Margolles-Clark, E., Bayer, A. & Buchwald, P., Nov 2014, In : British Journal of Pharmacology. 171, 21, p. 4955-4969 15 p.

Research output: Contribution to journalArticle

16 Scopus citations

S-nitrosoglutathione reductase (GSNOR) enhances vasculogenesis by mesenchymal stem cells

Gomes, S. A., Rangel, E. B., Premer, C., Dulce, R. A., Cao, Y., Florea, V., Balkan, W., Rodrigues, C. O., Schally, A. V. & Hare, J. M., Feb 19 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 8, p. 2834-2839 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

S-Nitrosoglutathione Reductase Deficiency Enhances the Proliferative Expansion of Adult Heart Progenitors and Myocytes Post Myocardial Infarction

Hatzistergos, K. E., Paulino, E. C., Dulce, R. A., Takeuchi, L. M., Bellio, M. A., Kulandavelu, S., Cao, Y., Balkan, W. E., Takeuchi, R. & Hare, J., Jul 15 2015, In : Journal of the American Heart Association. 4, 7

Research output: Contribution to journalArticle

25 Scopus citations

Soft corticosteroids for local immunosuppression: Exploring the possibility for the use of loteprednol etabonate for islet transplantation

Bocca, N., Pileggi, A., Molano, R. D., Marzorati, S., Wu, W., Bodor, N., Ricordi, C. & Buchwald, P., Mar 1 2008, In : Pharmazie. 63, 3, p. 226-232 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Soft glucocorticoid design: Structural elements and physicochemical parameters determining receptor-binding affinity

Buchwald, P. & Bodor, N., May 1 2004, In : Pharmazie. 59, 5, p. 396-404 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
16 Scopus citations

Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5

Nuñez, I., Pino, M. R., Wiley, D. J., Das, M. E., Chen, C., Goshima, T., Kume, K., Hirata, D., Toda, T. & Verde, F., Jul 30 2016, In : eLife. 5, JULY, e14216.

Research output: Contribution to journalArticle

7 Scopus citations

Specific involvement of calmodulin and non‐specific effect of tropomyosin in the sensitivity to ouabain of Na+, K+‐ATPase in murine plasmocytoma cells

LELIEVRE, L. G., POTTER, J. D., PIASCIK, M., WALLICK, E. T., SCHWARTZ, A., CHARLEMAGNE, D. & GENY, B., Apr 1985, In : European Journal of Biochemistry. 148, 1, p. 13-19 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome

Li, C., Brazill, J. M., Liu, S., Bello, C., Zhu, Y., Morimoto, M., Cascio, L., Pauly, R., Diaz-Perez, Z., Malicdan, M. C. V., Wang, H., Boccuto, L., Schwartz, C. E., Gahl, W. A., Boerkoel, C. F. & Zhai, R. G., Dec 1 2017, In : Nature Communications. 8, 1, 1257.

Research output: Contribution to journalArticle

17 Scopus citations

Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats

Hausmann, O. N., Hu, W. H., Keren-Raifman, T., Witherow, D. S., Wang, Q., Levay, K., Frydel, B., Slepak, V. Z. & Bethea, J. R., Dec 31 2002, In : European Journal of Neuroscience. 15, 4, p. 602-612 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Spin labeling studies on the calcium receptor protein of troponin

Potter, J. D., Seidel, J. C. & Gergely, J., Jan 1 1973, In : Federation Proceedings. 32, 3 I, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Stability and function of a putative microtubule-organizing center in the human parasite Toxoplasma gondii

Leung, J. M., He, Y., Zhang, F., Hwang, Y. C., Nagayasu, E., Liu, J., Murray, J. M. & Hu, K., May 15 2017, In : Molecular biology of the cell. 28, 10, p. 1361-1378 18 p.

Research output: Contribution to journalArticle

8 Scopus citations

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy

Parvatiyar, M. S., Brownstein, A. J., Takeuchi, R., Collado, J. R., Dieseldorff Jones, K. M., Gopal, J., Hammond, K. G., Marshall, J. L., Ferrel, A., Beedle, A. M., Chamberlain, J. S., Pinto, J. R. & Crosbie, R. H., Jun 6 2019, In : JCI Insight. 4, 11, e123855.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Standardization of cardiac troponin I assays: Round robin of ten candidate reference materials

Christenson, R. H., Show Hong Duh, H. D., Apple, F. S., Bodor, G. S., Bunk, D. M., Dalluge, J., Panteghini, M., Potter, J. D., Welch, M. J., Wu, A. H. B. & Kahn, S. E., Mar 28 2001, In : Clinical chemistry. 47, 3, p. 431-437 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Stem cell factor improves lung recovery in rats following neonatal hyperoxia-induced lung injury

