Molecular and Cellular Pharmacology

Research Output

Correction: Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit (PLoS ONE (2017) 12:5 (e0177454) DOI: 10.1371/journal.pone.0177454)

Kepchia, D., Moliver, S., Chohan, K., Phillips, C. & Luetje, C. W., Aug 1 2017, In : PLoS One. 12, 8, e0183009.

Research output: Contribution to journalComment/debate

Correction to: In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice (Diabetologia, (2019), 62, 7, (1237-1250), 10.1007/s00125-019-4879-0)

Abdulreda, M. H., Molano, R. D., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. S., Ricordi, C., Caicedo, A., Buchwald, P., Pileggi, A. & Berggren, P. O., Jan 1 2019, In : Diabetologia.

Research output: Contribution to journalComment/debate

Correspondence

Potter, J. D., Kerrick, W. G. & Gulati, J., Jun 1 1992, In : Journal of Muscle Research and Cell Motility. 13, 3, p. 381-382 2 p.

Research output: Contribution to journalLetter

Correspondence re: Letter

Schwartz, G. G., Lokeshwar, B. L. & Burnstein, K. L., May 15 2001, In : Cancer Research. 61, 10, p. 4294 1 p.

Research output: Contribution to journalLetter

Cortical recruitment and nuclear-cytoplasmic shuttling of Scd5p, a protein phosphatase-1-targeting protein involved in actin organization and endocytosis

Chang, J. S., Henry, K., Geli, M. I. & Lemmon, S. K., Jan 1 2006, In : Molecular biology of the cell. 17, 1, p. 251-262 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Corticosteroid design for the treatment of asthma: Structural insights and the therapeutic potential of soft corticosteroids

Bodor, N. & Buchwald, P., Sep 1 2006, In : Current Pharmaceutical Design. 12, 25, p. 3241-3260 20 p.

Research output: Contribution to journalReview article

45 Scopus citations

Co-translational protein aggregation after transient cerebral ischemia

Liu, C. L., Ge, P., Zhang, F. & Hu, B. R., Sep 5 2005, In : Neuroscience. 134, 4, p. 1273-1284 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Creating a chimeric clathrin heavy chain that functions independently of yeast clathrin light chain

Boettner, D. R., Segarra, V. A., Moorthy, B. T., de León, N., Creagh, J., Collette, J. R., Malhotra, A. & Lemmon, S., Jul 1 2016, In : Traffic. 17, 7, p. 754-768 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

CREB-activity and NMNAT2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

Ljungberg, M. C., Ali, Y. O., Zhu, J., Wu, C. S., Oka, K., Zhai, R. G. & Lu, H. C., Jan 1 2012, In : Human molecular genetics. 21, 2, p. 251-267 17 p., ddr492.

Research output: Contribution to journalArticle

65 Scopus citations

Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin

Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., Zhao, J., Szczesna-Cordary, D. & Borejdo, J., Sep 7 2011, In : Journal of theoretical biology. 284, 1, p. 71-81 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

CRYP-2: A receptor-type tyrosine phosphatase selectively expressed by developing vertebrate neurons

Bodden, K. & Bixby, J. L., Nov 1 1996, In : Journal of Neurobiology. 31, 3, p. 309-324 16 p.

Research output: Contribution to journalArticle

34 Scopus citations

CRYP-2/cPTPRO is a neurite inhibitory repulsive guidance cue for retinal neurons in vitro

Stepanek, L., Sun, Q. L., Wang, J., Wang, C. & Bixby, J. L., Aug 20 2001, In : Journal of Cell Biology. 154, 4, p. 867-878 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Current and Future Challenges for Collaborative Computational Technologies for the Life Sciences

Williams, A. J., Arnold, R. J. G., Neylon, C., Spencer, R. W., Schürer, S. & Ekins, S., May 3 2011, Collaborative Computational Technologies for Biomedical Research. John Wiley and Sons, p. 491-518 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Cyclin A is required at two points in the human cell cycle

Pagano, M., Pepperkok, R., Verde, F., Ansorge, W. & Draetta, G., Jan 1 1992, In : EMBO Journal. 11, 3, p. 961-971 11 p.

