Molecular and Cellular Pharmacology

Research Output 1974 2019

2019
2 Citations (Scopus)

A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

Qadir, M. M. F., Álvarez-Cubela, S., Belle, K., Sapir, T., Messaggio, F., Johnson, K. B., Umland, O., Hardin, D., Klein, D., Pérez-Álvarez, I., Sadiq, F., Alcázar, O., Inverardi, L. A., Ricordi, C., Buchwald, P., Fraker, C. A., Pastori, R. L. & Domínguez-Bendala, J., Mar 5 2019, In : Stem Cell Reports. 12, 3, p. 611-623 13 p.

Research output: Contribution to journalArticle

Open Access
Stem cells
Carcinogenesis
Insulin
Prodrugs
Cell death

A Gene Family-led Meta-Analysis of Drug-Target Interactions

Cheng, Q., Mehta, S. & Schuerer, S. C., Jan 21 2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1618-1623 6 p. 8621087. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Drug Interactions
Drug products
Meta-Analysis
Lead
Genes
1 Citation (Scopus)
Open Access
Ligands
Signal Transduction
Binding Sites
Pharmacology
1 Citation (Scopus)

Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer

Zhao, N., Peacock, S. O., Lo, C. H., Heidman, L. M., Rice, M. A., Fahrenholtz, C. D., Greene, A. M., Magani, F., Copello, V. A., Martinez, M. J., Zhang, Y., Daaka, Y., Lynch, C. C. & Burnstein, K. L., Jan 1 2019, In : Science Translational Medicine. 11, 498, eaaw4636.

Research output: Contribution to journalArticle

Vasopressin Receptors
Castration
Androgen Receptors
Prostatic Neoplasms
Androgens
8 Citations (Scopus)

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

Hutson, T. H., Kathe, C., Palmisano, I., Bartholdi, K., Hervera, A., De Virgiliis, F., McLachlan, E., Zhou, L., Kong, G., Barraud, Q., Danzi, M. C., Medrano-Fernandez, A., Lopez-Atalaya, J. P., Boutillier, A. L., Sinha, S. H., Singh, A. K., Chaturbedy, P., Moon, L. D. F., Kundu, T. K., Bixby, J. & 4 others, Lemmon, V., Barco, A., Courtine, G. & Giovanni, S. D., Apr 10 2019, In : Science Translational Medicine. 11, 487, eaaw2064.

Research output: Contribution to journalArticle

Acetylation
Spinal Cord Injuries
Histones
Axons
Regeneration

CD40-targeting KGYY15 peptides do not efficiently block the CD40–CD40L interaction

Bojadzic, D. & Buchwald, P., Jan 1 2019, (Accepted/In press) In : Diabetologia.

Research output: Contribution to journalLetter

CD40 Ligand
Peptides
Open Access
Insulin
Glucose
Artificial Pancreas
Sigmoid Colon
Islets of Langerhans

Correction to: In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice (Diabetologia, (2019), 62, 7, (1237-1250), 10.1007/s00125-019-4879-0)

Abdulreda, M. H., Molano, R. D., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. S., Ricordi, C., Caicedo, A., Buchwald, P., Pileggi, A. & Berggren, P. O., Jan 1 2019, In : Diabetologia.

Research output: Contribution to journalComment/debate

Inbred NOD Mouse
Type 1 Diabetes Mellitus
8 Citations (Scopus)

DrugCentral 2018: an update

Ursu, O., Holmes, J., Bologa, C. G., Yang, J. J., Mathias, S. L., Stathias, V., Nguyen, D. T., Schuerer, S. C. & Oprea, T., Jan 8 2019, In : Nucleic Acids Research. 47, D1, p. D963-D970

Research output: Contribution to journalArticle

Information Storage and Retrieval
United States Food and Drug Administration
Pharmaceutical Preparations
Databases
Literature

Dysfunction of GRAP, encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss

Li, C., Bademci, G., Subasioglu, A., Diaz-Horta, O., Zhu, Y., Liu, J., Mitchell, T. G., Abad, C., Seyhan, S., Duman, D., Cengiz, F. B., Tokgoz-Yilmaz, S., Blanton, S. H., Farooq, A., Walz, K., Zhai, R. G. & Tekin, M., Jan 22 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 4, p. 1347-1352 6 p.

Research output: Contribution to journalArticle

GRB2 Adaptor Protein
Sensorineural Hearing Loss
Phosphotransferases
Proteins
Auditory Hair Cells

Efficient proximal gradient algorithm for inference of differential gene networks

Wang, C., Gao, F., Giannakis, G. B., D'urso, G. & Cai, X., May 2 2019, In : BMC Bioinformatics. 20, 1, 224.

