Molecular and Cellular Pharmacology

Research Output 1974 2019

2018
2 Citations (Scopus)
Spectrin
Sarcolemma
Nitric Oxide Synthase Type I
Dystrophin
Duchenne Muscular Dystrophy
4 Citations (Scopus)

Phosphomimetic-mediated in vitro rescue of hypertrophic cardiomyopathy linked to R58Q mutation in myosin regulatory light chain

Yadav, S., Kazmierczak, K., Liang, J., Sitbon, Y. H. & Szczesna-Cordary, D., Jan 1 2018, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Myosin Light Chains
Hypertrophic Cardiomyopathy
Myosins
Phosphorylation
Muscle
7 Citations (Scopus)

Polypharmacology or promiscuity? Structural interactions of resveratrol with its bandwagon of targets

Saqib, U., Kelley, T. T., Panguluri, S. K., Liu, D., Savai, R., Baig, M. S. & Schuerer, S. C., Oct 24 2018, In : Frontiers in Pharmacology. 9, OCT, 1201.

Research output: Contribution to journalArticle

Polypharmacology
Proteins
Databases
Stilbenes
Vitis
2 Citations (Scopus)

Publisher Correction: Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Hervera, A., de Virgiliis, F., Palmisano, I., Zhou, L., Tantardini, E., Kong, G., Hutson, T., Danzi, M. C., Perry, R. B. T., Santos, C. X. C., Kapustin, A. N., Fleck, R. A., Del Río, J. A., Carroll, T., Lemmon, V., Bixby, J., Shah, A. M., Fainzilber, M. & Di Giovanni, S., Mar 8 2018, (Accepted/In press) In : Nature Cell Biology. 1 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Spain
Axons
Regeneration
Reactive Oxygen Species
1 Citation (Scopus)

Quantitative cell biology of neurodegeneration in drosophila through unbiased analysis of fluorescently tagged proteins using imageJ

Brazill, J. M., Zhu, Y., Li, C. & Zhai, R. G., Aug 3 2018, In : Journal of Visualized Experiments. 2018, 138, e58041.

Research output: Contribution to journalArticle

Cytology
Drosophila
Cell Biology
Optical Imaging
Autophagy
36 Citations (Scopus)

Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Hervera, A., De Virgiliis, F., Palmisano, I., Zhou, L., Tantardini, E., Kong, G., Hutson, T., Danzi, M. C., Perry, R. B. T., Santos, C. X. C., Kapustin, A. N., Fleck, R. A., Del Río, J. A., Carroll, T., Lemmon, V., Bixby, J., Shah, A. M., Fainzilber, M. & Di Giovanni, S., Mar 1 2018, In : Nature Cell Biology. 20, 3, p. 307-319 13 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Axons
Regeneration
Reactive Oxygen Species
Phosphatidylinositol 3-Kinases
1 Citation (Scopus)

Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis

Birnbaum, M. D., Zhao, N., Moorthy, B. T., Patel, D. M., Kryvenko, O. N., Heidman, L., Kumar, A., Morgan, W. M., Ban, Y., Reis, I. M., Chen, X., Gonzalgo, M. L., Jorda, M., Burnstein, K. L. & Zhang, F., Jan 1 2018, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

arginyltransferase
Prostatic Neoplasms
Neoplasm Metastasis
Cell Line
Phenotype
3 Citations (Scopus)

Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth

Donda, K., Zambrano, R., Moon, Y., Percival, J., Vaidya, R., Dapaah-Siakwan, F., Luo, S., Duncan, M. R., Bao, Y., Wang, L., Qin, L., Benny, M., Young, K. & Wu, S., Jul 1 2018, In : PLoS One. 13, 7, e0199927.

Research output: Contribution to journalArticle

hyperoxia
Hyperoxia
Bone Development
Lung Injury
Pulmonary Hypertension
6 Citations (Scopus)

Sarcomeric perturbations of myosin motors lead to dilated cardiomyopathy in genetically modified MYL2 mice

Yuan, C. C., Kazmierczak, K., Liang, J., Zhou, Z., Yadav, S., Gomes, A. V., Irving, T. C. & Szczesna-Cordary, D., Mar 6 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 10, p. E2338-E2347

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Myosins
Dilatation
Cardiac Myosins
Phenotype
3 Citations (Scopus)

Scaffold Ranking and Positional Scanning Identify Novel Neurite Outgrowth Promoters with Nanomolar Potency

Al-Ali, H., Debevec, G., Santos, R. G., Houghten, R. A., Davis, J. C., Nefzi, A., Lemmon, V., Bixby, J. & Giulianotti, M. A., Oct 11 2018, In : ACS Medicinal Chemistry Letters. 9, 10, p. 1057-1062 6 p.