Research output: Contribution to journalArticle

1030 Scopus citations

Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis

Andreka, P., Zang, J., Dougherty, C., Slepak, T. I., Webster, K. A. & Bishopric, N. H., Feb 16 2001, In : Circulation research. 88, 3, p. 305-312 8 p.

Research output: Contribution to journalArticle

Open Access
112 Scopus citations

Dansylaziridine-labeled troponin C. A fluorescent probe of Ca2+ binding to the Ca2+-specific regulatory sites

Johnson, J. D., Collins, J. H. & Potter, J. D., Dec 1 1978, In : Journal of Biological Chemistry. 253, 18, p. 6451-6458 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: Integrated access to diverse large-scale cellular perturbation response data

Koleti, A., Terryn, R., Stathias, V., Chung, C., Cooper, D. J., Turner, J. P., VidoviÄ ‡, D., Forlin, M., Kelley, T. T., D'Urso, A., Allen, B. K., Torre, D., Jagodnik, K. M., Wang, L., Jenkins, S. L., Mader, C., Niu, W., Fazel, M., Mahi, N., Pilarczyk, M. & 9 others, Clark, N., Shamsaei, B., Meller, J., Vasiliauskas, J., Reichard, J., Medvedovic, M., Ma'Ayan, A., Pillai, A. & Schürer, S. C., Jan 1 2018, In : Nucleic Acids Research. 46, D1, p. D558-D566

Research output: Contribution to journalArticle

35 Scopus citations

Dealing with misfolded proteins: Examining the neuroprotective role of molecular chaperones in neurodegeneration

Ali, Y. O., Kitay, B. M. & Zhai, R. G., Oct 1 2010, In : Molecules. 15, 10, p. 6859-6887 29 p.

Research output: Contribution to journalReview article

30 Scopus citations

Defective CXCR4 expression in aged bone marrow cells impairs vascular regeneration

Shao, H., Xu, Q., Wu, Q., Ma, Q., Salgueiro, L., Wang, JA., Eton, D., Webster, K. A. & Yu, H., Oct 1 2011, In : Journal of Cellular and Molecular Medicine. 15, 10, p. 2046-2056 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Defects in mitochondrial localization and ATP synthesis in the mdx mouse model of duchenne muscular dystrophy are not alleviated by PDE5 inhibition

Percival, J. M., Siegel, M. P., Knowels, G. & Marcinek, D. J., Jan 1 2013, In : Human molecular genetics. 22, 1, p. 153-167 15 p., dds415.

Research output: Contribution to journalArticle

64 Scopus citations

Defining disease, diagnosis, and translational medicine within a homeostatic perturbation paradigm: The National Institutes of Health undiagnosed diseases program experience

Gall, T., Valkanas, E., Bello, C., Markello, T., Adams, C., Bone, W. P., Brandt, A. J., Brazill, J. M., Carmichael, L., Davids, M., Davis, J., Diaz-Perez, Z., Draper, D., Elson, J., Flynn, E. D., Godfrey, R., Groden, C., Hsieh, C. K., Fischer, R., Golas, G. A. & 31 others, Guzman, J., Huang, Y., Kane, M. S., Lee, E., Li, C., Links, A. E., Maduro, V., Malicdan, M. C. V., Malik, F. S., Nehrebecky, M., Park, J., Pemberton, P., Schaffer, K., Simeonov, D., Sincan, M., Smedley, D., Valivullah, Z., Wahl, C., Washington, N., Wolfe, L. A., Xu, K., Zhu, Y., Gahl, W. A., Tifft, C. J., Toro, C., Adams, D. R., He, M., Robinson, P. N., Haendel, M. A., Zhai, R. G. & Boerkoel, C. F., Jan 1 2017, In : Frontiers in Medicine. 4, MAY, 62.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: A new intracellular target for matrix metalloproteinase-2

Sawicki, G., Leon, H., Sawicka, J., Sariahmetoglu, M., Schulze, C. J., Scott, P. G., Szczesna-Cordary, D. & Schulz, R., Jul 26 2005, In : Circulation. 112, 4, p. 544-552 9 p.