Research output: Contribution to journalArticle

Open Access
Proximal Algorithm
Gene Networks
Gene Regulatory Networks
Gradient Algorithm
Genes

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216), (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., Jermakowicz, A. M., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D. G., Watts, J., Vega, F. & Nimer, S. D., Jan 14 2019, In : Cancer Cell. 35, 1, 1 p.

Research output: Contribution to journalComment/debate

Hematopoiesis
Names
Neoplasms
coactivator-associated arginine methyltransferase 1

Feasibility of localized metabolomics in the study of pancreatic islets and diabetes

Alcazar, O., Hernandez, L. F., Tschiggfrie, A., Muehlbauer, M. J., Bain, J. R., Buchwald, P. & Abdulreda, M. H., Oct 2019, In : Metabolites. 9, 10, 207.

Research output: Contribution to journalArticle

Open Access
Metabolomics
Aqueous Humor
Medical problems
Metabolites
Islets of Langerhans
1 Citation (Scopus)
Cardiac Myosins
Myosin Light Chains
Inborn Genetic Diseases
Cardiomyopathies
Heart Diseases

How to develop a drug target ontology: KNowledge acquisition and representation methodology (KNARM)

Küçük McGinty, H., Visser, U. E. & Schuerer, S. C., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 49-69 21 p. (Methods in Molecular Biology; vol. 1939).

Research output: Chapter in Book/Report/Conference proceedingChapter

Biological Science Disciplines
Semantics
Pharmaceutical Preparations
Information Storage and Retrieval
Drug Discovery

Identification of suppressor of Clathrin deficiency-1 (SCD1) and its connection to Clathrin-mediated endocytosis in Saccharomyces cerevisiae

Moorthy, B. T., Sharma, A., Boettner, D. R., Wilson, T. E. & Lemmon, S., Mar 1 2019, In : G3: Genes, Genomes, Genetics. 9, 3, p. 867-877 11 p.

Research output: Contribution to journalArticle

Open Access
Clathrin
Endocytosis
Saccharomyces cerevisiae
Clathrin Heavy Chains
Yeasts
Open Access
toxicology
annotations
metadata
Metadata
Toxicology
5 Citations (Scopus)

Inflammasome activation induces pyroptosis in the retina exposed to ocular hypertension injury

Pronin, A., Pham, D., An, W., Dvoriantchikova, G., Reshetnikova, G., Qiao, J., Kozhekbaeva, Z., Reiser, A. E., Slepak, V. Z. & Shestopalov, V. I., Feb 12 2019, In : Frontiers in Molecular Neuroscience. 12, 36.

Research output: Contribution to journalArticle

Open Access
Inflammasomes
Eye Injuries
Ocular Hypertension
Retina
Neuroglia

Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing

Kumar, A., Birnbaum, M. D., Moorthy, B. T., Singh, J., Palovcak, A., Patel, D. M. & Zhang, F., Jul 24 2019, In : BMC genomics. 20, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Fluorescence
DNA
Proteins
Genome
Clustered Regularly Interspaced Short Palindromic Repeats
Myosin Light Chains
Muscle Development
Myosin Type II
Muscle
Myocardium
1 Citation (Scopus)

In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice

Abdulreda, M. H., Molano, R. D., Faleo, G., Lopez-Cabezas, M., Shishido, A., Ulissi, U., Fotino, C., Hernandez, L. F., Tschiggfrie, A., Aldrich, V. R., Tamayo-Garcia, A., Bayer, A. L., Ricordi, C., Caicedo-Vierkant, D. A., Buchwald, P., Pileggi, A. & Berggren, P. O., Jan 1 2019, In : Diabetologia.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
Anterior Chamber
Islets of Langerhans
Autoimmunity
4 Citations (Scopus)

Neuronal nitric oxide synthase (nNOS) splice variant function: Insights into nitric oxide signaling from skeletal muscle

Balke, J. E., Zhang, L. & Percival, J. M., Jan 1 2019, In : Nitric Oxide - Biology and Chemistry. 82, p. 35-47 13 p.

Research output: Contribution to journalReview article

Nitric Oxide Synthase Type I
Muscle
Nitric Oxide
Skeletal Muscle
Cell signaling
1 Citation (Scopus)

Novel Curcumin inspired bis-chalcone promotes endoplasmic reticulum stress and glioblastoma neurosphere cell death

Sansalone, L., Veliz, E. A., Myrthil, N. G., Stathias, V., Walters, W., Torrens, I. I., Schürer, S. C., Vanni, S., Leblanc, R. M. & Graham, R. M., Mar 1 2019, In : Cancers. 11, 3, 357.