Research output: Contribution to journalArticle

Neurology
Scaffolds
Axons
Neurons
Scanning
4 Citations (Scopus)

Secretogranin III: a diabetic retinopathy-selective angiogenic factor

Li, W., Webster, K. A., LeBlanc, M. E. & Tian, H., Feb 1 2018, In : Cellular and Molecular Life Sciences. 75, 4, p. 635-647 13 p.

Research output: Contribution to journalReview article

Angiogenesis Inducing Agents
Diabetic Retinopathy
Secretory Vesicles
Pathologic Neovascularization
Retinal Neovascularization
7 Citations (Scopus)

Single cardiac ventricular myosins are autonomous motors

Wang, Y., Yuan, C. C., Kazmierczak, K., Szczesna-Cordary, D. & Burghardt, T. P., Jan 1 2018, In : Open Biology. 4, 8, 170240.

Research output: Contribution to journalArticle

Cardiac Myosins
Ventricular Myosins
Myosins
Muscle
Actins
5 Citations (Scopus)

Sustainable data and metadata management at the BD2K-LINCS Data coordination and integration center

Stathias, V., Koleti, A., Vidovic, D., Cooper, D. J., Jagodnik, K. M., Terryn, R., Forlin, M., Chung, C., Torre, D., Ayad, N., Medvedovic, M., Ma'Ayan, A., Pillai, A. & Schuerer, S. C., Jun 19 2018, In : Scientific data. 5, 180117.

Research output: Contribution to journalArticle

Metadata
Information management
Data Management
Assays
management
3 Citations (Scopus)

The effect of Jun dimerization on neurite outgrowth and motif binding

Danzi, M. C., Mehta, S. T., Dulla, K., Zunino, G., Cooper, D. J., Bixby, J. & Lemmon, V., Oct 1 2018, In : Molecular and Cellular Neuroscience. 92, p. 114-127 14 p.

Research output: Contribution to journalArticle

Dimerization
Spinal Ganglia
Neurons
Axons
Axotomy
70 Citations (Scopus)

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., Kuleshov, M. V., Ma'ayan, A., Stathias, V., Terryn, R., Cooper, D., Forlin, M., Koleti, A., Vidovic, D., Chung, C., Schuerer, S. C. & 87 others, Vasiliauskas, J., Pilarczyk, M., Shamsaei, B., Fazel, M., Ren, Y., Niu, W., Clark, N. A., White, S., Mahi, N., Zhang, L., Kouril, M., Reichard, J. F., Sivaganesan, S., Medvedovic, M., Meller, J., Koch, R. J., Birtwistle, M. R., Iyengar, R., Sobie, E. A., Azeloglu, E. U., Kaye, J., Osterloh, J., Haston, K., Kalra, J., Finkbiener, S., Li, J., Milani, P., Adam, M., Escalante-Chong, R., Sachs, K., Lenail, A., Ramamoorthy, D., Fraenkel, E., Daigle, G., Hussain, U., Coye, A., Rothstein, J., Sareen, D., Ornelas, L., Banuelos, M., Mandefro, B., Ho, R., Svendsen, C. N., Lim, R. G., Stocksdale, J., Casale, M. S., Thompson, T. G., Wu, J., Thompson, L. M., Dardov, V., Venkatraman, V., Matlock, A., Van Eyk, J. E., Jaffe, J. D., Papanastasiou, M., Subramanian, A., Golub, T. R., Erickson, S. D., Fallahi-Sichani, M., Hafner, M., Gray, N. S., Lin, J. R., Mills, C. E., Muhlich, J. L., Niepel, M., Shamu, C. E., Williams, E. H., Wrobel, D., Sorger, P. K., Heiser, L. M., Gray, J. W., Korkola, J. E., Mills, G. B., LaBarge, M., Feiler, H. S., Dane, M. A., Bucher, E., Nederlof, M., Sudar, D., Gross, S., Kilburn, D. F., Smith, R., Devlin, K., Margolis, R., Derr, L., Lee, A. & Pillai, A., Jan 24 2018, In : Cell Systems. 6, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