Research output: Contribution to journalArticle

206 Scopus citations

Deletion of 1-43 amino acids in cardiac myosin essential light chain blunts length dependency of ca2+ sensitivity and cross-bridge detachment kinetics

Michael, J. J., Gollapudi, S. K., Ford, S. J., Kazmierczak, K., Szczesna-Cordary, D. & Chandra, M., Jan 15 2013, In : American Journal of Physiology - Heart and Circulatory Physiology. 304, 2, p. H253-H259

Research output: Contribution to journalArticle

16 Scopus citations

Deletion of the first 45 NH2-terminal residues of rabbit skeletal troponin T strengthens binding of troponin to immobilized tropomyosin

Pan, B. S., Gordon, A. M. & Potter, J. D., Sep 23 1991, In : Journal of Biological Chemistry. 266, 19, p. 12432-12438 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21CIP1 levels in androgen-independent human prostate cancer cells

Knight-Krajewski, S., Welsh, C. F., Liu, Y., Lyons, L. S., Faysal, J. M., Yang, E. S. & Burnstein, K. L., Jul 15 2004, In : Oncogene. 23, 32, p. 5513-5522 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Design, synthesis, and evaluation of novel immunomodulatory small molecules targeting the CD40–CD154 costimulatory protein-protein interaction

Bojadzic, D., Chen, J., Alcazar, O. & Buchwald, P., Jan 1 2018, In : Molecules. 23, 5, 1153.

Research output: Contribution to journalArticle

3 Scopus citations
25 Scopus citations

Detection of two classes of Ca2+ binding sites in troponin C with circular dichroism and tyrosine fluorescence.

Johnson, J. D. & Potter, J. D., Jun 10 1978, In : Journal of Biological Chemistry. 253, 11, p. 3775-3777 3 p.

Research output: Contribution to journalArticle

68 Scopus citations

Determinants of agonist binding affinity on neuronal nicotinic receptor β subunits

Parker, M. J., Harvey, S. C. & Luetje, C. W., Oct 9 2001, In : Journal of Pharmacology and Experimental Therapeutics. 299, 1, p. 385-391 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Determinants of competitive antagonist sensitivity on neuronal nicotinic receptor β subunits

Harvey, S. C. & Luetje, C. W., Jan 1 1996, In : Journal of Neuroscience. 16, 12, p. 3798-3806 9 p.

Research output: Contribution to journalArticle

Open Access
142 Scopus citations

Determinants of Potency on α-Conotoxin MII, a Peptide Antagonist of Neuronal Nicotinic Receptors

Everhart, D., Cartier, G. E., Malhotra, A., Gomes, A. V., McIntosh, J. M. & Luetje, C. W., Mar 16 2004, In : Biochemistry. 43, 10, p. 2732-2737 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Determinants of specificity for α-conotoxin MII on α3β2 neuronal nicotinic receptors

Harvey, S. C., Mcintosh, J. M., Cartier, G. E., Maddox, F. N. & Luetje, C. W., Feb 1997, In : Molecular Pharmacology. 51, 2, p. 336-342 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Determinants of zinc potentiation on the α4 subunit of neuronal nicotinic receptors

Hsiao, B., Mihalak, K. B., Repicky, S. E., Everhart, D., Mederos, A. H., Malhotra, A. & Luetje, C. W., Jan 1 2006, In : Molecular Pharmacology. 69, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Determinants of α-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor β subunit

Shiembob, D. L., Roberts, R. L., Luetje, C. W. & McIntosh, J. M., Sep 19 2006, In : Biochemistry. 45, 37, p. 11200-11207 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Determination of the amino acid sequence of troponin C from rabbit skeletal muscle

Collins, J. H., Greaser, M. L., Potter, J. D. & Horn, M. J., Jan 1 1977, In : Journal of Biological Chemistry. 252, 18, p. 6356-6362 7 p.

