Molecular and Cellular Pharmacology

Research Output

2009

Dimerization of tyrosine phosphatase PTPRO decreases its activity and ability to inactivate TrkC

Hower, A. E., Beltran, P. J. & Bixby, J. L., Sep 1 2009, In : Journal of neurochemistry. 110, 5, p. 1635-1647 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

Endothelin-1 enhances the expression of the androgen receptor via activation of the c-myc pathway in prostate cancer cells

Lee, J. G., Zheng, R., McCafferty-Cepero, J. M., Burnstein, K. L., Nanus, D. M. & Shen, R., Feb 1 2009, In : Molecular Carcinogenesis. 48, 2, p. 141-149 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Extracellular calcium increases CXCR4 expression on bone marrow-derived cells and enhances pro-angiogenesis therapy

Wu, Q., Shao, H., Darwin Eton, D., Li, J., Li, J., Yang, B., Webster, K. A. & Yu, H., Sep 1 2009, In : Journal of Cellular and Molecular Medicine. 13, 9 B, p. 3764-3773 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
76 Scopus citations

Fluorescence lifetime of actin in the familial hypertrophic cardiomyopathy transgenic heart

Mettikolla, P., Luchowski, R., Gryczynski, I., Gryczynski, Z., Szczesna-Cordary, D. & Borejdo, J., Feb 17 2009, In : Biochemistry. 48, 6, p. 1264-1271 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Functional Effects of a Restrictive-Cardiomyopathy-Linked Cardiac Troponin I Mutation (R145W) in Transgenic Mice

Wen, Y., Xu, Y., Wang, Y., Pinto, J. R., Potter, J. D. & Kerrick, W. G. L., Oct 9 2009, In : Journal of molecular biology. 392, 5, p. 1158-1167 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Identification of novel agonists of the integrin CD11b/CD18

Faridi, M. H., Maiguel, D., Barth, C. J., Stoub, D., Day, R., Schürer, S. & Gupta, V., Dec 15 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 24, p. 6902-6906 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Inhibition of androgen receptor transcriptional activity as a novel mechanism of action of arsenic

Rosenblatt, A. E. & Burnstein, K. L., Mar 1 2009, In : Molecular Endocrinology. 23, 3, p. 412-421 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

In vivo upregulation of nitric oxide synthases in healthy rats

Wu, H., Jin, Y., Arias, J., Bassuk, J., Uryash, A., Kurlansky, P., Webster, K. & Adams, J. A., Aug 1 2009, In : Nitric Oxide - Biology and Chemistry. 21, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

KLF family members regulate intrinsic axon regeneration ability

Moore, D. L., Blackmore, M. G., Hu, Y., Kaestner, K. H., Bixby, J. L., Lemmon, V. P. & Goldberg, J. L., Oct 9 2009, In : Science. 326, 5950, p. 298-301 4 p.

Research output: Contribution to journalArticle

397 Scopus citations
11 Scopus citations
48 Scopus citations
7 Scopus citations

Molecular receptive range variation among mouse odorant receptors for aliphatic carboxylic acids

Repicky, S. E. & Luetje, C. W., Apr 1 2009, In : Journal of neurochemistry. 109, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme

Zhai, R. G., Rizzi, M. & Garavaglia, S., Sep 1 2009, In : Cellular and Molecular Life Sciences. 66, 17, p. 2805-2818 14 p.

Research output: Contribution to journalReview article

49 Scopus citations

Patterning and organization of motor neuron dendrites in the Drosophila larva

Kim, M. D., Wen, Y. & Jan, Y. N., Dec 15 2009, In : Developmental Biology. 336, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Phosphatidic acid potentiates Gαq stimulation of phospholipase C-β1 signaling

Litosch, I., Dec 18 2009, In : Biochemical and biophysical research communications. 390, 3, p. 603-607 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Phosphatidic acid regulates signal output by G protein coupled receptors through direct interaction with phospholipase C-β1

Litosch, I., Pujari, R. & Lee, S. J., Sep 1 2009, In : Cellular Signalling. 21, 9, p. 1379-1384 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Protein tyrosine phosphatase receptor type O regulates development and function of the sensory nervous system

Gonzalez-Brito, M. R. & Bixby, J. L., Nov 1 2009, In : Molecular and Cellular Neuroscience. 42, 4, p. 458-465 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Quantitative assessment of islet cell products: Estimating the accuracy of the existing protocol and accounting for islet size distribution