Research output: Contribution to journalArticle

Open Access
Chalcone
Endoplasmic Reticulum Stress
Curcumin
Glioblastoma
Cell Death
1 Citation (Scopus)

OSCI: Standardized stem cell ontology representation and use cases for stem cell investigation

He, Y., Duncan, W. D., Cooper, D. J., Hansen, J., Iyengar, R., Ong, E., Walker, K., Tibi, O., Smith, S., Serra, L. M., Zheng, J., Sarntivijai, S., Schuerer, S. C., O'shea, K. S. & Diehl, A. D., Apr 25 2019, In : BMC Bioinformatics. 20, 180.

Research output: Contribution to journalArticle

Open Access
Stem Cells
Use Case
Stem cells
Ontology
Cell

Parallel evaluation of two promising immunoisolation strategies for beta cell replacement: Conformal coating versus double alginate encapsulation

Toni, T. D., Stock, A. A., Safley, S. A., Weber, C., Alcazar, O., Buchwald, P. & Tomei, A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Alginate
Encapsulation
Glucose
Insulin
Hydrogels

Progenitor/Stem Cell Delivery by Suprarenal Aorta Route in Acute Kidney Injury

Rangel, É. B., Gomes, S. A., Kanashiro-Takeuchi, R. & Hare, J. M., Nov 1 2019, In : Cell Transplantation. 28, 11, p. 1390-1403 14 p.

Research output: Contribution to journalArticle

Open Access
Stem cells
Acute Kidney Injury
Aorta
Stem Cells
Puromycin Aminonucleoside

Research Techniques Made Simple: Molecular Docking in Dermatology - A Foray into In Silico Drug Discovery

Issa, N. T., Badiavas, E. V. & Schürer, S., Dec 2019, In : Journal of Investigative Dermatology. 139, 12, p. 2400-2408.e1

Research output: Contribution to journalShort survey

Open Access
Dermatology
Drug Discovery
Computer Simulation
Research Design
Molecular modeling

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy

Parvatiyar, M. S., Brownstein, A. J., Takeuchi, R., Collado, J. R., Dieseldorff Jones, K. M., Gopal, J., Hammond, K. G., Marshall, J. L., Ferrel, A., Beedle, A. M., Chamberlain, J. S., Pinto, J. R. & Crosbie, R. H., Jun 6 2019, In : JCI Insight. 4, 11, e123855.

Research output: Contribution to journalArticle

Open Access
Sarcolemma
Duchenne Muscular Dystrophy
Cardiomyopathies
Utrophin
Dystrophin

Therapeutic potential of AAV9-S15D-RLC gene delivery in humanized MYL2 mouse model of HCM

Yadav, S., Yuan, C. C., Kazmierczak, K., Liang, J., Huang, W., Takeuchi, L. M., Takeuchi, R. & Szczesna-Cordary, D., Jan 1 2019, In : Journal of Molecular Medicine.

Research output: Contribution to journalArticle

Dependovirus
Hypertrophic Cardiomyopathy
Genes
Phosphorylation
Therapeutics
2 Citations (Scopus)

Use of machine learning to identify novel, behaviorally active antagonists of the insect odorant receptor co-receptor (Orco) subunit

Kepchia, D., Xu, P., Terryn, R., Castro, A., Schuerer, S. C., Leal, W. S. & Luetje, C. W., Dec 1 2019, In : Scientific reports. 9, 1, 4055.

Research output: Contribution to journalArticle

Open Access
Odorant Receptors
Insects
Drosophila melanogaster
Machine Learning
Insect Repellents
2018
1 Citation (Scopus)

Alterations of tumor microenvironment by nitric oxide impedes castration-resistant prostate cancer growth

Arora, H., Panara, K., Kuchakulla, M., Kulandavelu, S., Burnstein, K. L., Schally, A. V., Hare, J. & Ramasamy, R., Oct 30 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 44, p. 11298-11303 6 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Castration
Prostatic Neoplasms
Nitric Oxide
Growth

A Rapid and Precise Mutation-Activated Fluorescence Reporter for Analyzing Acute Mutagenesis Frequency

Birnbaum, M. D., Nemzow, L., Kumar, A., Gong, F. & Zhang, F., Jan 1 2018, (Accepted/In press) In : Cell Chemical Biology.

Research output: Contribution to journalArticle

Mutagenesis
Fluorescence
Mutation
Biosensing Techniques
Cell death
2 Citations (Scopus)

Can Chromatin Accessibility be Exploited for Axon Regeneration?

