Molecular and Cellular Pharmacology

Research Output

A novel mouse model of in-stent restenosis

Rodriguez-Menocal, L., Wei, Y., Pham, S. M., St-Pierre, M., Li, S., Webster, K., Goldschmidt-Clermont, P. & Vazquez-Padron, R. I., Apr 1 2010, In : Atherosclerosis. 209, 2, p. 359-366 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

A novel nuclear role for the Vav3 nucleotide exchange factor in androgen receptor coactivation in prostate cancer

Rao, S., Lyons, L. S., Fahrenholtz, C. D., Wu, F., Farooq, A., Balkan, W. & Burnstein, K. L., Feb 1 2012, In : Oncogene. 31, 6, p. 716-727 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

A novel RING-finger-like protein Ini1 is essential for cell cycle progression in fission yeast

Oltra, E., Verde, F., Werner, R. & D'Urso, G., Feb 29 2004, In : Journal of Cell Science. 117, 6, p. 967-974 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth

Chen, B. & Bixby, J. L., Feb 26 2005, In : Journal of Neuroscience. 25, 4, p. 880-888 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

An overview of the challenges in designing, integrating, and delivering BARD: A public chemical-biology resource and query portal for multiple organizations, locations, and disciplines

De Souza, A., Bittker, J. A., Lahr, D. L., Brudz, S., Chatwin, S., Oprea, T. I., Waller, A., Yang, J. J., Southall, N., Guha, R., Schürer, S. C., Vempati, U. D., Southern, M. R., Dawson, E. S., Clemons, P. A. & Chung, T. D. Y., Jun 2014, In : Journal of Biomolecular Screening. 19, 5, p. 614-627 14 p.

Research output: Contribution to journalReview article

19 Scopus citations

Anoxia, acidosis, and intergenic interactions selectively regulate methionine sulfoxide reductase transcriptions in mouse embryonic stem cells

Zhang, C., Jia, P., Jia, Y., Li, Y., Webster, K. A., Huang, X., Achary, M., Lemanski, S. L. & Lemanski, L. F., Jan 1 2011, In : Journal of cellular biochemistry. 112, 1, p. 98-106 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells

Kizu, R., Okamura, K., Toriba, A., Mizokami, A., Burnstein, K. L., Klinge, C. M. & Hayakawa, K., Dec 1 2003, In : Toxicological Sciences. 76, 2, p. 299-309 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Antiandrogenic activity of extracts of diesel exhaust particles emitted from diesel-engine truck under different engine loads and speeds

Okamura, K., Kizu, R., Toriba, A., Murahashi, T., Mizokami, A., Burnstein, K. L., Klinge, C. M. & Hayakawa, K., Feb 15 2004, In : Toxicology. 195, 2-3, p. 243-254 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Antibodies and antibody-fusion proteins as anti-angiogenic, anti-tumor agents

Calfa, C. I., Rosenblatt, J. D., Cho, H. M., Webster, K. & Shin, S. U., Jun 1 2006, In : Update on Cancer Therapeutics. 1, 2, p. 159-173 15 p.

Research output: Contribution to journalReview article

6 Scopus citations

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

Choi, J. H., Banks, A. S., Kamenecka, T. M., Busby, S. A., Chalmers, M. J., Kumar, N., Kuruvilla, D. S., Shin, Y., He, Y., Bruning, J. B., Marciano, D. P., Cameron, M. D., Laznik, D., Jurczak, M. J., Schürer, S. C., Vidović, D., Shulman, G. I., Spiegelman, B. M. & Griffin, P. R., Sep 22 2011, In : Nature. 477, 7365, p. 477-481 5 p.

Research output: Contribution to journalArticle

330 Scopus citations
213 Scopus citations

Aphid amino acid transporter regulates glutamine supply to intracellular bacterial symbionts

Price, D. R. G., Feng, H., Baker, J. D., Bavan, S., Luetje, C. W. & Wilson, A. C. C., Jan 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1, p. 320-325 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

Apoptosis Inhibitors for Heart Disease

Webster, K. A. & Bishopric, N. H., Dec 16 2003, In : Circulation. 108, 24, p. 2954-2956 3 p.

Research output: Contribution to journalReview article

14 Scopus citations

Apoptosis-like yeast cell death in response to DNA damage and replication defects

Burhans, W. C., Weinberger, M., Marchetti, M. A., Ramachandran, L., D'Urso, G. & Huberman, J. A., Nov 27 2003, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 532, 1-2, p. 227-243 17 p.

Research output: Contribution to journalReview article

88 Scopus citations
24 Scopus citations
16 Scopus citations

Appointing a proxy under the best of circumstances.

