Molecular and Cellular Pharmacology

Projects 1976 2024

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Molecules
Proteins
Transplants
Pharmaceutical Preparations
Ligands
Blood Vessels
Cardiovascular Diseases
Stem Cells
Endothelial Cells
Homeostasis

Binding Site Structure of Insect Odorant Receptors.

Luetje, C. W.

National Institutes of Health

6/1/105/31/16

Project: Research project

Odorant Receptors
binding sites
insects
Insects
receptors

BINDING SITE STRUCTURE OF NEURONAL NICOTINIC RECEPTORS

Luetje, C. W.

National Institutes of Health

3/1/945/31/05

Project: Research project

Nicotinic Receptors
Binding Sites
Pharmacology
Amino Acids
Ligands
Bioassay
Ontology
Assays
Screening
Throughput

CA2+ REGULATION OF MUSCLE CONTRACTION

Potter, J. D.

National Institutes of Health

7/1/868/31/97

Project: Research project

Muscle Contraction
Troponin
Troponin C
Muscles
Myofibrils

CARDIOCYTE RESPONSES TO HYPOXIA

Webster, K. A.

National Institutes of Health

4/1/903/31/12

Project: Research project

Cardiac Myocytes
Ischemia
Reperfusion
Apoptosis
Phosphotransferases
Morphogenesis
Phosphotransferases
Growth
Cell Polarity
Cell Shape

Detection of Melanoma by Canine Olfactory Receptors.

Abaffy, T.

National Institutes of Health

9/29/088/31/11

Project: Research project

Odorant Receptors
Canidae
Melanoma
Aptitude
Biomarkers
Neurons
Drosophila
Protein Isoforms
Alternative Splicing
Mammals

FHC Tn Mutations: Functional Consequences &Mechanisms

Potter, J. D.

National Institutes of Health

7/25/026/30/07

Project: Research project

Familial Hypertrophic Cardiomyopathy
Mutation
Troponin T
Troponin
Sudden Cardiac Death
Clathrin
Molecular Biology
Yeasts
Clathrin Heavy Chains
Genes

Genetic Mechanisms of Motor Neuron Degeneration

Kim, M. D.

National Institutes of Health

9/1/102/28/13

Project: Research project

Nerve Degeneration
Motor Neurons
Amyotrophic Lateral Sclerosis
Drosophila
Genes
Androgen Receptors
Androgens
Complementary DNA
Messenger RNA
Steroids

HORMONE REGULATION OF PHOSPHOINOSITIDE BREAKDOWN

Litosch, I.

National Institutes of Health

9/20/858/31/88

Project: Research project

hormones
cell free system
phosphatidylinositols
Calliphora vicina
inositol phosphates

HORMONE REGULATION OF PHOSPHOINOSITIDE HYDROLYSIS

Litosch, I.

National Institutes of Health

9/20/8511/30/95

Project: Research project

Phosphatidylinositols
GTP-Binding Proteins
Hydrolysis
Hormones
hormones

HTS for Regulated Muscle Thin Filament Function.

Potter, J. D.

National Institutes of Health

9/30/0810/31/11

Project: Research project

Troponin C
Cardiomyopathies
Restrictive Cardiomyopathy
Myocardium
Troponin
RGS Proteins
G-Protein-Coupled Receptors
GTP-Binding Proteins
GTPase-Activating Proteins
Signal Transduction
JNK Mitogen-Activated Protein Kinases
Reperfusion Injury
Hyperglycemia
Insulin Resistance
Reperfusion

Ligand Recognition Among Mammalian Odorant Receptors

Luetje, C. W.

National Institutes of Health

4/1/089/30/12

Project: Research project

Odorant Receptors
Ligands
G-Protein-Coupled Receptors
Pharmaceutical Preparations
Sequence Analysis
Transducin
Retinal Rod Photoreceptor Cells
Ocular Adaptation
Light
GTP-Binding Proteins
Information systems
Ontology
Assays
Screening
Bioassay

MECHANISM OF CARDIAC MUSCLE REGULATION BY TROPONIN

Potter, J. D. & Szczesna-Cordary, D.