Research output: Contribution to journalArticle

135 Scopus citations

Determination of the Ca2+ and Mg2+ affinity constants of troponin C from eel skeletal muscle and positioning of the single tryptophan in the primary structure

François, J. M., Gerday, C., Prendergast, F. G. & Potter, J. D., Dec 1 1993, In : Journal of Muscle Research and Cell Motility. 14, 6, p. 585-593 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Developing a data sharing community for spinal cord injury research

Callahan, A., Anderson, K. D., Beattie, M. S., Bixby, J. L., Ferguson, A. R., Fouad, K., Jakeman, L. B., Nielson, J. L., Popovich, P. G., Schwab, J. M. & Lemmon, V. P., Sep 2017, In : Experimental neurology. 295, p. 135-143 9 p.

Research output: Contribution to journalReview article

17 Scopus citations

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop

Jagodnik, K. M., Koplev, S., Jenkins, S. L., Ohno-Machado, L., Paten, B., Schurer, S. C., Dumontier, M., Verborgh, R., Bui, A., Ping, P., McKenna, N. J., Madduri, R., Pillai, A. & Ma'ayan, A., Jul 2017, In : Journal of biomedical informatics. 71, p. 49-57 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Development of a mouse model of menopausal ovarian cancer

Smith, E. R., Wang, Y. & Xu, X. X., Jan 1 2014, In : Frontiers in Oncology. 4 MAR, Article 36.

Research output: Contribution to journalReview article

10 Scopus citations

Development of compensatory thermogenesis in response to overfeeding in hypothyroid rats

Curcio, C., Lopes, A. M., Ribeiro, M. O., Francoso, O. A., Carvalho, S. D., Lima, F. B., Bicudo, J. E. & Bianco, A. C., Jan 1 1999, In : Endocrinology. 140, 8, p. 3438-3443 6 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties

Bibian, M., Rahaim, R. J., Choi, J. Y., Noguchi, Y., Schürer, S., Chen, W., Nakanishi, S., Licht, K., Rosenberg, L. H., Li, L., Feng, Y., Cameron, M. D., Duckett, D. R., Cleveland, J. L. & Roush, W. R., Aug 1 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 15, p. 4374-4380 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice

Abraham, T. P., Jones, M., Kazmierczak, K., Liang, H. Y., Pinheiro, A. C., Wagg, C. S., Lopaschuk, G. D. & Szczesna-Cordary, D., Apr 1 2009, In : Cardiovascular Research. 82, 1, p. 84-92 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Differences in the glucocorticoid to the progesterone receptor selectivity of inhaled glucocorticoids

Issar, M., Sahasranaman, S., Buchwald, P. & Hochhaus, G., Mar 1 2006, In : European Respiratory Journal. 27, 3, p. 511-516 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Different Functional Properties of Troponin T Mutants that Cause Dilated Cardiomyopathy

Venkatraman, G., Harada, K., Gomes, A. V., Kerrick, W. G. L. & Potter, J. D., Oct 24 2003, In : Journal of Biological Chemistry. 278, 43, p. 41670-41676 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
13 Scopus citations

Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation

Zhang, F., Saha, S., Shabalina, S. A. & Kashina, A., Sep 17 2010, In : Science. 329, 5998, p. 1534-1537 4 p.

Research output: Contribution to journalArticle

121 Scopus citations

Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts - Role of myofilament Ca2+ sensitivity increase

Sirenko, S. G., Potter, J. D. & Knollmann, B. C., Aug 1 2006, In : Journal of Physiology. 575, 1, p. 201-213 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release

Karpinsky-Semper, D., Volmar, C. H., Brothers, S. P. & Slepak, V. Z., May 2014, In : Molecular Pharmacology. 85, 5, p. 758-768 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Differential inhibition by α-conotoxin-MII of the nicotinic stimulation of [3H] dopamine release from rat striatal synaptosomes and slices

Kaiser, S. A., Soliakov, L., Harvey, S. C., Luetje, C. W. & Wonnacott, S., Mar 1 1998, In : Journal of neurochemistry. 70, 3, p. 1069-1076 8 p.

Research output: Contribution to journalArticle

139 Scopus citations

Differential regulation of synaptic vesicle protein genes by target and synaptic activity

Plunkett, J. A., Baccus, S. A. & Bixby, J. L., Aug 1 1998, In : Journal of Neuroscience. 18, 15, p. 5832-5838 7 p.

Research output: Contribution to journalArticle

18 Scopus citations