Danzi, M. C., O’Neill, N., Bixby, J. & Lemmon, V., Jan 1 2018, (Accepted/In press) In : Developmental Neurobiology.

Research output: Contribution to journalArticle

Chromatin
Axons
Regeneration
Histone Acetyltransferases
Histone Deacetylases
7 Citations (Scopus)

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathais, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schuerer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F-C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Jun 11 2018, In : Cancer Cell. 33, 6, p. 1111-1127.e5

Research output: Contribution to journalArticle

Hematopoiesis
Acute Myeloid Leukemia
Cell Cycle
Protein-Arginine N-Methyltransferases
Apoptosis
5 Citations (Scopus)

Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast

Isom, D. G., Page, S. C., Collins, L. B., Kapolka, N. J., Taghon, G. J. & Dohlman, H. G., Jan 1 2018, In : Journal of Biological Chemistry. 293, 7, p. 2318-2329 12 p.

Research output: Contribution to journalArticle

Sugars
Yeast
Yeasts
Glucose
Metabolism
29 Citations (Scopus)

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: Integrated access to diverse large-scale cellular perturbation response data

Koleti, A., Terryn, R., Stathias, V., Chung, C., Cooper, D. J., Turner, J. P., VidoviÄ ‡, D., Forlin, M., Kelley, T. T., D'Urso, A., Allen, B. K., Torre, D., Jagodnik, K. M., Wang, L., Jenkins, S. L., Mader, C., Niu, W., Fazel, M., Mahi, N., Pilarczyk, M. & 9 others, Clark, N., Shamsaei, B., Meller, J., Vasiliauskas, J., Reichard, J., Medvedovic, M., Ma'Ayan, A., Pillai, A. & Schuerer, S. C., Jan 1 2018, In : Nucleic Acids Research. 46, D1, p. D558-D566

Research output: Contribution to journalArticle

Libraries
Cataloging
Registries
Software
Databases
3 Citations (Scopus)

Design, synthesis, and evaluation of novel immunomodulatory small molecules targeting the CD40–CD154 costimulatory protein-protein interaction

Bojadzic, D., Chen, J., Alcazar, O. & Buchwald, P., Jan 1 2018, In : Molecules. 23, 5, 1153.

Research output: Contribution to journalArticle

Assays
T-cells
plan position indicators
Biological Products
proteins
5 Citations (Scopus)

Drug and disease signature integration identifies synergistic combinations in glioblastoma

Stathias, V., Jermakowicz, A. M., Maloof, M. E., Forlin, M., Walters, W., Suter, R. K., Durante, M. A., Williams, S. L., Harbour, J. W., Volmar, C. H., Lyons, N. J., Wahlestedt, C., Graham, R. M., Ivan, M. E., Komotar, R. J., Sarkaria, J. N., Subramanian, A., Golub, T. R., Schürer, S. C. & Ayad, N. G., Dec 1 2018, In : Nature Communications. 9, 1, 5315.

Research output: Contribution to journalArticle

Glioblastoma
drugs
signatures
Gene expression
Genes
13 Citations (Scopus)

Drug repositioning in glioblastoma: A pathway perspective

Tan, S. K., Jermakowicz, A., Mookhtiar, A. K., Nemeroff, C., Schuerer, S. C. & Ayad, N., Mar 16 2018, In : Frontiers in Pharmacology. 9, MAR, 218.

Research output: Contribution to journalReview article

Drug Repositioning
Glioblastoma
Cell Death
Therapeutics
Drug Delivery Systems

Erratum: CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis (Cancer Cell (2018) 33(6) (1111–1127.e5), (S1535610818302216) (10.1016/j.ccell.2018.05.007))

Greenblatt, S. M., Man, N., Hamard, P. J., Asai, T., Karl, D., Martinez, C., Bilbao, D., Stathias, V., McGrew-Jermacowicz, A., Duffort, S., Tadi, M., Blumenthal, E., Newman, S., Vu, L., Xu, Y., Liu, F., Schurer, S. C., McCabe, M. T., Kruger, R. G., Xu, M. & 5 others, Yang, F. C., Tenen, D., Watts, J., Vega, F. & Nimer, S. D., Nov 12 2018, In : Cancer Cell. 34, 5, 1 p.