Cataloging
Libraries
Inborn Genetic Diseases
Molecular Imaging
Neurodegenerative Diseases
9 Citations (Scopus)
Proteins
Immunomodulation
Biological Products
CD40 Ligand
Pharmaceutical Chemistry
45 Citations (Scopus)

Unexplored therapeutic opportunities in the human genome

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., Von Mering, C., Muthas, D., Nguyen, D. T., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schuerer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidović, D., Waller, A., Westergaard, D., Yang, J. J. & Zahoránszky-Köhalmi, G., Apr 27 2018, In : Nature Reviews Drug Discovery. 17, 5, p. 317-332 16 p.

Research output: Contribution to journalReview article

Human Genome
Biomedical Research
Proteins
G-Protein-Coupled Receptor Kinases
Genome
2017
9 Citations (Scopus)

Amino acid metabolites that regulate G protein signaling during osmotic stress

Shellhammer, J. P., Morin-Kensicki, E., Matson, J. P., Yin, G., Isom, D. G., Campbell, S. L., Mohney, R. P. & Dohlman, H. G., May 1 2017, In : PLoS Genetics. 13, 5, e1006829.

Research output: Contribution to journalArticle

Osmoregulation
Branched Chain Amino Acids
Osmotic Pressure
osmotic stress
G-proteins
1 Citation (Scopus)

A Reliable Mouse Model of Hind limb Gangrene

Parikh, P. P., Castilla, D., Soares, R., Shao, H., Regueiro, M., Li, Y., Vazquez-Padron, R. I., Webster, K. A., Liu, Z-J. & Velazquez, O. C., Jan 1 2017, (Accepted/In press) In : Annals of Vascular Surgery.

Research output: Contribution to journalArticle

Gangrene
Extremities
Femoral Artery
Ligation
NG-Nitroarginine Methyl Ester
6 Citations (Scopus)
Statistical Models
Signal Transduction
Ligands
2 Citations (Scopus)

Cardiac contractility, motor function, and cross-bridge kinetics in N47K-RLC mutant mice

Wang, L., Kazmierczak, K., Yuan, C. C., Yadav, S., Kawai, M. & Szczesna-Cordary, D., Jun 1 2017, In : FEBS Journal. 284, 12, p. 1897-1913 17 p.

Research output: Contribution to journalArticle

Myosins
pioglitazone
Light
Adenosine Diphosphate
Kinetics
4 Citations (Scopus)

Comprehensive metabolomics study to assess longitudinal biochemical changes and potential early biomarkers in nonobese diabetic mice that progress to diabetes

Buchwald, P., Tamayo-Garcia, A., Ramamoorthy, S., Garcia-Contreras, M., Mendez, A. J. & Ricordi, C., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3873-3890 18 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Metabolomics
Biomarkers
Medical problems
Type 1 Diabetes Mellitus

Correction: Emerging roles of the single EF-hand Ca2+ sensor tescalcin in the regulation of gene expression, cell growth and differentiation [J. Cell Sci, 129, (3533-3540)]

Kolobynina, K. G., Solovyova, V. V., Levay, K., Rizvanov, A. A. & Slepak, V. Z., 2017, In : Journal of Cell Science. 130, 2, p. 521 1 p.

Research output: Contribution to journalComment/debate

EF Hand Motifs
Gene Knockout Techniques
Gene Expression Regulation
Knockout Mice
Cell Differentiation

Correction: Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit (PLoS ONE (2017) 12:5 (e0177454) DOI: 10.1371/journal.pone.0177454)

Kepchia, D., Moliver, S., Chohan, K., Phillips, C. & Luetje, C. W., Aug 1 2017, In : PLoS One. 12, 8, e0183009.

