Molecular and Cellular Pharmacology

Research Output

2004

Getting past the asterisk: The subunit composition of presynaptic nicotinic receptors that modulate striatal dopamine release

Luetje, C. W., Jun 1 2004, In : Molecular Pharmacology. 65, 6, p. 1333-1335 3 p.

Research output: Contribution to journalReview article

33 Scopus citations

Glycosaminoglycan-dependent and -independent inhibition of neurite outgrowth by agrin

Baerwald-De La Torre, K., Winzen, U., Halfter, W. & Bixby, J. L., Jul 1 2004, In : Journal of neurochemistry. 90, 1, p. 50-61 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

GSK3 involvement in amylin signaling in isolated rat soleus muscle

Abaffy, T. & Cooper, G. J. S., Dec 1 2004, In : Peptides. 25, 12, p. 2119-2125 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hormone resistance: It's SMRT to fight repression

Burnstein, K. L. & Luetje, C. W., Apr 1 2004, In : Endocrinology. 145, 4, p. 1525-1526 2 p.

Research output: Contribution to journalShort survey

1 Scopus citations

Identification and cloning of two putative subunits of DNA polymerase epsilon in fussion yeast

Spiga, M. G. & D'Urso, G., Nov 9 2004, In : Nucleic acids research. 32, 16, p. 4945-4953 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Metabolic properties of phosphonate esters

Somogyi, G., Buchwald, P. & Bodor, N., May 1 2004, In : Pharmazie. 59, 5, p. 378-381 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mice with Targeted Disruption of the Dio2 Gene Have Cold-Induced Overexpression of the Uncoupling Protein 1 Gene but Fail to Increase Brown Adipose Tissue Lipogenesis and Adaptive Thermogenesis

Christoffolete, M. A., Linardi, C. C. G., De Jesus, L., Ebina, K. N., Carvalho, S. D., Ribeiro, M. O., Rabelo, R., Curcio, C., Martins, L., Kimura, E. T. & Bianco, A. C., Mar 1 2004, In : Diabetes. 53, 3, p. 577-584 8 p.

Research output: Contribution to journalArticle

140 Scopus citations

Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation

Dougherty, C. J., Kubasiak, L. A., Frazier, D. P., Li, H., Xiong, W. C., Bishopric, N. H. & Webster, K. A., Jul 1 2004, In : FASEB Journal. 18, 10, p. 1060-1070 11 p.

Research output: Contribution to journalArticle

81 Scopus citations

Molecular and cellular aspects of troponin cardiomyopathies

Gomes, A. V. & Potter, J. D., Jan 1 2004, In : Annals of the New York Academy of Sciences. 1015, p. 214-224 11 p.

Research output: Contribution to journalArticle

84 Scopus citations

Nitric oxide and promotion of cardiac myocyte apoptosis

Andréka, P., Tran, T., Webster, K. A. & Bishopric, N. H., Aug 1 2004, In : Molecular and Cellular Biochemistry. 263, 1, p. 35-53 19 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pancreatic cancer cells express 25-hydroxyvitamin D-1α-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3

Schwartz, G. G., Eads, D., Rao, A., Cramer, S. D., Willingham, M. C., Chen, T. C., Jamieson, D. P., Wang, L., Burnstein, K. L., Holick, M. F. & Koumenis, C., Jun 1 2004, In : Carcinogenesis. 25, 6, p. 1015-1026 12 p.

Research output: Contribution to journalArticle

88 Scopus citations

Programmed cell death in fission yeast

Rodriguez-Menocal, L. & D'Urso, G., Nov 1 2004, In : FEMS Yeast Research. 5, 2, p. 111-117 7 p.

Research output: Contribution to journalShort survey

15 Scopus citations

Regulation of a formin complex by the microtubule plus end protein tea1p

Feierbach, B., Verde, F. & Chang, F., Jun 7 2004, In : Journal of Cell Biology. 165, 5, p. 697-707 11 p.

Research output: Contribution to journalArticle

97 Scopus citations

Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels

Turner, M. S., Haywood, G. A., Andreka, P., You, L., Martin, P. E., Evans, W. H., Webster, K. A. & Bishopric, N. H., Oct 1 2004, In : Circulation research. 95, 7, p. 726-733 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

Role of troponin T in disease

Gomes, A. V., Barnes, J. A., Harada, K. & Potter, J. D., Aug 1 2004, In : Molecular and Cellular Biochemistry. 263, 1, p. 115-129 15 p.