White, P. D., Dec 1 1992, In : Utah law review. 1992, 3, p. 849-860 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

A Protocol for Characterizing the Impact of Collateral Flow after Distal Middle Cerebral Artery Occlusion

DeFazio, R. A., Levy, S., Morales, C. L., Levy, R. V., Lin, H. W., Abaffy, T., Dave, K. R., Watson, B. D., Perez-Pinzon, M. A. & Ohanna, V., Mar 1 2011, In : Translational stroke research. 2, 1, p. 112-127 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

A Rapid and Precise Mutation-Activated Fluorescence Reporter for Analyzing Acute Mutagenesis Frequency

Birnbaum, M. D., Nemzow, L., Kumar, A., Gong, F. & Zhang, F., Jan 1 2018, (Accepted/In press) In : Cell Chemical Biology.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

A redução do ventrículo esquerdo não apenas diminui a pós-carga

Translated title of the contribution: Left ventricular reduction does not reduce only the after loadTucci, P. J. F. & Kanashiro, R. M., Apr 4 2004, In : Arquivos Brasileiros de Cardiologia. 82, 3, p. 209-211 3 p.

Research output: Contribution to journalEditorial

A Reliable Mouse Model of Hind limb Gangrene

Parikh, P. P., Castilla, D., Soares, R., Shao, H., Regueiro, M., Li, Y., Vazquez-Padron, R. I., Webster, K. A., Liu, Z-J. & Velazquez, O. C., Jan 1 2017, (Accepted/In press) In : Annals of Vascular Surgery.

Research output: Contribution to journalArticle

1 Scopus citations

Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer

Zhao, N., Peacock, S. O., Lo, C. H., Heidman, L. M., Rice, M. A., Fahrenholtz, C. D., Greene, A. M., Magani, F., Copello, V. A., Martinez, M. J., Zhang, Y., Daaka, Y., Lynch, C. C. & Burnstein, K. L., Jan 1 2019, In : Science Translational Medicine. 11, 498, eaaw4636.

Research output: Contribution to journalArticle

2 Scopus citations

Arginylation-dependent neural crest cell migration is essential for mouse development

Kurosaka, S., Leu, N. A., Zhang, F., Bunte, R., Saha, S., Wang, J., Guo, C., He, W. & Kashina, A., Mar 1 2010, In : PLoS genetics. 6, 3, e1000878.

Research output: Contribution to journalArticle

42 Scopus citations

Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion

Zhang, F., Saha, S. & Kashina, A., Jun 11 2012, In : Journal of Cell Biology. 197, 6, p. 819-836 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

Arginylation regulates intracellular actin polymer level by modulating actin properties and binding of capping and severing proteins

Saha, S., Mundia, M. M., Zhang, F., Demers, R. W., Korobova, F., Svitkina, T., Perieteanu, A. A., Dawson, J. F. & Kashina, A., Apr 15 2010, In : Molecular biology of the cell. 21, 8, p. 1350-1361 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase

Zhang, F., Patel, D. M., Colavita, K., Rodionova, I., Buckley, B., Scott, D. A., Kumar, A., Shabalina, S. A., Saha, S., Chernov, M., Osterman, A. L. & Kashina, A., Jul 15 2015, In : Nature Communications. 6, 8517.

Research output: Contribution to journalArticle

18 Scopus citations

Arginyltransferase is an ATP-independent self-regulating enzyme that forms distinct functional complexes in vivo

Wang, J., Han, X., Saha, S., Xu, T., Rai, R., Zhang, F., Wolf, Y. I., Wolfson, A., Yates, J. R. & Kashina, A., Jan 28 2011, In : Chemistry and Biology. 18, 1, p. 121-130 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers

Rai, R., Zhang, F., Colavita, K., Leu, N. A., Kurosaka, S., Kumar, A., Birnbaum, M. D., Győrffy, B., Dong, D. W., Shtutman, M. & Kashina, A., Dec 21 2015, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

9 Scopus citations

A role of aryl hydrocarbon receptor in the antiandrogenic effects of polycyclic aromatic hydrocarbons in LNCaP human prostate carcinoma cells

Kizu, R., Okamura, K., Toriba, A., Kakishima, H., Mizokami, A., Burnstein, K. L. & Hayakawa, K., Jun 1 2003, In : Archives of Toxicology. 77, 6, p. 335-343 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

A routine electrocardiogram should not be used to determine the size of myocardial infarction in the rat

Bonilha, A. M. M., Saraiva, R. M., Kanashiro, R. M., Portes, L. A., Antonio, E. L. & Tucci, P. J. F., Apr 2005, In : Brazilian Journal of Medical and Biological Research. 38, 4, p. 615-619 5 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their Activity

Hanson, S. M., Cleghorn, W. M., Francis, D. J., Vishnivetskiy, S. A., Raman, D., Song, X., Nair, K. S., Slepak, V. Z., Klug, C. S. & Gurevich, V. V., Apr 27 2007, In : Journal of molecular biology. 368, 2, p. 375-387 13 p.