Miranda, L. F., Rodrigues, C. O., Ramachandran, S., Torres, E., Huang, J., Klim, J., Hehre, D., McNiece, I., Hare, J. M., Suguihara, C. Y. & Young, K. C., Dec 1 2013, In : Pediatric Research. 74, 6, p. 682-688 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Stereoisomers of N-substituted soft anticholinergics and their zwitterionic metabolite based on glycopyrrolate - Syntheses and pharmacological evaluations

Wu, W. M., Wu, J., Mori, N., Buchwald, P. & Bodor, N., Mar 1 2008, In : Pharmazie. 63, 3, p. 200-209 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Stress increases peripheral axon growth and regeneration through glucocorticoid receptor-dependent transcriptional programs

Lerch, J. K., Alexander, J. K., Madalena, K. M., Motti, D., Quach, T., Dhamija, A., Zha, A., Gensel, J. C., Marketon, J. W., Lemmon, V. P., Bixby, J. L. & Popovich, P. G., Jul 1 2017, In : eNeuro. 4, 4, e0246-17.2017.

Research output: Contribution to journalArticle

8 Scopus citations

Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia

Reiter, J., Drummond, S., Sammour, I., Huang, J., Florea, V., Dornas, P., Hare, J. M., Rodrigues, C. O. & Young, K. C., Jul 12 2017, In : Respiratory research. 18, 1, 137.

Research output: Contribution to journalArticle

16 Scopus citations

Strong cross-bridges potentiate the Ca2+ affinity changes produced by hypertrophic cardiomyopathy cardiac troponin C mutants in myofilaments: A fast kinetic approach

Pinto, J. R., Reynaldo, D. P., Parvatiyar, M. S., Dweck, D., Liang, J., Jones, M. A., Sorenson, M. M. & Potter, J. D., Jan 14 2011, In : Journal of Biological Chemistry. 286, 2, p. 1005-1013 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Structural and functional aspects of the myosin essential light chain in cardiac muscle contraction

Muthu, P., Wang, L., Yuan, C. C., Kazmierczak, K., Huang, W., Hernandez, O. M., Kawai, M., Irving, T. C. & Szczesna-Cordary, D., Dec 1 2011, In : FASEB Journal. 25, 12, p. 4394-4405 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Structural basis for calcium-induced inhibition of rhodopsin kinase by recoverin

Ames, J. B., Levay, K., Wingard, J. N., Lusin, J. D. & Slepak, V. Z., Dec 1 2006, In : Journal of Biological Chemistry. 281, 48, p. 37237-37245 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Structural determinants for phosphatidic acid regulation of phospholipase C-β1

Ross, E. M., Mateu, D., Gomes, A. V., Arana, C., Tran, T. & Litosch, I., Nov 3 2006, In : Journal of Biological Chemistry. 281, 44, p. 33087-33094 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Structural studies on the calcium receptor protein of troponin: the cyanogen bromide peptides

Collins, J. H. & Potter, J. D., Jan 1 1973, In : Federation Proceedings. 32, 3 I, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Structural studies on the chiral selector capacity of cyclodextrin derivatives.

Tokés, B., Ferencz, L., Buchwald, P., Donáth-Nagy, G., Vancea, S., Sánta, N. & Kis, E. L., Apr 24 2008, In : Journal of biochemical and biophysical methods. 70, 6, p. 1276-1282 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Structure-fluorescence correlations in a single tryptophan mutant of carp parvalbumin: Solution structure, backbone and side-chain dynamics

Moncrieffe, M. C., Juranić, N., Kemple, M. D., Potter, J. D., Macura, S. & Prendergast, F. G., Mar 17 2000, In : Journal of molecular biology. 297, 1, p. 147-163 17 p.

Research output: Contribution to journalArticle

34 Scopus citations
7 Scopus citations

Studies on phosphorylation of canine cardiac sarcoplasmic reticulum by calmodulin-dependent protein kinase

Bilezikjian, L. M., Kranias, E. G., Potter, J. D. & Schwartz, A., Jan 1 1981, In : Circulation research. 49, 6, p. 1356-1362 7 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations

Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells

Liapis, E., Sandiford, S., Wang, Q., Gaidosh, G., Motti, D., Levay, K. & Slepak, V. Z., Aug 1 2012, In : Journal of neurochemistry. 122, 3, p. 568-581 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Subunit contributions to insect olfactory receptor function: Channel block and odorant recognition

Nichols, A. S., Chen, S. & Luetje, C. W., Nov 1 2011, In : Chemical senses. 36, 9, p. 781-790 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Subunit contributions to phosphorylation-dependent modulation of bovine rod cyclic nucleotide-gated channels