Research output: Contribution to journalReview article

51 Scopus citations

Soft glucocorticoid design: Structural elements and physicochemical parameters determining receptor-binding affinity

Buchwald, P. & Bodor, N., May 1 2004, In : Pharmazie. 59, 5, p. 396-404 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Targeting of a Tropomyosin Isoform to Short Microfilaments Associated with the Golgi Complex

Percival, J. M., Hughes, J. A. I., Brown, D. L., Schevzov, G., Heimann, K., Vrhovski, B., Bryce, N., Stow, J. L. & Gunning, P. W., Jan 1 2004, In : Molecular biology of the cell. 15, 1, p. 268-280 13 p.

Research output: Contribution to journalArticle

73 Scopus citations

Thyroid hormone and adrenergic signaling in the heart.

Kim, B., Carvalho-Bianco, S. D. & Larsen, P. R., Feb 2004, In : Arquivos brasileiros de endocrinologia e metabologia. 48, 1, p. 171-175 5 p.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations

Variation in the antiandrogenic activity of diesel exhaust particulates emitted under different engine loads

Okamura, K., Kizu, R., Hayakawa, K., Toriba, A., Mizokami, A., Burnstein, K. L., Klinge, C. M. & Kato, S., Aug 1 2004, In : Polycyclic Aromatic Compounds. 24, 4-5, p. 743-757 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
2005

Adenoviral delivery of vegf promotes short term angiogenic effect

Gounis, M. J., Lieber, B. B., Webster, K. A., Spiga, M. G., Bishopric, N. H. & Wakhloo, A. K., Dec 1 2005, Proceedings of the 2005 Summer Bioengineering Conference, 2005 SBC. p. 709-710 2 p. (Proceedings of the 2005 Summer Bioengineering Conference; vol. 2005).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

45 Scopus citations
21 Scopus citations

Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle

Gounis, M. J., Spiga, M. G., Graham, R. M., Wilson, A., Haliko, S., Lieber, B. B., Wakhloo, A. K. & Webster, K. A., May 1 2005, In : Gene Therapy. 12, 9, p. 762-771 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth

Chen, B. & Bixby, J. L., Feb 26 2005, In : Journal of Neuroscience. 25, 4, p. 880-888 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

A routine electrocardiogram should not be used to determine the size of myocardial infarction in the rat

Bonilha, A. M. M., Saraiva, R. M., Kanashiro, R. M., Portes, L. A., Antonio, E. L. & Tucci, P. J. F., Apr 2005, In : Brazilian Journal of Medical and Biological Research. 38, 4, p. 615-619 5 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

BNip3 and signal-specific programmed death in the heart

Webster, K. A., Graham, R. M. & Bishopric, N. H., Jan 1 2005, In : Journal of Molecular and Cellular Cardiology. 38, 1, p. 35-45 11 p.

Research output: Contribution to journalReview article

76 Scopus citations

Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform

Venkatraman, G., Gomes, A. V., Kerrick, W. G. L. & Potter, J. D., May 6 2005, In : Journal of Biological Chemistry. 280, 18, p. 17584-17592 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Co-translational protein aggregation after transient cerebral ischemia

Liu, C. L., Ge, P., Zhang, F. & Hu, B. R., Sep 5 2005, In : Neuroscience. 134, 4, p. 1273-1284 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: A new intracellular target for matrix metalloproteinase-2

Sawicki, G., Leon, H., Sawicka, J., Sariahmetoglu, M., Schulze, C. J., Scott, P. G., Szczesna-Cordary, D. & Schulz, R., Jul 26 2005, In : Circulation. 112, 4, p. 544-552 9 p.

Research output: Contribution to journalArticle

206 Scopus citations

Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein

Cho, H. M., Rosenblatt, J. D., Kang, Y. S., Iruela-Arispe, M. L., Morrison, S. L., Penichet, M. L., Kwon, Y. G., Kim, T. W., Webster, K. A., Nechustan, H. & Shin, S. U., Jun 1 2005, In : Molecular cancer therapeutics. 4, 6, p. 956-967 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Expanding the range of free calcium regulation in biological solutions

Dweck, D., Reyes-Alfonso, A. & Potter, J. D., Dec 15 2005, In : Analytical Biochemistry. 347, 2, p. 303-315 13 p.