Research output: Contribution to journalComment/debate

Odorant Receptors
Insects
antagonists
insects
receptors
9 Citations (Scopus)

Defining disease, diagnosis, and translational medicine within a homeostatic perturbation paradigm: The National Institutes of Health undiagnosed diseases program experience

Gall, T., Valkanas, E., Bello, C., Markello, T., Adams, C., Bone, W. P., Brandt, A. J., Brazill, J. M., Carmichael, L., Davids, M., Davis, J., Diaz-Perez, Z., Draper, D., Elson, J., Flynn, E. D., Godfrey, R., Groden, C., Hsieh, C. K., Fischer, R., Golas, G. A. & 31 others, Guzman, J., Huang, Y., Kane, M. S., Lee, E., Li, C., Links, A. E., Maduro, V., Malicdan, M. C. V., Malik, F. S., Nehrebecky, M., Park, J., Pemberton, P., Schaffer, K., Simeonov, D., Sincan, M., Smedley, D., Valivullah, Z., Wahl, C., Washington, N., Wolfe, L. A., Xu, K., Zhu, Y., Gahl, W. A., Tifft, C. J., Toro, C., Adams, D. R., He, M., Robinson, P. N., Haendel, M. A., Zhai, R. G. & Boerkoel, C. F., Jan 1 2017, In : Frontiers in Medicine. 4, MAY, 62.

Research output: Contribution to journalArticle

Open Access
Translational Medical Research
National Institutes of Health (U.S.)
Genetic Association Studies
Patient Care
Genotype
16 Citations (Scopus)

Developing a data sharing community for spinal cord injury research

Callahan, A., Anderson, K. D., Beattie, M. S., Bixby, J., Ferguson, A. R., Fouad, K., Jakeman, L. B., Nielson, J. L., Popovich, P. G., Schwab, J. M. & Lemmon, V., Sep 1 2017, In : Experimental Neurology. 295, p. 135-143 9 p.

Research output: Contribution to journalReview article

Information Dissemination
Spinal Cord Injuries
Research
Education
National Institute of Neurological Disorders and Stroke
13 Citations (Scopus)

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop

Jagodnik, K. M., Koplev, S., Jenkins, S. L., Ohno-Machado, L., Paten, B., Schuerer, S. C., Dumontier, M., Verborgh, R., Bui, A., Ping, P., McKenna, N. J., Madduri, R., Pillai, A. & Ma'ayan, A., Jul 1 2017, In : Journal of Biomedical Informatics. 71, p. 49-57 9 p.

Research output: Contribution to journalArticle

Biomedical Research
Education
Information Dissemination
Ecosystem
Research Personnel
8 Citations (Scopus)

Drug target ontology to classify and integrate drug discovery data

Lin, Y., Mehta, S., Küçük-McGinty, H., Turner, J. P., Vidovic, D., Forlin, M., Koleti, A., Nguyen, D. T., Jensen, L. J., Guha, R., Mathias, S. L., Ursu, O., Stathias, V., Duan, J., Nabizadeh, N., Chung, C., Mader, C., Visser, U. E., Yang, J. J., Bologa, C. G. & 2 others, Oprea, T. I. & Schuerer, S. C., Nov 9 2017, In : Journal of Biomedical Semantics. 8, 1, 50.

Research output: Contribution to journalArticle

Drug Discovery
Ontology
Pharmaceutical Preparations
Proteins
Genes
61 Citations (Scopus)

Enhanced cardioprotection by human endometrium mesenchymal stem cells driven by exosomal MicroRNA-21

Wang, K., Jiang, Z., Webster, K. A., Chen, J., Hu, H., Zhou, Y., Zhao, J., Wang, L., Wang, Y., Zhong, Z., Ni, C., Li, Q., Xiang, C., Zhang, L., Wu, R., Zhu, W., Yu, H., Hu, X. & Wang, JA., Jan 1 2017, In : Stem cells translational medicine. 6, 1, p. 209-222 14 p.

Research output: Contribution to journalArticle

Endometrium
MicroRNAs
Mesenchymal Stromal Cells
Bone Marrow
Cell- and Tissue-Based Therapy
6 Citations (Scopus)

From flamingo dance to (desirable) drug discovery: A nature-inspired approach

Sánchez-Rodríguez, A., Pérez-Castillo, Y., Schuerer, S. C., Nicolotti, O., Mangiatordi, G. F., Borges, F., Cordeiro, M. N. D. S., Tejera, E., Medina-Franco, J. L. & Cruz-Monteagudo, M., 2017, (Accepted/In press) In : Drug Discovery Today.