National Institutes of Health

4/1/892/28/13

Project: Research project

Troponin
Myocardium
Familial Hypertrophic Cardiomyopathy
Muscle Contraction
Troponin T
Maintenance
Neurons
Drosophila
Housekeeping
Proteins
Muscles
Motor Neurons
Synapses
Lambert-Eaton Myasthenic Syndrome
Neuromuscular Diseases

MOLECULAR MECHANISMS OF CONTRACTION

Potter, J. D., Mandel, F., Lane, L., Wang, T., Collins, J., Millard, R., Wallick, E., Brown, T., Jackson, R., Johnson, C., Wieczorek, D., Liggett, S., Disalvo, J., Robbins, J., Kranias, E., Varadi, G., Grupp, I. & Schwartz, A.

National Institutes of Health

7/1/786/30/05

Project: Research project

Muscle Contraction
Myocardium
Myosin Type I
Reticulum
Troponin I
Stem Cells
Myocardium
Cell- and Tissue-Based Therapy
Transplantation
Cardiovascular Diseases

MUTATION OF SKELETAL TROPONIN C FUNCTIONAL DOMAINS

Potter, J. D.

National Institutes of Health

7/1/868/31/96

Project: Research project

Troponin C
Mutation
Muscle Contraction
Skeletal Muscle
Protein Isoforms
Neuroglia
Regeneration
Wounds and Injuries
Axons
Myelin Sheath
Myosin Light Chains
Phosphorylation
Muscle Contraction
Skeletal Muscle
Binding Sites

Potential of Neuronal Nicotinic Receptors by Zinc

Luetje, C. W.

National Institutes of Health

6/1/034/30/09

Project: Research project

Nicotinic Receptors
Zinc
Acetylcholine
Binding Sites
Ligands
Neurosciences
Education
Research
Students
Mentors
Agrin
Motor Neurons
Nervous System Trauma
Neurons
Synaptic Vesicles
Phosphoric Monoester Hydrolases
Axons
Vertebrates
Growth
Cell Adhesion Molecules

REDOX STRESS COMPONENTS OF DEGENERATIVE HEART DISEASE

Webster, K. A.

National Institutes of Health

9/30/963/31/98

Project: Research project

Ontology
Neurology
Bioassay
Semantic Web
Information systems

Regulated Therapeutic Angiogenesis: for Ischemic Disease

Webster, K. A.

National Institutes of Health

4/1/034/30/16

Project: Research project

MicroRNAs
Cardiovascular Diseases
Stem Cells
Coronary Artery Disease
Vascular Endothelial Growth Factor A
Talin
Adherens Junctions
Cadherins
Cell Adhesion
Proteolysis
GTP Phosphohydrolases
Phosphoric Diester Hydrolases
GTP-Binding Proteins
Guanosine Triphosphate
GTPase-Activating Proteins
Skeletal Muscle
Sarcopenia
Muscular Dystrophies
Knockout Mice
Muscles
Laminin Receptors
Cadherins
Laminin
Growth
Neurons
Troponin
Muscle
Tropomyosin
Proteins
Antibodies
Clathrin
Endocytosis
Yeasts
Actins
Transport Vesicles
Informatics
Libraries
Molecular Probes
Proteins
Data Accuracy

The Function of Slow Skeletal TnT in Muscle Contraction

Potter, J. D.

National Institutes of Health

3/1/052/28/11

Project: Research project

Troponin T
Muscle Contraction
Skeletal Muscle
Protein Isoforms
Tropomyosin

Therapeutic angiogenesis to treat ischemic disorders

Webster, K. A.

National Institutes of Health

9/1/018/31/03

Project: Research project

Angiogenesis Inducing Agents
Dependovirus
Therapeutics
Intercellular Signaling Peptides and Proteins
Plasmids

The Role of GPR54 Signaling in Pubertal Disorders

Bianco, S.

National Institutes of Health

9/15/088/31/11

Project: Research project

Kisspeptins
Puberty
Mutation
Arrestin
Precocious Puberty

TRAINING PROGRAMS IN CARDIOVASCULAR PHARMACOLOGY

Potter, J. D., Bassett, A. & Szczesna-Cordary, D.

National Institutes of Health

7/1/763/31/13

Project: Research project

Education
Research
Modems
Research Personnel
Graduate Education
Triazines
Optic Nerve Diseases
Retinal Ganglion Cells
Regeneration
Ischemic Optic Neuropathy

TROPONIN T AND THE REGULATION OF CONTRACTION

Potter, J. D.

National Institutes of Health

9/10/988/31/03

Project: Research project

Troponin T
Myosins
Exons
Tropomyosin
Troponin