Research output: Contribution to journalArticle

58 Scopus citations

Expression of neuronal markers suggests heterogeneity of chick sympathoadrenal cells prior to invasion of the adrenal anlagen

Ernsberger, U., Esposito, L., Partimo, S., Huber, K., Franke, A., Bixby, J. L., Kalcheim, C. & Unsicker, K., Jan 1 2005, In : Cell and Tissue Research. 319, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers

Hernandez, O. M., Szczesna-Cordary, D., Knollmann, B. C., Miller, T., Bell, M., Zhao, J., Sirenko, S. G., Diaz, Z., Guzman, G., Xu, Y., Wang, Y., Kerrick, W. G. L. & Potter, J. D., Nov 4 2005, In : Journal of Biological Chemistry. 280, 44, p. 37183-37194 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis

Kanai, M., Kume, K., Miyahara, K., Sakai, K., Nakamura, K., Leonhard, K., Wiley, D. J., Verde, F., Toda, T. & Hirata, D., Sep 1 2005, In : EMBO Journal. 24, 17, p. 3012-3025 14 p.

Research output: Contribution to journalArticle

55 Scopus citations

Functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in α-tropomyosin

Chang, A. N., Harada, K., Ackerman, M. J. & Potter, J. D., Oct 7 2005, In : Journal of Biological Chemistry. 280, 40, p. 34343-34349 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

General linearized biexponential model for QSAR data showing bilinear-type distribution

Buchwald, P., Nov 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2355-2379 25 p.

Research output: Contribution to journalArticle

27 Scopus citations

In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast

Newpher, T. M., Smith, R. P., Lemmon, V. & Lemmon, S. K., Jul 1 2005, In : Developmental Cell. 9, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

143 Scopus citations

Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions

Nair, K. S., Hanson, S. M., Mendez, A., Gurevich, E. V., Kennedy, M. J., Shestopalov, V. I., Vishnivetskiy, S. A., Chen, J., Hurley, J. B., Gurevich, V. V. & Slepak, V. Z., May 19 2005, In : Neuron. 46, 4, p. 555-567 13 p.

Research output: Contribution to journalArticle

143 Scopus citations

Listeria's right-handed helical rocket-tail trajectories: Mechanistic implications for force generation in actin-based motility

Zeile, W. L., Zhang, F., Dickinson, R. B. & Purich, D. L., Feb 1 2005, In : Cell Motility and the Cytoskeleton. 60, 2, p. 121-128 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Modest actomyosin energy conservation increases myocardial postischemic function

Blunt, B. C., Chen, Y., Potter, J. D. & Hofmann, P. A., Mar 1 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 288, 3 57-3, p. H1088-H1096

Research output: Contribution to journalArticle

6 Scopus citations

Motor neurite outgrowth is selectively inhibited by cell surface MuSK and agrin

Dimitropoulou, A. & Bixby, J. L., Feb 2005, In : Molecular and Cellular Neuroscience. 28, 2, p. 292-302 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components

Mehta, S. Q., Hiesinger, P. R., Beronja, S., Zhai, R. G., Schulze, K. L., Verstreken, P., Cao, Y., Zhou, Y., Tepass, U., Crair, M. C. & Bellen, H. J., Apr 21 2005, In : Neuron. 46, 2, p. 219-232 14 p.

Research output: Contribution to journalArticle

107 Scopus citations

Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force development

Gomes, A. V., Liang, J. & Potter, J. D., Sep 2 2005, In : Journal of Biological Chemistry. 280, 35, p. 30909-30915 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Neuronal pentraxin with chromo domain (NPCD) is a novel class of protein expressed in multiple neuronal domains

Chen, B. & Bixby, J. L., Jan 24 2005, In : Journal of Comparative Neurology. 481, 4, p. 391-402 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Ophthalmic drug design based on the metabolic activity of the eye: Soft drugs and chemical delivery systems

Bodor, N. & Buchwald, P., Dec 28 2005, In : AAPS Journal. 7, 4, 79.

Research output: Contribution to journalReview article

75 Scopus citations

Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics

Wu, W. M., Buchwald, P., Mori, N., Ji, F., Wu, J. X. & Bodor, N., Dec 1 2005, In : Pharmaceutical Research. 22, 12, p. 2035-2044 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prospective exploration of synthetically feasible, medicinally relevant chemical space

Schürer, S. C., Tyagi, P. & Muskal, S. M., Mar 1 2005, In : Journal of Chemical Information and Modeling. 45, 2, p. 239-248 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
10 Scopus citations

RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation

Cheng, L., Lemmon, S. & Lemmon, V., Aug 1 2005, In : Journal of neurochemistry. 94, 4, p. 1102-1110 9 p.

Research output: Contribution to journalArticle

74 Scopus citations

Receptor tyrosine phosphatases guide vertebrate motor axons during development

Stepanek, L., Stoker, A. W., Stoeckli, E. & Bixby, J. L., Apr 13 2005, In : Journal of Neuroscience. 25, 15, p. 3813-3823 11 p.

Research output: Contribution to journalArticle

74 Scopus citations