Research output: Contribution to journalArticle

83 Scopus citations

A simple, predictive, structure-based skin permeability model

Buchwald, P. & Bodor, N., Aug 29 2001, In : Journal of Pharmacy and Pharmacology. 53, 8, p. 1087-1098 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

A sirtuin link between metabolism and heart disease

Webster, K. A., Nov 1 2012, In : Nature medicine. 18, 11, p. 1617-1619 3 p.

Research output: Contribution to journalShort survey

9 Scopus citations

Aspectos estruturais e funcionais do coração de ratos com e sem infarto do miocárdio. Experiência inicial com ecocardiografia doppler

Moisés, V. A., Ferreira, R. L., Nozawa, E., Kanashiro, R. M., Campos, O., De Andrade, J. L., Carvalho, A. C. C. & Tucci, P. J. F., Dec 1 2000, In : Arquivos Brasileiros de Cardiologia. 75, 2, p. 125-130 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

A sphingosine 1-phosphate receptor 2 selective allosteric agonist

Satsu, H., Schaeffer, M. T., Guerrero, M., Saldana, A., Eberhart, C., Hodder, P., Cayanan, C., Schürer, S., Bhhatarai, B., Roberts, E., Rosen, H. & Brown, S. J., Sep 1 2013, In : Bioorganic and Medicinal Chemistry. 21, 17, p. 5373-5382 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Assaying locomotor, learning, and memory deficits in Drosophila models of neurodegeneration

Ali, Y. O., Escala, W., Ruan, K. & Zhai, R. G., Mar 2011, In : Journal of Visualized Experiments. 49, e2504.

Research output: Contribution to journalArticle

77 Scopus citations

Assembling the presynaptic active zone: A characterization of an active zone precursor vesicle

Zhai, R. G., Vardinon-Friedman, H., Cases-Langhoff, C., Becker, B., Gundelfinger, E. D., Ziv, N. E. & Garner, C. C., Jan 1 2001, In : Neuron. 29, 1, p. 131-143 13 p.

Research output: Contribution to journalArticle

324 Scopus citations

Assignment of an oligomycin-resistance locus to human chromosome 10

Webster, K. A., Oliver, N. A. & Wallace, D. C., Mar 1 1982, In : Somatic Cell Genetics. 8, 2, p. 223-244 22 p.

Research output: Contribution to journalArticle

12 Scopus citations
22 Scopus citations
123 Scopus citations

Atg27 tyrosine sorting motif is important for its trafficking and Atg9 localization

Segarra, V. A., Boettner, D. R. & Lemmon, S., Apr 1 2015, In : Traffic. 16, 4, p. 365-378 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
6 Scopus citations

A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin

Pinto, J. R., Parvatiyar, M. S., Jones, M. A., Liang, J. & Potter, J. D., Jan 25 2008, In : Journal of Biological Chemistry. 283, 4, p. 2156-2166 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Attempts of ranking in a series of synthetic nonpsychotropic cannabinoids

Pop, E. & Buchwald, P., Jan 1 2001, In : SAR and QSAR in environmental research. 12, 1-2, p. 113-127 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging

Ruetenik, A. L., Ocampo, A., Ruan, K., Zhu, Y., Li, C., Zhai, R. G. & Barrientos, A., Aug 1 2016, In : Microbial Cell. 3, 8, p. 338-351 14 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

At the cutting edge: The down side of glucocorticoid receptor regulation

Burnstein, K. L. & Cidlowski, J. A., Jan 1 1992, In : Molecular and Cellular Endocrinology. 83, 1, p. C1+C2+C3+C4+C5+C6+C7+C8+

Research output: Contribution to journalReview article

77 Scopus citations

A unique pathway of cardiac myocyte death caused by hypoxia-acidosis

Graham, R. M., Frazier, D. P., Thompson, J. W., Haliko, S., Li, H., Wasserlauf, B. J., Spiga, M. G., Bishopric, N. H. & Webster, K. A., Aug 1 2004, In : Journal of Experimental Biology. 207, 18, p. 3189-3200 12 p.

Research output: Contribution to journalReview article

135 Scopus citations

Autophosphorylation and ADP regulate the Ca2+-dependent interaction of recoverin with rhodopsin kinase

Satpaev, D. K., Chen, C. K., Scotti, A., Simon, M. I., Hurley, J. B. & Slepak, V. Z., Jul 14 1998, In : Biochemistry. 37, 28, p. 10256-10262 7 p.

Research output: Contribution to journalArticle

22 Scopus citations