Research output: Contribution to journalComment/debate

Hematopoiesis
Names
Neoplasms
coactivator-associated arginine methyltransferase 1
7 Citations (Scopus)

Erratum: Unexplored therapeutic opportunities in the human genome (Nature reviews. Drug discovery (2018) 17 5 (317-332))

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., von Mering, C., Muthas, D., Nguyen, D. T., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schürer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidovic, D., Waller, A., Westergaard, D., Yang, J. J. & Zahoránszky-Köhalmi, G., May 1 2018, In : Nature reviews. Drug discovery. 17, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Human Genome
Drug Discovery
Therapeutics

Erratum: Publisher Correction: Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome (Nature communications (2017) 8 1 (1257))

Li, C., Brazill, J. M., Liu, S., Bello, C., Zhu, Y., Morimoto, M., Cascio, L., Pauly, R., Diaz-Perez, Z., Malicdan, M. C. V., Wang, H., Boccuto, L., Schwartz, C. E., Gahl, W. A., Boerkoel, C. F. & Zhai, R. G., Jan 18 2018, In : Nature Communications. 9, 1, 1 p.

Research output: Contribution to journalComment/debate

Spermine Synthase
Sagittaria
Oxidative stress
Manuscripts
Oxidative Stress
3 Citations (Scopus)

Far away from the lamppost

Oprea, T. I., Jan, L., Johnson, G. L., Roth, B. L., Ma’ayan, A., Schuerer, S. C., Shoichet, B. K., Sklar, L. A. & McManus, M. T., Dec 1 2018, In : PLoS Biology. 16, 12, e3000067.

Research output: Contribution to journalArticle

Research
funding
Genes
Genome
genome

High content screening of mammalian primary cortical neurons

Motti, D., Blackmore, M., Bixby, J. & Lemmon, V., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1683. p. 293-304 12 p. (Methods in Molecular Biology; vol. 1683).

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurites
Neurons
Growth
Pyramidal Tracts
Motor Cortex
1 Citation (Scopus)

Identification of an oncogenic network with prognostic and therapeutic value in prostate cancer

Magani, F., Bray, E. R., Martinez, M. J., Zhao, N., Copello, V. A., Heidman, L., Peacock, S. O., Wiley, D. J., D'urso, G. & Burnstein, K. L., Aug 1 2018, In : Molecular Systems Biology. 14, 8, e8202.

Research output: Contribution to journalArticle

Prostate Cancer
Androgen Receptors
prostatic neoplasms
Prostatic Neoplasms
Genes
3 Citations (Scopus)

Kidney-derived c-kit+ progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria

Rangel, E. B., Gomes, S. A., Takeuchi, R., Saltzman, R. G., Wei, C., Ruiz, P., Reiser, J. & Hare, J., Dec 1 2018, In : Scientific Reports. 8, 1, 14723.

Research output: Contribution to journalArticle

Podocytes
Proteinuria
Stem Cells
Kidney
Foot
11 Citations (Scopus)

Mutations in ATP1A1 Cause Dominant Charcot-Marie-Tooth Type 2

Lassuthova, P., Rebelo, A. P., Ravenscroft, G., Lamont, P. J., Davis, M. R., Manganelli, F., Feely, S. M., Bacon, C., Brožková, D. Š., Haberlova, J., Mazanec, R., Tao, F., Saghira, C., Abreu, L., Courel, S., Powell, E., Buglo, E., Bis, D. M., Baxter, M. F., Ong, R. W. & 14 others, Marns, L., Lee, Y. C., Bai, Y., Isom, D. G., Barro-Soria, R., Chung, K. W., Scherer, S. S., Larsson, H. P., Laing, N. G., Choi, B. O., Seeman, P., Shy, M. E., Santoro, L. & Zuchner, S., Mar 1 2018, In : American Journal of Human Genetics. 102, 3, p. 505-514 10 p.

Research output: Contribution to journalArticle

Axons
Tooth
Mutation
Information Dissemination
Genetic Association Studies
5 Citations (Scopus)

Nmnat mitigates sensory dysfunction in a Drosophila model of paclitaxel-induced peripheral neuropathy

Brazill, J. M., Cruz, B., Zhu, Y. & Zhai, R. G., Jun 1 2018, In : DMM Disease Models and Mechanisms. 11, 6, dmm.032938.

Research output: Contribution to journalArticle

Nicotinamide-Nucleotide Adenylyltransferase
Chemotherapy
Peripheral Nervous System Diseases
Paclitaxel
Drosophila
Nitric Oxide Synthase Type I
Papillary Muscles
Myofibrils
myofibrils
myocardium
2 Citations (Scopus)

Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells

Dvoriantchikova, G., Pronin, A., Kurtenbach, S., Toychiev, A., Chou, T. H., Yee, C. W., Prindeville, B., Tayou, J., Porciatti, V., Sagdullaev, B. T., Slepak, V. Z. & Shestopalov, V. I., Dec 1 2018, In : Scientific Reports. 8, 1, 5797.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Retina
Ocular Hypertension
Mechanical Stress
Intraocular Pressure