Molokanova, E., Krajewski, J. L., Satpaev, D., Luetje, C. W. & Kramer, R. H., Oct 15 2003, In : Journal of Physiology. 552, 2, p. 345-356 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Subunit-dependent modulation of neuronal nicotinic receptors by zinc

Hsiao, B., Dweck, D. & Luetje, C. W., Mar 15 2001, In : Journal of Neuroscience. 21, 6, p. 1848-1856 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Subunit dissociation and diffusion determine the subcellular localization of rod and cone transducins

Rosenzweig, D. H., Saidas Nair, K., Wei, J., Wang, Q., Garwin, G., Saari, J. C., Chen, C. K., Smrcka, A. V., Swaroop, A., Lem, J., Hurley, J. B. & Slepak, V. Z., May 16 2007, In : Journal of Neuroscience. 27, 20, p. 5484-5494 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Suppression of TH 17 differentiation and autoimmunity by a synthetic ROR ligand

Solt, L. A., Kumar, N., Nuhant, P., Wang, Y., Lauer, J. L., Liu, J., Istrate, M. A., Kamenecka, T. M., Roush, W. R., Vidović, D., Schürer, S. C., Xu, J., Wagoner, G., Drew, P. D., Griffin, P. R. & Burris, T. P., Apr 28 2011, In : Nature. 472, 7344, p. 491-494 4 p.

Research output: Contribution to journalArticle

317 Scopus citations

Suramin inhibits the CD40-CD154 costimulatory interaction: A possible mechanism for immunosuppressive effects

Margolles-Clark, E., Jacques-Silva, M. C., Ganesan, L., Umland, O., Kenyon, N. S., Ricordi, C., Berggren, P-O. Y. & Buchwald, P., Apr 1 2009, In : Biochemical Pharmacology. 77, 7, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Sustainable data and metadata management at the BD2K-LINCS Data coordination and integration center

Stathias, V., Koleti, A., Vidovic, D., Cooper, D. J., Jagodnik, K. M., Terryn, R., Forlin, M., Chung, C., Torre, D., Ayad, N., Medvedovic, M., Ma'Ayan, A., Pillai, A. & Schuerer, S. C., Jun 19 2018, In : Scientific data. 5, 180117.

Research output: Contribution to journalArticle

9 Scopus citations

Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating

Verstreken, P., Koh, T. W., Schulze, K. L., Zhai, R. G., Hiesinger, P. R., Zhou, Y., Mehta, S. Q., Cao, Y., Roos, J. & Bellen, H. J., Nov 13 2003, In : Neuron. 40, 4, p. 733-748 16 p.

Research output: Contribution to journalArticle

262 Scopus citations

Synergistic activation of rat hepatocyte glycogen phosphorylase by A23187 and phorbol ester

Fain, J. N., Li, S. Y., Litosch, I. & Wallace, M., Feb 29 1984, In : Biochemical and biophysical research communications. 119, 1, p. 88-94 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Synergistic induction of miR-126 by hypoxia and HDAC inhibitors in cardiac myocytes

Shi, H., Chen, L., Wang, H., Zhu, S., Dong, C., Webster, K. A. & Wei, J., Jan 11 2013, In : Biochemical and biophysical research communications. 430, 2, p. 827-832 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues

Ondachi, P. W., Castro, A. H., Luetje, C. W., Wageman, C. R., Marks, M. J., Damaj, M. I., Mascarella, S. W., Navarro, H. A. & Carroll, F. I., Jul 20 2016, In : ACS Chemical Neuroscience. 7, 7, p. 1004-1012 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2′-fluoro-3′-(substituted pyridinyl)-7- deschloroepibatidine analogues

Ondachi, P. W., Castro, A. H., Bartkowiak, J. M., Luetje, C. W., Damaj, M. I., Mascarella, S. W., Navarro, H. A. & Carroll, F. I., Feb 13 2014, In : Journal of Medicinal Chemistry. 57, 3, p. 836-848 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

Ondachi, P. W., Castro, A. H., Sherman, B., Luetje, C. W., Damaj, M. I., Mascarella, S. W., Navarro, H. A. & Carroll, F. I., Jan 18 2017, In : ACS Chemical Neuroscience. 8, 1, p. 115-127 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs

Ondachi, P. W., Ye, Z., Castro, A. H., Luetje, C. W., Damaj, M. I., Mascarella, S. W., Navarro, H. A. & Carroll, F. I., May 22 2015, In : Bioorganic and Medicinal Chemistry. 23, 17, p. 5693-5701 9 p.

Research output: Contribution to journalArticle

1 Scopus citations