Research output: Contribution to journalArticle

Drug Discovery
Therapeutic Uses
Industry
Pharmaceutical Preparations
Machine Learning
1 Citation (Scopus)

Functional and nonfunctional forms of CquiOR91, an odorant selectivity subunit of Culex quinquefasciatus

Hughes, D. T., Pelletier, J., Rahman, S., Chen, S., Leal, W. S. & Luetje, C. W., May 1 2017, In : Chemical Senses. 42, 4, p. 333-341 9 p., bjx011.

Research output: Contribution to journalArticle

Culex
DEET
Odorant Receptors
Alleles
Ligands
3 Citations (Scopus)

Functional characterizations of rare UBA1 variants in X-linked Spinal Muscular Atrophy

Baumbach-Reardon, L., Balak, C. D., Hunter, J. M., Ahearn, M. E., Wiley, D. & D'urso, G., 2017, In : F1000Research. 6, 1636.

Research output: Contribution to journalArticle

Spinal Muscular Atrophy
Ubiquitin
Mutation
Assays
Missense Mutation

Genetically modifying transcription factors to promote CNS axon regeneration

Mehta, S. T., Bixby, J. & Lemmon, V., May 1 2017, In : Neural Regeneration Research. 12, 5, p. 737-738 2 p.

Research output: Contribution to journalComment/debate

Axons
Regeneration
Transcription Factors
16 Citations (Scopus)

Glucose-stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets

Buchwald, P., Tamayo-Garcia, A., Manzoli, V., Tomei, A. & Stabler, C. L., 2017, (Accepted/In press) In : Biotechnology and Bioengineering.

Research output: Contribution to journalArticle

Hydrogel
Insulin
Islets of Langerhans
Hydrogels
Glucose
10 Citations (Scopus)
Muscle Fatigue
Ryanodine Receptor Calcium Release Channel
Muscle Strength
Muscle
Skeletal Muscle
9 Citations (Scopus)

Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice

Yuan, C. C., Kazmierczak, K., Liang, J., Takeuchi, R., Irving, T. C., Gomes, A. V., Wang, Y., Burghardt, T. P. & Szczesna-Cordary, D., Aug 1 2017, In : Cardiovascular Research. 113, 10, p. 1124-1136 13 p.

Research output: Contribution to journalArticle

Restrictive Cardiomyopathy
Ventricular Myosins
Myosin Light Chains
Myosins
Papillary Muscles
3 Citations (Scopus)

Hypoxic Stress Decreases c-Myc Protein Stability in Cardiac Progenitor Cells Inducing Quiescence and Compromising Their Proliferative and Vasculogenic Potential

Bellio, M. A., Pinto, M. T., Florea, V., Barrios, P. A., Taylor, C. N., Brown, A. B., Lamondin, C., Hare, J., Schulman, I. H. & Rodrigues, C. D., Dec 1 2017, In : Scientific Reports. 7, 1, 9702.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-myc
Protein Stability
Stem Cells
Cell Cycle Resting Phase
Cytoprotection
6 Citations (Scopus)

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

Allen, B. K., Mehta, S., Ember, S. W. J., Zhu, J. Y., Schönbrunn, E., Ayad, N. & Schuerer, S. C., Jan 1 2017, In : ACS Omega. 2, 8, p. 4760-4771 12 p.

Research output: Contribution to journalArticle

Open Access
Screening
Ligands
Proteins
Molecular dynamics
Computer simulation
9 Citations (Scopus)

Identification of miRNAs involved in DRG neurite outgrowth and their putative targets

Motti, D., Lerch, J. K., Danzi, M. C., Gans, J. H., Kuo, F., Slepak, T. I., Bixby, J. & Lemmon, V., 2017, (Accepted/In press) In : FEBS Letters.

Research output: Contribution to journalArticle

Diagnosis-Related Groups
MicroRNAs
Protein Isoforms
Neurites
Neurons
4 Citations (Scopus)

Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit

Kepchia, D., Moliver, S., Chohan, K., Phillips, C. & Luetje, C. W., May 1 2017, In : PLoS One. 12, 5, e0177454.