Buchwald, P., Wang, X., Khan, A., Bernal, A., Fraker, C., Inverardi, L. & Ricordi, C., Dec 1 2009, In : Cell Transplantation. 18, 10-11, p. 1223-1235 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics

Greenberg, M. J., Watt, J. D., Jones, M., Kazmierczak, K., Szczesna-Cordary, D. & Moore, J. R., Jan 1 2009, In : Journal of Molecular and Cellular Cardiology. 46, 1, p. 108-115 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Removal of the cardiac myosin regulatory light chain increases isometric force production

Pant, K., Watt, J., Greenberg, M., Jones, M., Szczesna-Cordary, D. & Moore, J. R., Oct 1 2009, In : FASEB Journal. 23, 10, p. 3571-3580 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Sex-specific impact of aldosterone receptor antagonism on ventricular remodeling and gene expression after myocardial infarction

Kanashiro-Takeuchi, R. M., Heidecker, B., Lamirault, G., Dharamsi, J. W. & Hare, J. M., Jan 1 2009, In : Clinical and Translational Science. 2, 2, p. 134-142 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Small-molecule costimulatory blockade: Organic dye inhibitors of the CD40-CD154 interaction

Margolles-Clark, E., Umland, O., Kenyon, N. S., Ricordi, C. & Buchwald, P., Nov 1 2009, In : Journal of Molecular Medicine. 87, 11, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Suramin inhibits the CD40-CD154 costimulatory interaction: A possible mechanism for immunosuppressive effects

Margolles-Clark, E., Jacques-Silva, M. C., Ganesan, L., Umland, O., Kenyon, N. S., Ricordi, C., Berggren, P. O. & Buchwald, P., Apr 1 2009, In : Biochemical Pharmacology. 77, 7, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Teach, then trust Elizabeth W. Jones (1939-2008): mentor to many.

Connelly, T. D., Lemmon, S. K., Mitchell, A. P. & Woolford, J., Feb 2009, In : Genetics. 181, 2, p. 357-365 9 p.

Research output: Contribution to journalArticle

The Conserved NDR Kinase Orb6 Controls Polarized Cell Growth by Spatial Regulation of the Small GTPase Cdc42

Das, M., Wiley, D. J., Chen, X., Shah, K. & Verde, F., Aug 11 2009, In : Current Biology. 19, 15, p. 1314-1319 6 p.

Research output: Contribution to journalArticle

55 Scopus citations

The F-BAR Protein Syp1 Negatively Regulates WASp-Arp2/3 Complex Activity during Endocytic Patch Formation

Boettner, D. R., D'Agostino, J. L., Torres, O. T., Daugherty-Clarke, K., Uygur, A., Reider, A., Wendland, B., Lemmon, S. K. & Goode, B. L., Dec 15 2009, In : Current Biology. 19, 23, p. 1979-1987 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism

Bianco, S. D. C. & Kaiser, U. B., Oct 1 2009, In : Nature Reviews Endocrinology. 5, 10, p. 569-576 8 p.

Research output: Contribution to journalReview article

169 Scopus citations
35 Scopus citations

The molecular effects of skeletal muscle myosin regulatory light chain phosphorylation

Greenberg, M. J., Mealy, T. R., Watt, J. D., Jones, M., Szczesna-Cordary, D. & Moore, J. R., Aug 1 2009, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 297, 2, p. R265-R274

Research output: Contribution to journalArticle

48 Scopus citations

The Role of the N-Terminus of the Myosin Essential Light Chain in Cardiac Muscle Contraction

Kazmierczak, K., Xu, Y., Jones, M., Guzman, G., Hernandez, O. M., Kerrick, W. G. L. & Szczesna-Cordary, D., Apr 3 2009, In : Journal of molecular biology. 387, 3, p. 706-725 20 p.

Research output: Contribution to journalArticle

40 Scopus citations
2008

Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation

Yin, L., Locovei, A. M. & D'Urso, G., Oct 1 2008, In : Molecular biology of the cell. 19, 10, p. 4374-4382 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

A Myc-slug (Snail 2)/Twist regulatory circuit directs vascular development

Rodrigues, C. O., Nerlick, S. T., White, E. L., Cleveland, J. L. & King, M. L., Jun 1 2008, In : Development. 135, 11, p. 1903-1911 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

A new in vitro model of the glial scar inhibits axon growth

Wanner, I. B., Deik, A., Torres, M., Rosendahl, A., Neary, J. T., Lemmon, V. P. & Bixby, J. L., Dec 1 2008, In : Glia. 56, 15, p. 1691-1709 19 p.