Research output: Contribution to journalArticle

Odorant Receptors
Insects
antagonists
insects
receptors
1 Citation (Scopus)

Learning reference-enriched approach towards large scale active ontology alignment and integration

Cheng, Q., Ursu, O., Oprea, T. I. & Schuerer, S. C., Dec 15 2017, Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017. Institute of Electrical and Electronics Engineers Inc., Vol. 2017-January. p. 1658-1663 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Systems Integration
Ontology
Unified Medical Language System
Learning
4 Citations (Scopus)
Grafts
Scaffolds
Polydimethylsiloxane
Transplants
Islets of Langerhans Transplantation
1 Citation (Scopus)

Loss of c-Kit function impairs arteriogenesis in a mouse model of hindlimb ischemia

Hernandez, D. R., Artiles, A., Duque, J. C., Martinez, L., Pinto, M. T., Webster, K. A., Velazquez, O. C., Vazquez-Padron, R. I. & Soares, R., Jan 1 2017, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journalArticle

Hindlimb
Ischemia
Blood Vessels
Foot
Bone Marrow Transplantation
1 Citation (Scopus)

Mammalian odorant receptor tuning breadth persists across distinct odorant panels

Kepchia, D., Sherman, B., Haddad, R. & Luetje, C. W., Sep 1 2017, In : PLoS One. 12, 9, e0185329.

Research output: Contribution to journalArticle

Odorant Receptors
odor compounds
Tuning
screening
Odors
10 Citations (Scopus)

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Garcia-Contreras, M., Tamayo-Garcia, A., Pappan, K. L., Michelotti, G. A., Stabler, C. L., Ricordi, C. & Buchwald, P., Jun 2 2017, In : Journal of Proteome Research. 16, 6, p. 2294-2306 13 p.

Research output: Contribution to journalArticle

Metabolomics
Islets of Langerhans
Insulin
Inflammation
Glucose
4 Citations (Scopus)

Mutant cycle analysis identifies a ligand interaction site in an odorant receptor of the malaria vector Anopheles gambiae

Rahman, S. & Luetje, C. W., Jan 1 2017, In : Journal of Biological Chemistry. 292, 46, p. 18916-18923 8 p.

Research output: Contribution to journalArticle

Odorant Receptors
Anopheles gambiae
Malaria
Ligands
Insects
16 Citations (Scopus)

Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way

Zhu, J., Lu, K., Zhang, N., Zhao, Y., Ma, Q., Shen, J., Lin, Y., Xiang, P., Tang, Y., Hu, X., Chen, J., Zhu, W., Webster, K. A., Wang, J. & Yu, H., Nov 14 2017, (Accepted/In press) In : Artificial Cells, Nanomedicine and Biotechnology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Exosomes
Sphingomyelin Phosphodiesterase
Cell Hypoxia
Stem cells
MicroRNAs
10 Citations (Scopus)

Nitric Oxide Regulates Skeletal Muscle Fatigue, Fiber Type, Microtubule Organization, and Mitochondrial ATP Synthesis Efficiency Through cGMP-Dependent Mechanisms

Moon, Y., Balke, J. E., Madorma, D., Siegel, M. P., Knowels, G., Brouckaert, P., Buys, E. S., Marcinek, D. J. & Percival, J., Jun 10 2017, In : Antioxidants and Redox Signaling. 26, 17, p. 966-985 20 p.

Research output: Contribution to journalArticle

Muscle Fatigue
Guanylate Cyclase
Skeletal Muscle Fibers
Microtubules
Muscle
16 Citations (Scopus)

NMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector

Brazill, J. M., Li, C., Zhu, Y. & Zhai, R. G., Jun 1 2017, In : Current Opinion in Genetics and Development. 44, p. 156-162 7 p.

Research output: Contribution to journalReview article

Nicotinamide Mononucleotide
NAD
Maintenance
Wallerian Degeneration
Proteins
5 Citations (Scopus)

Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses

Ong, E., Xie, J., Ni, Z., Liu, Q., Sarntivijai, S., Lin, Y., Cooper, D., Terryn, R., Stathias, V., Chung, C., Schuerer, S. C. & He, Y., Dec 21 2017, In : BMC Bioinformatics. 18, 556.

Research output: Contribution to journalArticle

Libraries
Signature
Cells
Cell Line
Line