Research output: Contribution to journalArticle

103 Scopus citations

A novel angiographic methodology for the quantification of angiogenesis

Gounis, M. J., Lieber, B. B., Webster, K. A. & Wakhloo, A. K., Mar 1 2008, In : IEEE Transactions on Biomedical Engineering. 55, 3, p. 996-1003 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin

Pinto, J. R., Parvatiyar, M. S., Jones, M. A., Liang, J. & Potter, J. D., Jan 25 2008, In : Journal of Biological Chemistry. 283, 4, p. 2156-2166 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Bot1p is required for mitochondrial translation, respiratory function, and normal cell morphology in the fission yeast Schizosaccharomyces pombe

Wiley, D. J., Catanuto, P., Fontanesi, F., Rios, C., Sanchez, N., Barrientos, A. & Verde, F., Apr 1 2008, In : Eukaryotic Cell. 7, 4, p. 619-629 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Brief report: A GPR54-activating mutation in a patient with central precocious puberty

Teles, M. G., Bianco, S. D. C., Brito, V. N., Trarbach, E. B., Kuohung, W., Xu, S., Seminara, S. B., Mendonca, B. B., Kaiser, U. B. & Latronico, A. C., Feb 14 2008, In : New England Journal of Medicine. 358, 7, p. 709-715 7 p.

Research output: Contribution to journalArticle

347 Scopus citations

Cardiac troponin T forms a tetramer in vitro

Lounes, K. C., Demeler, B., Anderson, D. E., Gomes, A. W., Potter, J. D., Nassar, R. & Anderson, P. A. W., Feb 19 2008, In : Biochemistry. 47, 7, p. 1970-1976 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
34 Scopus citations

EST express: PHP/MySQL based automated annotation of ESTs from expression libraries

Smith, R. P., Buchser, W. J., Lemmon, M. B., Pardinas, J. R., Bixby, J. L. & Lemmon, V. P., Apr 10 2008, In : BMC Bioinformatics. 9, 186.

Research output: Contribution to journalArticle

3 Scopus citations

Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice

Wen, Y., Pinto, J. R., Gomes, A. V., Xu, Y., Wang, Y., Wang, Y., Potter, J. D. & Kerrick, W. G. L., Jul 18 2008, In : Journal of Biological Chemistry. 283, 29, p. 20484-20494 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

Buchwald, P., Feb 1 2008, In : Steroids. 73, 2, p. 193-208 16 p.

Research output: Contribution to journalArticle

31 Scopus citations

High-throughput screening for human galactokinase inhibitors

Wierenga, K. J., Lai, K., Buchwald, P. & Tang, M., Aug 1 2008, In : Journal of Biomolecular Screening. 13, 5, p. 415-423 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

In vivo labeling and analysis of mitochondrial translation products in budding and in fission yeasts

Gouget, K., Verde, F. & Barrientos, A., Dec 1 2008, Methods in Molecular Biology. Vol. 457. p. 113-124 12 p. (Methods in Molecular Biology; vol. 457).

Research output: Chapter in Book/Report/Conference proceedingChapter

In vivo labeling and analysis of mitochondrial translation products in budding and in fission yeasts

Gouget, K., Verde, F. & Barrientos, A., 2008, Methods in Molecular Biology. Humana Press Inc., Vol. 457. p. 113-124 12 p. (Methods in Molecular Biology; vol. 457).

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

Ligand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancer

Lyons, L. S., Rao, S., Balkan, W., Faysal, J., Maiorino, C. A. & Burnstein, K. L., Mar 1 2008, In : Molecular Endocrinology. 22, 3, p. 597-608 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Mechanism of light-induced translocation of arrestin and transducin in photoreceptors: Interaction-restricted diffusion

Slepak, V. Z. & Hurley, J. B., Dec 1 2008, In : IUBMB life. 60, 1, p. 2-9 8 p.

Research output: Contribution to journalReview article

51 Scopus citations

Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C

Landstrom, A. P., Parvatiyar, M. S., Pinto, J. R., Marquardt, M. L., Bos, J. M., Tester, D. J., Ommen, S. R., Potter, J. D. & Ackerman, M. J., Aug 1 2008, In : Journal of Molecular and Cellular Cardiology. 45, 2, p. 281-288 8 p.

Research output: Contribution to journalArticle

76 Scopus citations